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The effect of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion

Hwang S, Chung CJ, Choi YJ, Kim T, Kim KH

OBJECTIVE: The objective of this study was to evaluate the effects of cetirizine, a histamine 1 receptor antagonist, on bone remodeling after calvarial suture expansion. METHODS: Sixty male Sprague–Dawley rats were...
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Evaluation of symptoms and symptom combinations in histamine intolerance

Schnedl WJ, Lackner S, Enko D, Schenk M, Holasek SJ, Mangge H

BACKGROUND/AIMS: Food intolerance/malabsorption, particularly histamine intolerance (HIT), may cause nonspecific functional gastrointestinal and extraintestinal symptoms. We evaluated gastrointestinal and extraintestinal symptoms in patients with HIT. METHODS: In an analysis of outpatients'...
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Scombroid Fish Poisoning and Histamine Food Poisoning

Chung SP

Scombroid fish poisoning (SFP) is a form of histamine food poisoning caused by the ingestion of improperly stored fish. The term “scombroid” derives from the family name of the fish...
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Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal

Fabisiak A, WÅ‚odarczyk J, Fabisiak N, Storr M, Fichna J

  • KMID: 2387824
  • J Neurogastroenterol Motil.
  • 2017 Jul;23(3):341-348.
  • doi: 10.5056/jnm16203
Irritable bowel syndrome is a group of functional gastrointestinal disorders with not yet fully clarified etiology. Recent evidence suggesting that mast cells may play a central role in the pathogenesis...
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Baicalein, wogonin, and Scutellaria baicalensis ethanol extract alleviate ovalbumin-induced allergic airway inflammation and mast cell-mediated anaphylactic shock by regulation of Th1/Th2 imbalance and histamine release

Bui TT, Piao CH, Song CH, Lee CH, Shin HS, Chai OH

Asthma is characterized by chronic inflammation, goblet cell hyperplasia, the aberrant production of the Th2 cytokines, and eosinophil infiltration into the lungs. In this study, we examined the effects of...
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Effect of Different Cooking Methods on Histamine Levels in Selected Foods

Chung BY, Park SY, Byun YS, Son JH, Choi YW, Cho YS, Kim HO, Park CW

BACKGROUND: Histamine in food is known to cause food poisoning and allergic reactions. We usually ingest histamine in cooked food, but there are few studies about the influence of cooking...
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Comparison of Histamine 2 Receptor Antagonists and Proton Pump Inhibitors on Infectious Complications in Critically Ill Patients

Park SY, Choi JH, Youn YJ, Rhie SJ

BACKGROUND: The use of acid suppressive agents became a standard therapy in an intensive care unit (ICU) to prevent stress related gastrointestinal mucosal damage. However, the risk of infectious diseases...
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Correlations of nasal responses to leukotriene D4 and histamine nasal provocation with quality of life in allergic rhinitis

Zhu Z, Xie Y, Guan W, Gao Y, Xia S, Shi X, Zheng J

BACKGROUND: The symptoms of allergic rhinitis (AR) greatly affect the quality of life (QoL) in the patients with AR. The correlations of nasal response to leukotriene D4 (LTD4) and histamine...
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Blocking of Histamine Release and IgE Binding to FcepsilonRI on Human Basophils by Antibodies Produced in Camels

Khaled AQ, Sana Y, Abdulrahman R, Raida K, Sami AH

PURPOSE: The production of camel heavy-chain antihuman IgE (huIgE) that has the potential to block IgE-FcepsilonRI interaction and histamine release by basophils. METHODS: Camels were immunized with a synthetic loop peptide...
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The Modulatory Role of Spinally Located Histamine Receptors in the Regulation of the Blood Glucose Level in D-Glucose-Fed Mice

Sim YB, Park SH, Kim SS, Kim CH, Kim SJ, Lim SM, Jung JS, Ryu OH, Choi MG, Suh HW

The possible roles of spinal histamine receptors in the regulation of the blood glucose level were studied in ICR mice. Mice were intrathecally (i.t.) treated with histamine 1 (H1) receptor...
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Histamine Promotes the Release of Interleukin-6 via the H1R/p38 and NF-kappaB Pathways in Nasal Fibroblasts

Park IH, Um JY, Cho JS, Lee SH, Lee SH, Lee HM

PURPOSE: Based on the close relationship between histamine and interleukin 6 (IL-6), we hypothesized that histamine may regulate the production of cytokines, such as IL-6, during allergic inflammation. Here, we...
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Curcumin Inhibits the Activation of Immunoglobulin E-Mediated Mast Cells and Passive Systemic Anaphylaxis in Mice by Reducing Serum Eicosanoid and Histamine Levels

Li X, Lu Y, Jin Y, Son JK, Lee SH, Chang HW

  • KMID: 2048327
  • Biomol Ther.
  • 2014 Jan;22(1):27-34.
Curcumin is naturally occurring polyphenolic compound found in turmeric and has many pharmacological activities. The present study was undertaken to evaluate anti-allergic inflammatory activity of curcumin, and to investigate its...
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A Study of Histamine Content in Food in Korea

Choi JH, Park CW, Lee CH

  • KMID: 2302158
  • Korean J Dermatol.
  • 2007 Aug;45(8):768-771.
BACKGROUND: It is often stated that ingestion of food rich in histamine can result in absorption of sufficient histamine to provoke signs and symptoms of an allergic reaction. To date,...
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Prevention of ischemia-reperfusion injury in rat skin island flap: comparison of histamine receptor blocking agents with l-arginine

Seo YK, Kim UK

  • KMID: 2400581
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2006 Jul;28(4):287-294.
Vascular thrombosis and ischemic necrosis still remain the most significant threats to the survival of free flaps. To date, neutrophils have been implicated in the pathogenesis of postischemic injury. Several...
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The Effect of Histamine on Rhinovirus-16 Infection in Airway Epithelial Cells

Jang YJ, Lee SH, Kwon HJ, Lee BJ, Chung YS

  • KMID: 2276571
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Feb;49(2):182-186.
BACKGROUND AND OBJECTIVES: It is not known if allergies promote rhinovirus infections or aggravate the symptoms of common cold due to rhinoviruses. Histamine is an important immune mediator that induces...
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Changes of Serum Histamine Concentration during General Anesthesia with Propofol-N2O in Korean

Kang SS, Yang MJ, Hong SJ, Kim IS, Shin KM, Yun YJ

BACKGROUND: This study was conducted to evaluate the effect of propofol on the histamine release during general anesthesia. METHODS: Ten premedicated adult patients, ASA physical status I or II, 20-55 yrs...
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Effects of Histamine on Nerve Block with Lidocaine

Cho IH, Lee CH

BACKGROUND: The failure to achieve satisfactory anesthesia following the administration of local anesthetic agents in acute inflammatory tissues is a recognized clinical phenomenon. Many inflammatory mediators can reduce the threshold...
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Role of Endogenous Histamine on the Pathogenesis in the Endotoxin-Induced Acute Lung Injury

Kim TH, Kim EK, Yoon HJ, Kim MJ, Choi JE, Oh YM, Shim TS, Lim CM, Lee SD, Kim WS, Kim DS, Kim WD, Koh Y

BACKGROUND: Histamine is widely distributed in the lung. It increases capillary permeability and the P-selectin expression on vascular endothelial cell surfaces. We studied the role of endogenous histamine on the...
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Effect of Interleukin-9 on Cell Proliferation and Histamine Release of Cord Blood-derived Human Mast Cells

Ahn KM, Lee KS, Shin MY, Park HY, Ahn YH, Son DY, Lee SI

  • KMID: 2051388
  • Pediatr Allergy Respir Dis.
  • 2002 Dec;12(4):282-290.
PURPOSE: Interleukin-9(IL-9), one of Th2-type cytokines, might be important in the pathophysiology of allergic diseases. We investigated the effect of IL-9 on human mast cells by assessing cell proliferation and...
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Appraisal of Histamine Concentration on Skin Reactivity in Infancy

Chung YH, Lee HY

  • KMID: 2314232
  • Pediatr Allergy Respir Dis.
  • 2001 Jun;11(2):102-108.
PURPOSE: It is well known that the histamine test is essential for positive control in the evaluation of allergy skin test. Estimation of the allergen wheal size without histamine control...
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