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Relationship between Helicobacter pylori Virulence Genes and Clinical Outcomes in Saudi Patients

Marie MA

Helicobacter pylori has been strongly associated with gastritis, gastric and duodenal ulcers, and it is a risk factor for gastric cancer. Two major virulence factors of H. pylori have been...
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Development of epidemiological method for the Helicobacter pylori by polymerase chain reaction

Lee WK, Cho MJ, Choi HJ, Rhee KH

The polymerase chain reaction was used to develop a method for the detection of Helicobacter pylori, a causative agent of gastritis, as well as for the elucidation of its mode...
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Examination of Geographical, Clinical and Intrahost Variations in the 3' Repeat Region of CagA Gene in Helicobacter pylori

Park SY, Lee YD, Kim SK

The size variation of the cytoxin-associated protein (cagA), which is dependent on the 3' repeat region (3'RR) of the cagA gene, is known to play a crucial role in the...
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Diverse VacA Allelic Types of Helicobacter pylori in Korea and Clinical Correlation

Choe YH, Kim PS, Lee DH, Kim HK, Kim YS, Shin YW, Hwang TS, Kim HJ, Song SU, Choi MS

Helicobacter pylori has a diversity of vacA allelic types. The purpose of this study was to correlate the vacA status and the clinical outcome. After constructing specific primers for the...
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Expression of MicroRNA in Host Cells Infected with Helicobacter pylori

Chung JW, Jeong SH, Lee SM, Pak JH, Lee GH, Jeong JY, Kim JH

BACKGROUND/AIMS: MicroRNAs (miRNAs) regulate gene expression. We assess miRNA regulation by Helicobacter pylori infection and elucidate their role in H. pylori-infected gastric epithelial cells. METHODS: The relationship between miRNA expression and...
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High Prevalence of Multiple Strain Colonization of Helicobacter pylori in Korean Patients: DNA Diversity Among Clinical Isolates from the Gastric Corpus, Antrum and Duodenum

Kim JW, Kim JG, Chae SL, Cha YJ, Park SM

  • KMID: 759677
  • Korean J Intern Med.
  • 2004 Mar;19(1):1-9.
BACKGROUND: The aims of our study were to determine the correlation of the strain variation and degree of homogeneity of infecting Helicobacter pylori (H. pylori) with their disease outcomes, and...
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An Inverse Relationship between the Expression of the Gastric Tumor Suppressor RUNX3 and Infection with Helicobacter pylori in Gastric Epithelial Dysplasia

Chung WC, Jung SH, Joo KR, Kim MJ, Youn GJ, Kim Y, Lee JS, Lee H, Jung JH, Lee YK

  • KMID: 1712329
  • Gut Liver.
  • 2013 Nov;7(6):688-695.
BACKGROUND/AIMS: This study was performed to determine the association between RUNX3 expression and Helicobacter pylori infection in premalignant gastric lesions. METHODS: We examined 107 patients with gastric epithelial dysplasia who had...
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