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DNA sequences of the HLA-DRB1 chain from HLA-DR4 subtype alleles

Rhyu MG, Lim BU, Kim GR

  • KMID: 1690594
  • Korean J Immunol.
  • 1993 May;15(1):119-127.
No abstract available.
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HLA-DQA1, HLA-DQB1 & HLA-DRB1 Alleles Distribution in Hepatitis B Vaccine Non-responder

Kim IT, Cho YJ, Kim YT

  • KMID: 1573005
  • Korean J Immunol.
  • 2000 Jun;22(2):81-86.
No abstract available.
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Distributions of Alleles and Haplotypes of HLA - DRB1, - DQA1 and - DQB1 in Koreans

Han H, Kim TG, Choi HB, Chung TJ, Chung SY, Kim CK

  • KMID: 2083014
  • Korean J Immunol.
  • 1998 Mar;20(1):47-54.
The thirteen DRB1, 6 DQA1, and 5 DQB1 alleles were defined in 362 healthy Korean controls using reverse dot blot hybridization method. The twenty-four immobilized SSOs for DRB1, 8 for...
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Usefulness of PCR-SSP Method for Detection of HLA-DRB1*0405

Kim YH, Lee KH, Kwon OJ, Seok JH, Cho YS

  • KMID: 2116912
  • J Lab Med Qual Assur.
  • 2007 Jun;29(1):201-205.
BACKGROUND: The association between HLA-DRB1 gene and severity of rheumatoid arthritis (RA) has been documented in various reports. Especially, DRB1*0405 allele shows significant association with RA in Korean patients. DRB1*0405...
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HLA-DQA1, HLA-DQB1, and HLA-DRB1 Allele Frequency in Korean Patients with Schizophrenia

Shin KS, Lee MS, Kim YR, Kim YT, Cho YJ

  • KMID: 2340476
  • J Korean Neuropsychiatr Assoc.
  • 2000 Jul;39(4):746-753.
OBJECTIVE: The aim of this study was to investigate the correlation between HLA-DQA1, HLA-DQB1 and HLA-DRB1 alleles and disease susceptibility in Korean schizophrenic patients. METHODS: HLA-DQA1, HLA-DQB1, and HLA-DRB1 allele typing...
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Human Leukocyte Antigen-DRB1 Associations in Korean Juvenile Rheumatoid Arthritis

Lee CJ, Sohn TY, Lee DH, Lee HR, Kim M, Kim KN

OBJECTIVE: The aim of this study is to investigate the association of different subgroups of juvenile rheumatoid arthritis (JRA) with human leukocyte antigen (HLA) class II DR alleles. METHODS: One hundred...
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HLA-DQA1, HLA-DQB1, HLA-DRB1 in Korean Patients with Pulmonary Tuberculosis-by the polymerase chain reaction-sequence specific oligonucleotide probes (PCR-SSOP) method

Kim YR, Kim HJ, Cho YJ

  • KMID: 1550834
  • Korean J Infect Dis.
  • 1999 Oct;31(5):402-409.
BACKGROUND: Pulmonary tuberculosis is affected by environmental factors, such as hygiene, nutrition, and socioeconomic status. Recently it has also been shown to be correlated with specific HLA types in foreign...
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Association of HLA-DRB1 genotype with sensitivity to house dust mite

Son JW, Chung JW, Lee BJ, Kim YK, Cho SH, Min KU, Koh YY, Kim YY

  • KMID: 2286053
  • J Asthma Allergy Clin Immunol.
  • 1999 Jun;19(3):442-451.
BACKGROUND: It is known that HLA molecule can restrict specific IgE responses, but few studies have documented the association between HLA and sensitization to house dust mite(HDM). OBJECTIVE: To evaluate...
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HLA-DQB1 allele frequencies and haplotypic associations with DRB1 genes in Koreans

Lim YA, Kwak YS

  • KMID: 2031021
  • Korean J Clin Pathol.
  • 1999 Oct;19(5):535-541.
BACKGROUND: The HLA-DR and DQ genes are known to show in strong linkage disequilibrium. Authors investigated the allele frequencies of HLA-DQB1 genes and HLA-DQB1-DRB1 haplotypic associations in Koreans. METHODS: HLA-DRB1...
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Prevalence, Risk Factors, and Expression of Human Leukocyte Antigen-DRB1 in Juvenile Idiopathic Arthritis-associated Uveitis

Pyo JK, Lee S, Kim KN

OBJECTIVE: This study investigated the prevalence and risk factors of juvenile idiopathic arthritis (JIA)-associated uveitis (JIA-U) in a pediatric tertiary center in Korea. In addition, this study examined whether a...
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Association between Korean Schizophrenics and HLA-DRB1 Alleles

Hwang NY, Kim JW, Oh HB, Cho JH, Oh SY, Hong JP, Park JI, Lee DE

  • KMID: 2340488
  • J Korean Neuropsychiatr Assoc.
  • 2000 Sep;39(5):889-897.
OBJECTIVE: A genetic predisposition is widely accepted in schizophrenia. This study was intended to find any association of HLA-DRB1 alleles with Korean schizophrenics and thereby compare the results of other...
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Diversity of HLA-A26 Alleles and Haplotypes in Koreans

Whang DH, Park MH

  • KMID: 1866521
  • Korean J Lab Med.
  • 2003 Feb;23(1):52-56.
BACKGROUND: HLA-A26 is an antigen belonging to the HLA-A10 crossreacting group and shows a gene frequency of 6.7% in Koreans. A26 is encoded by at least 17 distinct alleles. In...
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Diversity of HLA-B*40 Alleles and Haplotypes in Koreans

Whang DH, Park MH

  • KMID: 1866520
  • Korean J Lab Med.
  • 2003 Feb;23(1):45-51.
BACKGROUND: HLA-B40 includes two serologic specificities, B60 and B61, and at least 45 alleles of the B*40 group have been identified. B40 shows a gene frequency of 13.4% (B60 4.5%,...
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Association of HLA - DR Genes with Systemic Sclerosis in Koreans

Kang SH, Park MH, Song YW, Cha HS, Han CW, Lee EB, Baek HJ

  • KMID: 2202538
  • J Korean Rheum Assoc.
  • 1998 Mar;5(1):11-24.
OBJECTIVE: This study was conducted to elucidate the associations of HLA with systemic sclerosis (SSc) in Koreans. METHODS: HLA associations with SSc according to SSc-specific autoantibody status and clinical subsets...
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The Clinical Significance of Shared Epitope in Rheumatoid Arthritis

Minn DS, Kim TY

  • KMID: 1587014
  • J Korean Rheum Assoc.
  • 2001 Mar;8(1):34-40.
OBJECTIVE: The application of DNA sequencing and molecular-based typing to detect HLA-DRB1 alleles showed that those associated with rheumatoid arthritis (RA)shared a consensus amino acid sequence (QKRAA or QRRAA)at positions...
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The HLA-DRB1 Polymorphism is Associated With Atopic Dermatitis, but not Egg Allergy in Korean Children

Park H, Ahn K, Park MH, Lee SI

PURPOSE: We investigated whether particular HLA-DRB1 polymorphisms contribute to egg allergy development in Korean children with atopic dermatitis (AD). METHODS: HLA-DRB1 alleles were determined by PCR-sequence-specific oligonucleotide (SSO) and PCR-single-strand conformation...
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A case of insulin autoimmune syndrome related to alpha-lipoic acid

Chang HJ, Choi HS, Park MY, Leem SM, Jang YS, Park KS, Lee JM

  • KMID: 2257626
  • Korean J Med.
  • 2009 May;76(5):600-604.
Insulin autoimmune syndrome is characterized by spontaneous hypoglycemia, high concentrations of serum immunoreactive insulin, and the presence of autoantibodies to insulin without previous insulin injection. A 71-year-old woman with diabetes,...
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Frequencies of HLA-DRB1 Alleles in Korean Patients with Pemphigus

Yang HY, Lee CW, Kim SC, Chung JH, Yu HJ, Hwang JJ

  • KMID: 2230569
  • Korean J Dermatol.
  • 1998 Apr;36(2):252-260.
BACKGROUND AND OBJECTIVES: Pemphigus is an autoimmune bullous disease of the skin and mucous membranes. There are two major types of pemphigus, namely pemphigus vulgaris(PV) and pemphigus foliaceus(PF) which can...
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Evaluation of the NeoDin SSP(TM) HLA-DR Typing Kit

Song EY, Park HJ, Park MH

  • KMID: 1730145
  • Korean J Lab Med.
  • 2003 Oct;23(5):345-351.
BACKGROUND: For HLA-DR typing, PCR-SSO (sequence specific oligonucleotide) kits are most commonly used in Korea. However, the PCR-SSO method generally shows more ambiguities than PCR-SSP (sequence specific primer) method in...
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Genetic susceptibility factors of rheumatoid arthritis

Lee HS

  • KMID: 2256060
  • Korean J Med.
  • 2008 Nov;75(5):515-524.
Rheumatoid arthritis (RA) is a chronic autoimmune disease that mainly involves the joints. Although the full etiology remains unclear, both genetic and environmental factors contribute to disease. Recently, genetic studies...
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