- Hsp70 Knockdown by siRNA Decreased Collagen Production in Keloid Fibroblasts
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Shin JU, Lee WJ, Tran TN, Jung I, Lee JH
- KMID: 2345891
- Yonsei Med J.
- 2015 Nov;56(6):1619-1626.
- doi: 10.3349/ymj.2015.56.6.1619
PURPOSE: There are currently no consistently effective treatments for the excessive collagen produced by keloid fibroblasts. Previously, we reported that heat shock protein 70 (Hsp70) is up-regulated in keloid fibroblasts... -
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- Heat shock protein 70 alters the endosome-lysosomal localization of huntingtin
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Kang BS, Ahn JY, Kim MK, Kim HJ, Kang L, Lim HC, Park KS, Lee JS, Seo JS, Cha CI, Kim SU, Park YJ, Kim M
- KMID: 1103679
- Exp Mol Med.
- 2007 Feb;39(1):38-46.
Huntington's disease is caused by CAG trinucleotide expansions in the gene encoding huntingtin. N- terminal fragments of huntingtin with polyglutamine produce aggregates in the endosome-lysosomal system, where proteolytic fragments of... -
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- The effects of nonyl phenoxypolyethoxyl ethanol on cell damage pathway gene expression in SK-NSH cells
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Park S, Hwang IW, Kim JS, Kang HC, Park SY, Gil HW, Song HY, Hong SY
- KMID: 2381592
- Korean J Intern Med.
- 2015 Nov;30(6):873-883.
- doi: 10.3904/kjim.2015.30.6.873
BACKGROUND/AIMS: Most pesticide formulations contain both chief and additive ingredients. But, the additives may not have been tested as thoroughly as the chief ingredients. The surfactant, nonyl phenoxypolyethoxylethanol (NP40), is... -
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- Isoflavone-deprived soy peptide suppresses mammary tumorigenesis by inducing apoptosis
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Park K, Choi K, Kim H, Kim K, Lee MH, Lee JH, Kim Rim JC
- KMID: 756229
- Exp Mol Med.
- 2009 Jun;41(6):371-380.
- doi: 10.3858/emm.2009.41.6.042
During carcinogenesis, NF-kappaB mediates processes associated with deregulation of the normal control of proliferation, angiogenesis, and metastasis. Thus, suppression of NF-kappaB has been linked with chemoprevention of cancer. Accumulating findings... -
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- Pseudomonas aeruginosa Exotoxin A Reduces Chemoresistance of Oral Squamous Carcinoma Cell via Inhibition of Heat Shock Proteins 70 (HSP70)
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Park SR, Lee KD, Kim UK, Gil YG, Oh KS, Park BS, Kim GC
- KMID: 1071422
- Yonsei Med J.
- 2010 Sep;51(5):708-716.
- doi: 10.3349/ymj.2010.51.5.708
PURPOSE: Oral squamous carcinoma (OSCC) cells exhibit resistance to chemotherapeutic agent-mediated apoptosis in the late stage of malignancy. Increased levels of heat shock proteins 70 (HSP70) in cancer cells are... -
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- Pulmonary Disease Caused by Mycobacterium xenopi: The First Case in Korea
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Park HY, Koh WJ, Kwon OJ, Lee NY, Shim YM, Park YK, Bai GH, Mun HS, Kim BJ
- KMID: 1122628
- Yonsei Med J.
- 2007 Oct;48(5):871-875.
- doi: 10.3349/ymj.2007.48.5.871
Mycobacterium xenopi is a nontuberculous mycobacterium (NTM) that rarely causes pulmonary disease in Asia. Here we describe the first case of M. xenopi pulmonary disease in Korea. A 66-year-old man... -
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