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A Fatal Case in Pregnant Woman Infected by H1N1 2009 in Korea

Hur JA

Pregnant women is known to be at risk of high morbiding and mortality from H1N1 2009. Since the emergence of H1N1 2009 in Korean in April 2009, fatal case has...
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Work-Relatedness of Occupational Contact Dermatitis in a Tire Factory

Choi S, Song HS, Lee CG

  • KMID: 2035721
  • Korean J Occup Environ Med.
  • 2009 Dec;21(4):354-364.
OBJECTIVES: This study investigated occupational contact dermatitis in a tire factory, prompted by a long history of complaints of skin ailments by the factory workers. METHODS: Participants (n=160) completed a questionnaire...
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A Case of Acute Pulmonary Thromboembolism Complicated Pandemic Influenza (H1N1 2009)

Lee JH, Kim M, Lee J, Kim J, Shin SY

  • KMID: 2406177
  • Infect Chemother.
  • 2010 Apr;42(2):127-131.
During the pandemic, few patients have suffered from severe pneumonia leading to acute respiratory distress syndrome (ARDS) and multiple organ dysfunction necessitating prolonged intensive care with higher mortality. Although sepsis...
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Protease Inhibitor Treatment of Disseminated Intravascular Coagulation Associated with Aortic Dissection

Ko SM, Kim N, Kim C, Cho JH, Lee EY, Huh K, Kim DK

  • KMID: 2264250
  • Korean J Med.
  • 2012 Mar;82(3):341-346.
Disseminated intravascular coagulation (DIC) is a rare complication of aortic dissection. We report an unusual case of a 64-year-old woman with DIC associated with chronic aortic dissection who developed catastrophic...
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Nafamostat for Prophylaxis against Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis Compared with Gabexate

Chang JH, Lee IS, Kim HK, Cho YK, Park JM, Kim SW, Choi MG, Chung IS

  • KMID: 2284064
  • Gut Liver.
  • 2009 Sep;3(3):205-210.
BACKGROUND/AIMS: The protease inhibitors, nafamostat and gabexate, have been used to prevent pancreatitis related to endoscopic retrograde cholangiopancreatography (ERCP). In vitro, nafamostat inhibits the pancreatic protease activities 10-100 times more...
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A Study on Anlaysis of Patch Test Positive Reactivity according to the Reading Time with T.R.U.E. TEST(R)

Lee HE, Lee JS, Lee SY

  • KMID: 2088652
  • Korean J Dermatol.
  • 2013 Feb;51(2):87-93.
BACKGROUND: The patch test is widely used for diagnosis of allergic contact dermatitis. However, nearly half of positive reactions can be observed only on day 2 or day 4 and...
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Aging impairs vasodilatory responses in rats

Kim SY, Park JT, Park JK, Lee JS, Choi JC

BACKGROUND: Aging causes profound changes of stiffness and compliance in the cardiovascular system, which contributes to decreased cardiovascular reserve. Mechanisms of the underlying endothelial vasodilator dysfunction in vasodilator signaling pathways...
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A case involving the use of nafamostat mesilate as an anticoagulant during extracorporeal membrane oxygenation in acute myocardial infarction

Hong WK, Kim GW, Lee SH, Lee WJ, Yoon DH, Kim HS, Han SJ

  • KMID: 2259121
  • Korean J Med.
  • 2010 Aug;79(2):181-186.
It is essential during extracorporeal membrane oxygenation (ECMO) to extend the activated clotting time (ACT) using anticoagulants to prevent blood clot formation. Traditionally, heparin has been used as an anticoagulant...
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Actions of potassium channel openers in rat detrusor urinae

Kim SJ, Kim NS, Lee JL

This study was performed to investigate the action of potassium channel openers on the mechanical activity of detrusor muscle isolated from rats. Detrusor muscle strips, 15 mm in length, were...
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Patch Test (T.R.U.E. Test) Results in Patients with Allergic Contact Dermatitis: 2007~2011, Chungcheongnamdo

Oh SJ, Lee JS, Lee SY

  • KMID: 2246585
  • Korean J Dermatol.
  • 2013 Sep;51(9):665-672.
BACKGROUND: A number of skin manifestations in patients with allergic contact dermatitis result from sensitization with specific allergens, and patch testing is used as a diagnostic means of identifying theses...
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Risk Factors for Post-ERCP Pancreatitis in Patients Pretreated with Nafamostat Mesilate

Kim ID, Kang DH, Park JH, Bae JH, Kim PJ, Kim YW, Choi CW, Eum JS, Lee SM, Kim TO, Kim GH, Song GA

  • KMID: 2084531
  • Korean J Gastrointest Endosc.
  • 2008 Oct;37(4):265-270.
BACKGOUND/AIMS: Pancreatitis is the most common and important complication of an endoscopic retrograde cholangiopancreatography (ERCP). The aim of this study was to identify risk factors for post ERCP-pancreatitis in patients...
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A novel Na+-dependent transporter and NHE3 mediate H+ efflux in the luminal membrane of the pancreatic duct: regulation by cAMP

Lee MG, Ahn W, Choi JY, Muallem S, Kim KH

No abstract available.
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Kainic Acid-induced Neuronal Death is Attenuated by Aminoguanidine but Aggravated by L-NAME in Mouse Hippocampus

Byun JS, Lee SH, Jeon SH, Kwon YS, Lee HJ, Kim SS, Kim YM, Kim MJ, Chun W

Nitric oxide (NO) has both neuroprotective and neurotoxic effects depending on its concentration and the experimental model. We tested the effects of NG-nitro-L-arginine methyl ester (L-NAME), a nonselective nitric oxide...
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Low-Dose Nafamostat Mesilate in Hemodialysis Patients at High Bleeding Risk

Kim EY, Lee YK, Lee SM, Choi MJ, Song YR, Kim SJ, Park TJ, Kim SG, Oh J, Seo JW, Yoon JW, Koo JR, Kim HJ, Noh JW

  • KMID: 2307157
  • Korean J Nephrol.
  • 2011 Jan;30(1):61-66.
PURPOSE: Systemic anticoagulation, usually with heparin, is required to prevent thrombosis in the blood circuit of hemodialysis. In patients at high bleeding risk, strategies to minimize the bleeding risk include...
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Inducible nitric oxide synthase is involved in neuronal death induced by trimethyltin in the rat hippocampus

Jang S, Choi S, Park C, Ahn M, Shin T, Kim S

  • KMID: 1991798
  • Korean J Vet Res.
  • 2011 Sep;51(3):185-191.
Trimethyltin chloride (TMT) has been used as a neurotoxin for inducing brain dysfunction and neuronal death. Neuronal death in the hippocampus by TMT may generate excessive nitric oxide, but there...
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Saline Versus Nafamostat Mesilate Anticoagulation for Continuous Veno-venous Hemofiltration (CVVH) in Patients at High Risk of Bleeding: A Prospective Study

Park II, Choi MJ, Yoon JW, Lee YK, Kim SG, Oh JE, Seo JW, Kim HJ, Noh JW, Koo JR

  • KMID: 1465940
  • Korean J Nephrol.
  • 2009 May;28(3):205-210.
PURPOSE:In patients with a higherrisk of bleeding, performing CVVH with heparin or saline anticoagulation is associated with increased bleeding or thrombotic risk. Nafamostat mesilate (NM), a serine proteinase inhibitor, while...
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Nafamostat Mesilate: Can It Be Used as a Conduit Preserving Agent in Coronary Artery Bypass Surgery?

Yoon YS, Oh H, Kim Y, Lim SP, Kim CS, Kang MW

  • KMID: 1987360
  • Korean J Thorac Cardiovasc Surg.
  • 2013 Dec;46(6):413-425.
BACKGROUND: Graft vessel preservation solution in coronary artery bypass surgery is used to maintain the graft conduit in optimal condition during the perioperative period. Nafamostat mesilate (NM) has anticoagulation and...
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Apoptosis Gene Expression Pattern Analysis of Jurkat Cells Treated with FK506

Jang TY, Lee JS, Woo GW, Kim HC, Lee HK, Chung SY

PURPOSE: FK506 (tacrolimus) is a widely used immunosuppressive agent in the treatment of various medical conditions, including autoimmune disease, bone marrow and organ transplantations. Previously FK506 was known to cause...
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Relaxing Effect of Acetylcholine on Phenylephrine-Induced Contraction of Isolated Rabbit Prostate Strips Is Mediated by Neuronal Nitric Oxide Synthase

Nguyen HB, Lee SY, Park SH, Lee MY, Chang IH, Myung SC

PURPOSE: The location of acetylcholinesterase-containing nerve fibers suggests a role for acetylcholine in both contractility and secretion in the prostate gland. The colocalization of nitrergic nerves with cholinergic nerves, and...
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Comparison of Efficacy of Intravenous Peramivir and Oral Oseltamivir for the Treatment of Influenza: Systematic Review and Meta-Analysis

Lee J, Park JH, Jwa H, Kim YH

PURPOSE: Peramivir is the first intravenously administered neuramidase inhibitor for immediate delivery of an effective single-dose treatment in patients with influenza. However, limited data are available on intravenous (IV) peramivir...
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