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Hypotensive Effect of Guanabenz Acetate(Rexitene(R))in Essential Hypertension;A Clinical Study

Jeong JW, Park YK, Park OK, Park JC, Jeong MH, Cho JG, Kang JC

To evaluate the hypertensive effect of guanbenz acetate, we performed a prospective clinical study for 10 weeks or more in 27 patients with essential hypertension(mean age: 51, mean supine blood...
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Guanabenz Acetate Induces Endoplasmic Reticulum Stress–Related Cell Death in Hepatocellular Carcinoma Cells

Kang HJ, Seol HS, Lee SE, Suh YA, Kim J, Jang SJ, Yu E

BACKGROUND: Development of chemotherapeutics for the treatment of advanced hepatocellular carcinoma (HCC) has been lagging. Screening of candidate therapeutic agents by using patient-derived preclinical models may facilitate drug discovery for...
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