- The Overexpression of Histone Deacetylase 1 and Its Relationship with p16INK4a Gene Hypermethylation in Pulmonary Squamous Cell Carcinoma and Adenocarcinoma
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Park JH, Hong YS, Choi PJ, Kim NY, Lee KE, Roh MS
- KMID: 2073788
- Korean J Pathol.
- 2009 Apr;43(2):107-112.
BACKGROUND: DNA methylation and histone modification are dynamically linked in the epigenetic control of gene silencing and they play an important role in tumorigenesis. METHODS: To evaluate the role of histone... -
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- A polymorphism in the histone deacetylase 1 gene is associated with the response to corticosteroids in asthmatics
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Kim MH, Kim SH, Kim YK, Hong SJ, Min KU, Cho SH, Park HW
- KMID: 1780132
- Korean J Intern Med.
- 2013 Nov;28(6):708-714.
- doi: 10.3904/kjim.2013.28.6.708
BACKGROUND/AIMS: Recent investigations suggest that histone deacetylase 1 (HDAC1) and HDAC2 may be target molecules to predict therapeutic responses to corticosteroids. We evaluated the effects of variation in HDAC1 and... -
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- HDAC1 Expression in Invasive Ductal Carcinoma of the Breast and Its Value as a Good Prognostic Factor
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Eom M, Oh SS, Lkhagvadorj S, Han A, Park KH
- KMID: 1439865
- Korean J Pathol.
- 2012 Aug;46(4):311-317.
- doi: 10.4132/KoreanJPathol.2012.46.4.311
BACKGROUND: Histone deacetylase 1 (HDAC1) is associated with the expression and function of estrogen receptors and the proliferation of tumor cells, and has been considered a very important factor in... -
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- Expressional Difference of RHEB, HDAC1, and WEE1 Proteins in the Stromal Tumors of the Breast and Their Significance in Tumorigenesis
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Eom M, Han A, Lee MJ, Park KH
- KMID: 1439867
- Korean J Pathol.
- 2012 Aug;46(4):324-330.
- doi: 10.4132/KoreanJPathol.2012.46.4.324
BACKGROUND: Fibroadenoma (FA) and phyllodes tumor (PT) are stromal tumors of breast and are histologically similar. There are no established differences in tumorigenesis and oncogene expression among them. Ras homolog... -
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- Sumoylation of histone deacetylase 1 regulates MyoD signaling during myogenesis
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Joung H, Kwon S, Kim KH, Lee YG, Shin S, Kwon DH, Lee YU, Kook T, Choe N, Kim JC, Kim YK, Eom GH, Kook H
- KMID: 2438357
- Exp Mol Med.
- 2018 Jan;50(1):e427.
- doi: 10.1038/emm.2017.236
Sumoylation, the conjugation of a small ubiquitin-like modifier (SUMO) protein to a target, has diverse cellular effects. However, the functional roles of the SUMO modification during myogenesis have not been... -
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- SUMO Proteins are not Involved in TGF-beta1-induced, Smad3/4-mediated Germline alpha Transcription, but PIASy Suppresses it in CH12F3-2A B Cells
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Lee SH, Kim PH, Oh SM, Park JH, Yoo YC, Lee J, Park SR
- KMID: 2150822
- Immune Netw.
- 2014 Dec;14(6):321-327.
- doi: 10.4110/in.2014.14.6.321
TGF-beta induces IgA class switching by B cells. We previously reported that Smad3 and Smad4, pivotal TGF-beta signal-transducing transcription factors, mediate germline (GL) alpha transcription induced by TGF-beta1, resulting in... -
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- The Modulation of Neurotrophin and Epigenetic Regulators: Implication for Astrocyte Proliferation and Neuronal Cell Apoptosis After Spinal Cord Injury
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Kim JH, Kim SH, Cho SR, Lee JY, Kim JH, Baek A, Jung HS
- KMID: 2356640
- Ann Rehabil Med.
- 2016 Aug;40(4):559-567.
- doi: 10.5535/arm.2016.40.4.559
OBJECTIVE: To investigate alterations in the expression of the main regulators of neuronal survival and death related to astrocytes and neuronal cells in the brain in a mouse model of... -
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