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Definition, Diagnosis, and Prevalence of Occult Hepatitis B Virus Infection

Kim YS

Occult HBV infection is characterized by the absence of serum HBsAg with persistence of low level of intrahepatic HBV DNA. Several suggested mechanisms for the origin of occult HBV infection...
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Prevention of Hepatitis B reactivation in the setting of immunosuppression

Pattullo V

Advances in the treatment of malignant and inflammatory diseases have developed over time, with increasing use of chemotherapeutic and immunosuppressive agents of a range of drug classes with varying mechanism...
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KASL Clinical Practice Guidelines: Management of chronic hepatitis B

The Korean Association for the Study of the Liver (KASL)

No abstract available.
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Occult HBV among Anti-HBc Alone: Mutation Analysis of an HBV Surface Gene and Pre-S Gene

Kim MH, Kang SY, Lee WI

PURPOSE: The aim of this study is to investigate the molecular characteristics of occult hepatitis B virus (HBV) infection in ‘anti-HBc alone’ subjects. MATERIALS AND METHODS: Twenty-four patients with ‘anti-HBc alone’...
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Risk of Pancreatic Cancer in Relation to ABO Blood Group and Hepatitis C Virus Infection in Korea: A Case-Control Study

Woo SM, Joo J, Lee WJ, Park SJ, Han SS, Kim TH, Koh YH, Kim HB, Hong EK

Several studies have reported that ABO blood group, hepatitis B virus (HBV) and hepatitis C virus (HCV) infection contribute to the development of pancreatic cancer. The aim of this study...
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Association of Polymorphism in MicroRNA 604 with Susceptibility to Persistent Hepatitis B Virus Infection and Development of Hepatocellular Carcinoma

Cheong JY, Shin HD, Cho SW, Kim YJ

MicroRNA polymorphisms may be associated with carcinogenesis or immunopathogenesis of infection. We evaluated whether the mircoRNA-604 (miR-604) polymorphism can affect the persistence of hepatitis B virus (HBV) infection, and the...
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New perspectives of biomarkers for the management of chronic hepatitis B

Lin CL, Kao JH

With recent advances in molecular and genomic investigations, the impact of hepatitis B viral and host factors on the progression of chronic HBV infection has been explored. For viral factors,...
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Management of Antiviral Resistance in Chronic Hepatitis B

Lim YS

The primary goal of therapy for chronic hepatitis B (CHB) is to prevent liver disease progression. Hepatitis B surface antigen (HBsAg) seroclearance or seroconversion is regarded as an optimal endpoint...
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Survey of perinatal hepatitis B virus transmission after Korean National Prevention Program in a tertiary hospital

Kim JH, Kim JS, Lee JJ, Kim JH, Kim SY, Jung YK, Kwon OS, Kim YS, Choi DJ, Kim JH

BACKGROUND/AIMS: The Ministry of Health and Welfare and the Korea Centers for Disease Control and Prevention in South Korea have been organizing hepatitis B virus (HBV) vertical infection prevention projects...
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Overlapping Gene Mutations of Hepatitis B Virus in a Chronic Hepatitis B Patient with Hepatitis B Surface Antigen Loss during Lamivudine Therapy

Lee SY, Choi MS, Lee D, Lee JH, Koh KC, Paik SW, Yoo BC

Disappearance of hepatitis B surface antigens (HBsAg) in chronic hepatitis B usually indicates clearance of hepatitis B virus (HBV) infection. However, false HBsAg negativity with mutations in pre-S2 and 'a'...
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Recent trends in hepatitis B virus infection in the general Korean population

Kim H, Shin AR, Chung HH, Kim MK, Lee JS, Shim JJ, Kim BH

BACKGROUND/AIMS: Hepatitis B virus (HBV) is the major cause of chronic liver disease in Korea, but viral prevalence has decreased because of hepatitis B vaccination programs. In this study, we...
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A study of hepatitis B virus reactivation associated with rituximab therapy in real-world clinical practice: a single-center experience

Oh MJ, Lee HJ

BACKGROUND/AIMS: The widespread use of cytotoxic chemotherapy and immunosuppressants has resulted in reactivation of hepatitis B virus (HBV) recently becoming an issue. Although rituximab (an anti-CD20 monoclonal antibody) has revolutionized...
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Status of Primary Liver Cancer Found through Routine Health Check-up

Lee C, Yang JI, Byun HJ, Kang JM, Choi S, Yim JY

This study aimed to investigate the status of primary liver cancers found through a routine health check-up. The data of subjects who were diagnosed with primary liver cancer for the...
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Familial clustering of hepatitis B and C viruses in Korea

Kim YS, Ahn YO, Kim DW

In order to evaluate the familial clustering of hepatitis B virus(HBV) and hepatitis C virus(HCV) infections and to elucidate the possible routes of HCV transmission among Korean adults with chronic...
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Shifting Prevalence of Gallbladder Polyps in Korea

Lee YJ, Park KS, Cho KB, Kim ES, Jang BK, Chung WJ, Hwang JS

Only a few studies have evaluated the population-adjusted prevalence of gallbladder polyps (GBP). This study aimed to evaluate the changes in GBP prevalence and risk factors at a single health...
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Factors influencing the severity of acute viral hepatitis A

Kim JI, Kim YS, Jung YK, Kwon OS, Kim YS, Ku YS, Choi DJ, Kim JH

BACKGROUND/AIMS: Most patients with acute viral hepatitis A have a favorable course, but a few of them suffer from severe forms of hepatitis such as fulminant hepatitis. This study was...
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Relationship of Oxidative Stress in Hepatitis B Infection Activity with HBV DNA and Fibrosis

Duygu F, Karsen H, Aksoy N, Taskin A

BACKGROUND: The aim of this study was to evaluate oxidative stress in various clinical forms of hepatitis B infection and to investigate its role in the development of the chronic...
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Prevalence of viral hepatitis markers in Korean patients with hepatocellular carcinoma

Huh K, Choi SY, Whang YS, Lee DS

The positive rates of hepatitis B surface antigen (HBsAg) and antibody to hepatitis C virus (anti-HCV) were analyzed according to year, sex, age, and serum ALT levels in 1,370...
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Seroprevalence of Hepatitis B Virus among Health Care Workers in Korea

Shin BM, Yoo HM, Lee AS, Park SK

We studied the seroprevalence of HBsAg, anti-HBs and anti-HBc and the vaccination histories among health care workers (HCWs) at a large suburban referral hospital in Korea. The purpose of this...
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Clinical significance of occult hepatitis B virus infection in chronic hepatitis C patients

Jang JY, Jeong SW, Cheon SR, Lee SH, Kim SG, Cheon YK, Kim YS, Cho YD, Kim HS, Jin SY, Kim YS, Kim BS

BACKGROUND/AIMS: We investigated the frequency of occult hepatitis B virus (HBV) infection in anti-hepatitis C virus (HCV)-positive individuals and the effects of occult HBV infection on the severity of liver...
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