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In Response to Risks and Pitfalls of Epidural Injections during Management of Lumbar Disc Herniation: Few Comments

Manchikanti L, Hirsch JA

No abstract available.
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RE: Efficacy of Cervical Interlaminar Epidural Steroid Injections

Manchikanti L, Benyamin R, Kaye AD, Hirsch JA

No abstract available.
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Replacing Alteplase with Tenecteplase: Is the Time Ripe?

Singh N, Menon BK, Dmytriw AA, Regenhardt RW, Hirsch JA, Ganesh A

Thrombolysis for acute ischemic stroke has predominantly been with alteplase for over a quarter of a century. In recent years, with trials showing evidence of higher rates of successful reperfusion,...
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What is the Role of Epidural Injections in the Treatment of Lumbar Discogenic Pain: A Systematic Review of Comparative Analysis with Fusion

Manchikanti L, Staats PS, Nampiaparampil DE, Hirsch JA

BACKGROUND: Lumbar discogenic pain without pain mediated by a disc herniation, facet joints, or the sacroiliac joints, is common and often results in chronic, persistent pain and disability. After conservative...
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Comparison of effectiveness for fluoroscopic cervical interlaminar epidural injections with or without steroid in cervical post-surgery syndrome

Manchikanti L, Malla Y, Cash KA, Pampati V, Hirsch JA

BACKGROUND: Neck and back pain are leading sources of disability placing substantial burden on health care systems. Surgical interventions in managing chronic neck pain secondary to various disorders continue to...
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Comparison of the Efficacy of Caudal, Interlaminar, and Transforaminal Epidural Injections in Managing Lumbar Disc Herniation: Is One Method Superior to the Other?

Manchikanti L, Singh V, Pampati V, Falco FJ, Hirsch JA

BACKGROUND: Epidural injections are performed utilizing 3 approaches in the lumbar spine: caudal, interlaminar, and transforaminal. The literature on the efficacy of epidural injections has been sporadic. There are few...
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The role of percutaneous neurolysis in lumbar disc herniation: systematic review and meta-analysis

Manchikanti L, Knezevic E, Knezevic NN, Sanapati MR, Kaye AD, Thota S, Hirsch JA

Background: Recalcitrant disc herniation may result in chronic lumbar radiculopathy or sciatica. Fluoroscopically directed epidural injections and other conservative modalities may provide inadequate improvement in some patients. In these cases,...
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Therapeutic lumbar facet joint nerve blocks in the treatment of chronic low back pain: cost utility analysis based on a randomized controlled trial

Manchikanti L, Pampati V, Kaye AD, Hirsch JA

BACKGROUND: Related to escalating health care costs and the questionable effectiveness of multiple interventions including lumbar facet joint interventions, cost effectiveness or cost utility analysis has become the cornerstone of...
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