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Nitric oxide in liver fibrosis: The role of inducible nitric oxide synthase

Iwakiri Y

The inducible form of nitric oxide synthase (iNOS) is expressed in hepatic cells in pathological conditions. Its induction is involved in the development of liver fibrosis, and thus iNOS could...
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NADPH oxidase mediated oxidative stress in hepatic fibrogenesis

Paik YH, Brenner DA

NADPH oxidase (NOX) is a multicomponent enzyme complex that generates reactive oxygen species (ROS) in response to a wide range of stimuli. ROS is involved as key secondary messengers in...
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Pathophysiology of Portal Hypertension, What's New?

Kim MY, Baik SK

Portal hypertension (PHT) is associated with changes in the intrahepatic, systemic and portosystemic collateral circulations. Alteration in vasoreactivity (vasodilation and vasoconstriction) plays a central role in the pathogenesis of PHT...
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Hemodynamic alterations in cirrhosis and portal hypertension

Kim MY, Baik SK, Lee SS

Portal hypertension (PHT) is associated with hemodynamic changes in intrahepatic, systemic, and portosystemic collateral circulation. Increased intrahepatic resistance and hyperdynamic circulatory alterations with expansion of collateral circulation play a central...
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