- Neoadjuvant Chemotherapy–Guided Bladder-Sparing Treatment for Muscle-Invasive Bladder Cancer: Results of a Pilot Phase II Study
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Shi H, Zhang W, Bi X, Wang D, Xiao Z, Guan Y, Guan K, Tian J, Bai H, Hu L, Cao C, Jiang W, Hu Z, Zhang J, Chen Y, Zheng S, Feng X, Li C, Li Y, Ma J, Liu Y, Zhou A, Shou J
- KMID: 2521590
- Cancer Res Treat.
- 2021 Oct;53(4):1156-1165.
- doi: 10.4143/crt.2020.1356
Purpose Reduced quality of life after cystectomy has made bladder preservation a popular research topic for muscle-invasive bladder cancer (MIBC). Previous research has indicated significant tumor downstaging after neoadjuvant chemotherapy... -
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- Tunicamycin enhances TRAIL-induced apoptosis by inhibition of cyclin D1 and the subsequent downregulation of survivin
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Zhang HY, Du ZX, Liu BQ, Gao YY, Meng X, Guan Y, Deng WW, Wang HQ
- KMID: 1123811
- Exp Mol Med.
- 2009 May;41(5):362-369.
- doi: 10.3858/emm.2009.41.5.041
TNF-related apoptosis-inducing ligand (TRAIL) has been proposed as a promising cancer therapy that preferentially induces apoptosis in cancer cells, but not most normal tissues. However, many cancers are resistant to... -
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- Combination of Magnetic Resonance Spectroscopy and ¹¹C-Methionine Positron Emission Tomography for the Accurate Diagnosis of Non-Enhancing Supratentorial Glioma
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Kudulaiti , Qiu T, Lu J, Zhang H, Zhang Z, Guan Y, Zhuang D, Wu J
- KMID: 2447075
- Korean J Radiol.
- 2019 Jun;20(6):967-975.
- doi: 10.3348/kjr.2018.0690
OBJECTIVE: To evaluate whether the combination of magnetic resonance spectroscopy (MRS) and 11C-methionine positron emission tomography (11C-MET PET) could increase accurate diagnostic sensitivity for non-enhancing supratentorial gliomas. MATERIALS AND METHODS: Between... -
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- Glucosamine induces cell death via proteasome inhibition in human ALVA41 prostate cancer cell
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Liu BQ, Meng X, Li C, Gao YY, Li N, Niu XF, Guan Y, Wang HQ
- KMID: 1022124
- Exp Mol Med.
- 2011 Sep;43(9):487-493.
- doi: 10.3858/emm.2011.43.9.055
Glucosamine, a naturally occurring amino monosaccharide, has been reported to play a role in the regulation of apoptosis more than half century. However the effect of glucosamine on tumor cells... -
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- Olanzapine May Inhibit Colonic Motility Associated with the 5-HT Receptor and Myosin Light Chain Kinase
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Zhang J, Qiao Y, Le J, Sun D, Guan Y, Li Z
- KMID: 2316621
- Psychiatry Investig.
- 2016 Mar;13(2):232-238.
- doi: 10.4306/pi.2016.13.2.232
OBJECTIVE: To study whether the effects of olanzapine on gastrointestinal motility is related to the serotonin antagonism and myosin light chain kinase. METHODS: Male Sprague-Dawley rats were randomly divided into four... -
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- Induced Intermediate Mesoderm Combined with Decellularized Kidney Scaffolds for Functional Engineering Kidney
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Zhang J, Li K, Kong F, Sun C, Zhang D, Yu X, Wang X, Li X, Liu T, Shao G, Guan Y, Zhao S
- KMID: 2464070
- Tissue Eng Regen Med.
- 2019 Oct;16(5):501-512.
- doi: 10.1007/s13770-019-00197-9
BACKGROUND: Chronic kidney disease is a severe threat to human health with no ideal treatment strategy. Mature mammalian kidneys have a fixed number of nephrons, and regeneration is difficult once... -
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