- Protective effect of butylated hydroxylanisole against hydrogen peroxide-induced apoptosis in primary cultured mouse hepatocytes
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Hwang GH, Jeon YJ, Han HJ, Park SH, Baek KM, Chang W, Kim JS, Kim LK, Lee YM, Lee S, Bae JS, Jee JG, Lee MY
- KMID: 2160816
- J Vet Sci.
- 2015 Mar;16(1):17-23.
- doi: 10.4142/jvs.2015.16.1.17
Butylated hydroxyanisole (BHA) is a synthetic phenolic compound consisting of a mixture of two isomeric organic compounds: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole. We examined the effect of BHA against hydrogen peroxide (H2O2)-induced... -
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- Inhibition of acyl-coenzyme A:cholesterol acyltransferase stimulates cholesterol efflux from macrophages and stimulates farnesoid X receptor in hepatocytes
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An S, Jang YS, Park JS, Kwon BM, Paik YK, Jeong TS
- KMID: 1094120
- Exp Mol Med.
- 2008 Aug;40(4):407-417.
- doi: 10.3858/emm.2008.40.4.407
We investigated the mechanism of spontaneous cholesterol efflux induced by acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhibition, and how an alteration of cholesterol metabolism in macrophages impacts on that in HepG2 cells.... -
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- Protective effects of silymarin on fumonisin B1-induced hepatotoxicity in mice
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Sozmen M, Devrim AK, Tunca R, Bayezit M, Dag S, Essiz D
- KMID: 1737610
- J Vet Sci.
- 2014 Mar;15(1):51-60.
- doi: 10.4142/jvs.2014.15.1.51
The present study was conducted to investigate the effect of silymarin on experimental liver toxication induced by Fumonisin B1 (FB1) in BALB/c mice. The mice were divided into six groups... -
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- Time-course changes in the expression levels of miR-122, -155, and -21 as markers of liver cell damage, inflammation, and regeneration in acetaminophen-induced liver injury in rats
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Park HK, Jo W, Choi HJ, Jang S, Ryu JE, Lee HJ, Lee H, Kim H, Yu ES, Son WC
- KMID: 2363334
- J Vet Sci.
- 2016 Mar;17(1):45-51.
- doi: 10.4142/jvs.2016.17.1.45
Drug-induced liver injury (DILI) is a significant threat to patient health and a major concern during drug development. Recently, multiple circulating microRNAs (miRNAs) have been reported to be potential biomarkers... -
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- Inhibitory Effect of Angiotensin II Receptor Antagonist on the Contraction and Growth of Hepatic Stellate Cells
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Baik SK, Jo HS, Suk KT, Kim JM, Lee BJ, Choi YJ, Kim HS, Lee DK, Kwon SO, Lee KI, Cha SK, Park KS, Kong ID
- KMID: 772535
- Korean J Gastroenterol.
- 2003 Aug;42(2):134-141.
BACKGROUNDS/AIMS: This study aimed to investigate the effects of angiotensin II (ANG II) and its receptor antagonist (losartan) on the contraction and growth of HSCs. METHODS: HSCs were isolated... -
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