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Two Purification of Maltose-binding Protein(MBP) PNase H Fusion Protein with a c-myc Tag and Histidine Tail

Park SG, Chung JY, Je EY, Faik JE, Oh HK, Choi IH

  • KMID: 2099344
  • J Korean Soc Microbiol.
  • 2000 Oct;35(5):352-352.
No Abstract Available.
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Expression of Fragile Histidine Triad (FHIT) Gene Product in the Uterine Cervical Carcinoma

Lee SJ, Kim CJ

  • KMID: 1537004
  • Korean J Gynecol Oncol Colposc.
  • 1999 Sep;10(3):217-223.
To investigate the involvement of expression of the Fragile Histidine Triad(FH1T) gene product in the process of carcinogenesis and progression in cervical carcinoma, we examined its expression by immunohistochemical method...
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Biological functions of histidine-dipeptides and metabolic syndrome

Song BC, Joo NS, Aldini G, Yeum KJ

  • KMID: 2313704
  • Nutr Res Pract.
  • 2014 Feb;8(1):3-10.
The rapid increase in the prevalence of metabolic syndrome, which is associated with a state of elevated systemic oxidative stress and inflammation, is expected to cause future increases in the...
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Search for "Proximal Histidine" of Thyroperoxidase Using Site Directed Mutagenesis

Kim WB, Shong YK

  • KMID: 2200381
  • J Korean Soc Endocrinol.
  • 2003 Aug;18(4):371-378.
BACKGROUND: Thyroperoxidase (TPO), a transmembrane heme containing glycoprotein, catalyzes iodide organification and thyroid hormone synthesis. It is a single peptide making a loop with more than one disulfide bond. The...
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SLC26A4 Mutations in Korean Population

Kim BG

SLC26A4 mutations are common cause of congenital hearing loss in East Asia. The carrier frequency of SLC26A4 mutations is 1 in 75 in Korean populations. The SLC26A4 mutation spectrum varies...
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A two-component signal transduction system contributes to the virulence of Riemerella anatipestifer

Wang Q, Chen M, Zhang W

Similar to other studies of bacterial pathogens, current studies of the pathogenesis of Riemerella anatipestifer (RA) are focused mainly on in vitro culture conditions. To elucidate further the pathogenesis of...
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Abnormal Fragile Histidine Triad Gene Expression in Gastric Cancer

Lee MS, Kim TY, Cho GS, Chae MK, Kim SY, Baek MJ, Lee SH, Park KK, Kim CH, Song OP, Cho MS

  • KMID: 2372713
  • J Korean Gastric Cancer Assoc.
  • 2003 Mar;3(1):26-32.
PURPOSE: Genomic alterations and abnormal expression of the fragile histidine triad (FHIT) gene in gastric cancer were examined to determine whether the FHIT gene is actually a frequent target for...
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Proposal of Dual Inhibitor Targeting ATPase Domains of Topoisomerase II and Heat Shock Protein 90

Jun KY, Kwon Y

There is a conserved ATPase domain in topoisomerase II (topo II) and heat shock protein 90 (Hsp90) which belong to the GHKL (gyrase, Hsp90, histidine kinase, and MutL) family. The...
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Nutritional and Physicochemical Characteristics of the Antidementia Acetylcholinesterase-Inhibiting Methanol Extracts from Umbilicaria esculenta

Lee JS, Min GH, Lee JS

To develop new antidementia nutraceuticals, a potent acetylcholinesterase (AChE)-inhibiting extract was screened from various extracts of nutritional mushrooms and lichens nutritional and its physicochemical properties were investigated. Among the several...
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Clinicopathological Significance of FHIT Protein Expression in Cervical Adenocarcinoma

Lee TS, Suh DH, Kang SB

  • KMID: 2272872
  • Korean J Obstet Gynecol.
  • 2006 Aug;49(8):1690-1696.
OBJECTIVE: To investigate the expression of fragile histidine triad (FHIT) protein and the possible relationship between FHIT expression and clinicopathological indices in cervical adenocarcinoma. METHODS: FHIT protein expression was examined...
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Identification of a New Selective Chemical Inhibitor of Mutant Isocitrate Dehydrogenase-1

Kim HJ, Choi BY, Keum YS

BACKGROUND: Recent genome-wide sequencing studies have identified unexpected genetic alterations in cancer. In particular, missense mutations in isocitrate dehydrogenase-1 (IDH1) at arginine 132, mostly substituted into histidine (IDH1-R132H) were observed...
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Scombroid Fish Poisoning and Histamine Food Poisoning

Chung SP

Scombroid fish poisoning (SFP) is a form of histamine food poisoning caused by the ingestion of improperly stored fish. The term “scombroid” derives from the family name of the fish...
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Abnormal Fragile Histidine Triad (FHIT) Expression in Cervical Carcinomas

Tong SY, Lee SK, Ji SG

  • KMID: 2272360
  • Korean J Obstet Gynecol.
  • 2004 Jun;47(6):1093-1099.
OBJECTIVE: The fragile histidine triad (FHIT) gene is located at chromosome 3p14.2 and encompasses the common fragile site, FRA3B, which may contribute to chromosome breakage and rearrangement of cancer cells....
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A Case of Atypical McCune-Albright Syndrome Associated with Hyperthyroidism

Jang YS, Kang SH, Jung WR, Kim WT, Kim HS, Lee JM, Moon SD, Cha BY, Lee KW, Son HY, Kang SK

McCune-Albright syndrome (MAS) is a sporadic disease that's characterized by polyostotic fibrous dysplasia, cafe-au-lait pigmentation of the skin, and multiple endocrinopathies, including sexual precocity, hyperthyroidism, acromegaly, and hypercortisolism. Recent evidence...
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Production of Monoclonal Antibody Against Human 14 - 3 - 3 Zeta Isoform Expressed in Escherichia coli

Lim BU, Kang JS, Kim JW, Choi NJ

  • KMID: 2083005
  • Korean J Immunol.
  • 1997 Sep;19(3):391-398.
14-3-3 proteins are cytoplasmic proteins of about 29 kDa and have a minimum of seven isoforms. This protein is important in signal transduction with the ability of binding with phosphoserine...
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Suitable Conditions for Mycelial Growth of Phellinus spp.

Hur H, Imtiaj A, Lee MW, Lee TS

The fungus Phellinus is a mushroom that is widely used medicinally. The optimal conditions for mycelial growth of 13 strains of the fungus were investigated. Mycelial growth was optimal at...
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Therapeutic Effects of Amino Acids in Liver Diseases: Current Studies and Future Perspectives

Lee DY, Kim EH

Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver and the third most common cause of cancer-related death worldwide. HCC is caused by infection of hepatitis...
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Mechanism of FHIT-Induced Apoptosis in Lung Cancer Cell Lines

Yoo JS, Kim CH

BACKGROUND: The FHIT (fragile histidine triad) gene is a frequent target of deletions associated with abnormal RNA and protein expression in lung cancer. Previous studies have shown FHIT gene transfer...
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Culture Conditions Affecting the Optimal Mycelial Growth of Cystoderma amianthinum

Shim SM, Oh YH, Lee KR, Kim SH, Im KH, Kim JW, Lee UY, Shim JO, Shim MJ, Lee MW, Ro HS, Lee HS, Lee TS

Cystoderma amianthinum, one of edible fungi belongs to Agaricaceae of Basidiomycota, has a good taste and flavor. This study was carried out to obtain the basic informations for the optimum...
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The Optimal Culture Conditions Affecting the Mycelial Growth and Fruiting Body Formation of Paecilomyces fumosoroseus

Shim SM, Lee KR, Kim SH, Im KH, Kim JW, Lee UY, Shim JO, Lee MW, Lee TS

  • KMID: 2312416
  • Mycobiology.
  • 2003 Dec;31(4):214-220.
The fruiting body of Paecilomyces fumosoroseus was collected at Mt. Mani, Ganghwa Island, Korea in September, 2001. This study was carried out to obtain the basic informations for the mycelial...
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