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Oxidative Stress Modulates the Expression Pattern of Peroxiredoxin-6 in Peripheral Blood Mononuclear Cells of Asthmatic Patients and Bronchial Epithelial Cells

Shim HJ, Park SY, Kwon HS, Song WJ, Kim TB, Moon KA, Choi JP, Kim SJ, Cho YS

PURPOSE: Reduction-oxidation reaction homeostasis is vital for regulating inflammatory conditions and its dysregulation may affect the pathogenesis of chronic airway inflammatory diseases such as asthma. Peroxiredoxin-6, an important intracellular anti-oxidant...
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Effect of dental bleaching on the microhardness and surface roughness of sealed composite resins

Fernandes , Strazzi-Sahyon HB, Suzuki TY, Briso AL, dos Santos PH

OBJECTIVES: The aim of this in vitro study was to evaluate the microhardness and surface roughness of composite resins before and after tooth bleaching procedures. MATERIALS AND METHODS: Sixty specimens were...
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The biofilm removal effect of MnOâ‚‚-diatom microbubbler from the dental prosthetic surfaces: In vitro study

Lee EH, Seo Y, Kwon HB, Yim YJ, Kong H, Kim MJ

PURPOSE: The aim of this study is to evaluate the effectiveness of MnOâ‚‚-diatom microbubbler (DM) on the surface of prosthetic materials as a mouthwash by comparing the biofilm removal effect...
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Quercetin-induced apoptosis ameliorates vascular smooth muscle cell senescence through AMP-activated protein kinase signaling pathway

Kim SG, Sung JY, Kim JR, Choi HC

Aging is one of the risk factors for the development of cardiovascular diseases. During the progression of cellular senescence, cells enter a state of irreversible growth arrest and display resistance...
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Protective Effects of Ursolic Acid on Osteoblastic Differentiation via Activation of IER3/Nrf2

Lee SI

BACKGROUND: Oxidative stress is a known to be associated with in the pathogenesis of many inflammatory diseases, including periodontitis. Ursolic acid is a pentacyclic triterpenoid with has antimicrobial, antioxidative, and...
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Cyclosporin A aggravates hydrogen peroxide-induced cell death in kidney proximal tubule epithelial cells

Moon D, Kim J

Cyclosporin A (CsA) does not only exert a toxic effect on kidney parenchymal cells, but also protects them against necrotic cell death by inhibiting opening of mitochondrial permeability transition pore....
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Protective effect of Cordyceps militaris against hydrogen peroxide-induced oxidative stress in vitro

He MT, Lee AY, Park CH, Cho EJ

BACKGROUND/OBJECTIVES: Excessive production of reactive oxygen species (ROS) such as hydroxyl (·OH), nitric oxide (NO), and hydrogen peroxide (H2O2) is reported to induce oxidative stress. ROS generated by oxidative stress...
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Esculetin Prevents the Induction of Matrix Metalloproteinase-1 by Hydrogen Peroxide in Skin Keratinocytes

Zhen AX, Piao MJ, Kang KA, Fernando P, Kang HK, Koh YS, Hyun JW

BACKGROUND: Reactive oxygen species (ROS) are involved in various cellular diseases. Excessive ROS can cause intracellular oxidative stress, resulting in a calcium imbalance and even aging. In this study, we...
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Beta-carotene prevents the spermatogenic disorders induced by exogenous scrotal hyperthermia through modulations of oxidative stress, apoptosis, and androgen biosynthesis in mice

Yon JM, Kim JS, Lin C, Park SG, Gwon LW, Lee JG, Baek IJ, Nahm SS, Nam SY

We investigated whether β-carotene (β-CA) or ellagic acid (EA), originating from various fruits and vegetables, has a preventive effect against male infertility induced by exogenous scrotal hyperthermia. ICR adult mice...
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A simple and effective method for addition silicone impression disinfection

Azevedo MJ, Correia I, Portela A, Sampaio-Maia B

PURPOSE: Although dental impression disinfection is determinant to reduce the cross-infection risk, some studies have shown that, in real practice, the disinfection procedures vary considerably. Thus, the aim of this...
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Antioxidant activity of ethanol extract of Lycium barbarum's leaf with removal of chlorophyll

Kim JE, Bae SM, Nam YR, Bae EY, Ly SY

PURPOSE: The aim of this study was to estimate the antioxidant activities of 50%, 70%, and 100% ethanol extracts of Lycium barbarum leaf and chlorophyll removal extract. METHODS: The antioxidant activities...
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Evaluation of the effects of whitening mouth rinses combined with conventional tooth bleaching treatments

Favaro JC, Geha O, Guiraldo R, Lopes MB, Aranha AM, Berger SB

OBJECTIVES: The aim of the present study was to evaluate the effect of whitening mouth rinses alone and in combination with conventional whitening treatments on color, microhardness, and surface roughness...
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Tooth whitening effects of manicure-type hydrogen peroxide tooth whitening gel

Kim YG, Park JH, Cho JW

OBJECTIVES: To examine the tooth whitening effects of a 3% hydrogen peroxide gel. METHODS: Twenty participants were given experimental tooth whitening gels containing 3% hydrogen peroxide, and another 20 participants, who...
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Efficacy of a self - applied paint - on whitening gel combined with wrap

Kim SY, Ahn JH, Kim JY, Kim JW, Park SH, Cho KM

PURPOSE: The aim of this clinical study was to evaluate the efficacy and safety of a self - applied paint - on whitening gel combined with wrap to increase the...
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Acer okamotoanum Inhibit the Hydrogen Peroxide-Induced Oxidative Stress in C6 Glial Cells

Choi SY, Kim JH, Quilantang NG, Lee S, Cho EJ

Chronic oxidative stress due to the accumulation of reactive oxygen species (ROS) in neuronal cells ultimately leads to neurodegenerative diseases. The use of natural therapies for the prevention of ROS-induced...
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Effect of various bleaching treatments on shear bond strength of different universal adhesives and application modes

Oz FD, Kutuk ZB

OBJECTIVES: The aim of this in vitro study was to evaluate the bond strength of 2 universal adhesives used in different application modes to bleached enamel. MATERIALS AND METHODS: Extracted 160...
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Protective effects of perilla oil and alpha linolenic acid on SH-SY5Y neuronal cell death induced by hydrogen peroxide

Lee AY, Choi JM, Lee MH, Lee J, Lee S, Cho EJ

BACKGROUND/OBJECTIVE: Oxidative stress plays a key role in neuronal cell damage, which is associated with neurodegenerative disease. The aim of present study was to investigate the neuroprotective effects of perilla...
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Hydrogen peroxide inhibits Ca²⁺ efflux through plasma membrane Ca²⁺-ATPase in mouse parotid acinar cells

Kim MJ, Choi KJ, Yoon MN, Oh SH, Kim DK, Kim SH, Park HS

Intracellular Ca²⁺ mobilization is closely linked with the initiation of salivary secretion in parotid acinar cells. Reactive oxygen species (ROS) are known to be related to a variety of oxidative...
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Cytoprotective Effect of Taurine against Hydrogen Peroxide-Induced Oxidative Stress in UMR-106 Cells through the Wnt/β-Catenin Signaling Pathway

Lou J, Han D, Yu H, Yu G, Jin M, Kim SJ

Osteoporosis development is closely associated with oxidative stress and reactive oxygen species (ROS). Taurine has potential antioxidant effects, but its role in osteoblasts is not clearly understood. The aim of...
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Melatonin Rescues Human Dental Pulp Cells from Premature Senescence Induced by Hâ‚‚Oâ‚‚

Park S, Bak KJ, Ok CY, Park HJ, Jang HO, Bae MK, Bae SK

Although anti-aging activities of melatonin, a hormone secreted by the pineal gland, have been reported in senescence-accelerated mouse models and several types of cells, its impact and mechanism on the...
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