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Accuracy and Performance Evaluation of Triplet Repeat Primed PCR as an Alternative to Conventional Diagnostic Methods for Fragile X Syndrome

Gu H, Kim MJ, Yang D, Song JY, Cho SI, Park SS, Seong MW

Background: Conventional diagnosis of fragile X syndrome (FXS) is based on a combination of fragment analysis (FA) and Southern blotting (SB); however, this diagnostic approach is time- and labor-intensive and...
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Hesperetin suppresses LPS/high glucose-induced inflammatory responses via TLR/MyD88/NF-κB signaling pathways in THP-1 cells

Lee A, Gu H, Gwon MH, Yun JM

BACKGROUND/OBJECTIVES: Unregulated inflammatory responses caused by hyperglycemia may induce diabetes complications. Hesperetin, a bioflavonoid, is a glycoside in citrus fruits and is known to have antioxidant and anticarcinogenic properties. However,...
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Polymorphisms of Ionotropic Glutamate Receptor-Related Genes and the Risk of Autism Spectrum Disorder in a Chinese Population

Xie X, Hou F, Li L, Chen Y, Liu L, Luo X, Gu H, Li X, Zhang J, Gong J, Song R

OBJECTIVE: To evaluate the association of GRIK2 and NLGN1 with autism spectrum disorder in a Chinese population. METHODS: We performed spatio-temporal expression analysis of GRIK2 and NLGN1 in the developing prefrontal...
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A Novel Effect of Lipids Extracted from Vernix Caseosa on Regulation of Filaggrin Expression in Human Epidermal Keratinocytes

Qiao W, Jia T, Gu H, Guo R, Kaku K, Wu W

BACKGROUND: Vernix caseosa (VC), which is known as a unique human substance, is a biofilm that covers the skin of most human newborns. VC has many biological functions including anti-infective,...
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Tryptophan Metabolites in Irritable Bowel Syndrome: An Overnight Time-course Study

Burr RL, Gu H, Cain K, Djukovic D, Zhang X, Han C, Callan N, Raftery D, Heitkemper M

  • KMID: 2460485
  • J Neurogastroenterol Motil.
  • 2019 Oct;25(4):551-562.
  • doi: 10.5056/jnm19042
BACKGROUND/AIMS: Patients with irritable bowel syndrome (IBS) often report poor sleep quality. Whether poor sleep is associated with tryptophan (Trp) metabolites is unknown. We compared serum Trp metabolites in women...
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Therapy-related acute promyelocytic leukemia in plasma cell myeloma treated with melphalan: a case report and literature review

Gu H, Kim YJ, Lee WI, Lee J, Yoon HJ, Park TS

No abstract available.
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Five Cases of the Gram Variable Bacterium Paenibacillus urinalis Isolated from Clinical Specimens and its Clinical Significance

Gu H, Kim YJ, Ryu J, Cho SY, Lee HJ

Paenibacillus urinalis was first isolated from the urine of a woman in 2008, and was reported to be a contaminant. Here, we report 5 cases of P. urinalis isolated over...
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Estrogenic activity of zinc pyrithione: an in vivo and in vitro study

Yoon KS, Youn N, Gu H, Kwack SJ

Zinc pyrithione (ZP) is commonly used to prevent dandruff and seborrheic dermatitis. Many consumers are exposed daily to high doses of ZP, causing serious concerns about its toxicity. The reproductive...
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Erratum: Current View of Orphan Drug Usage in Tertiary Hospital and Rare Incurable Disease Hospital

Choi KS, Jeong YM, Kim YJ, Kim YH, Gu H, Lee BK, Lee E, Rhie SJ

Erratum agreed to by all authors, editor in chief, publisher, and scientific society.
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Current View of Orphan Drug Usage in Tertiary Hospital and Rare Incurable Disease Hospital

Choi KS, Jeong YM, Kim YJ, Kim YH, Gu H, Lee BK, Lee E, Rhie SJ

OBJECTIVE: Until now, there is minimal number of research for overall domestic status of orphan drug use in Korea. The purpose of this study is to identify the list of...
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Angiopoietin-1 and Angiopoietin-2 Expression Imbalance Influence in Early Period After Subarachnoid Hemorrhage

Gu H, Fei ZH, Wang YQ, Yang JG, Zhao CH, Cai Y, Zhong XM

PURPOSE: Microvascular endothelial integrity is important for maintaining the blood-brain barrier (BBB). However, subarachnoid hemorrhage (SAH) disrupts this integrity, making the BBB dysfunctional—an important pathophysiological change after SAH. Angiopoietin-1 (Ang-1)...
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Usefulness of Bardach's Technique for Secondary Correction of Cleft Lip Nasal Deformity

Ryu SY, Gu H, Yang JW

  • KMID: 2044714
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2010 Sep;32(5):406-415.
PURPOSE: The secondary correction of cleft lip nasal deformity still presents a difficult surgical problems. The present study was aimed to investigate the usefulness of Bardach's technique for secondary correction...
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Effects of pterygomaxillary separation on skeletal and dental changes following surgically-assisted rapid maxillary expansion

Han IH, An JS, Gu H, Kook MS, Park HJ, Oh HK

  • KMID: 2400584
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2006 Jul;28(4):320-328.
PURPOSE: The aim of this study was to evaluate the effects of pterygomaxillary separation on dimensional changes of dental arch following surgically-assisted rapid maxillary expansion (SARME). PATIENTS AND METHODS: Eighteen adults...
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The effect of location and angle of drilling on the changes of the distance between two block specimens during screwing on miniplate fixation

Oh HC, An JS, Gu H, Kook MS, Park HJ, Oh HK

  • KMID: 1960519
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2006 May;28(3):213-221.
PURPOSE: This study was aimed to evaluate the effect of the location and angle of drilling on the changes of the distance between the two block specimens. MATERIALS AND METHODS: In...
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The study by using the computerized tomography imaging in order to access to mandibular foramen while inferior alveolar nerve anesthesia

Kim JK, Gu H, An JS, Kook MS, Park HJ, Oh HK, Cho JH

  • KMID: 2328401
  • J Korean Assoc Oral Maxillofac Surg.
  • 2006 Dec;32(6):566-574.
PURPOSE: This study was performed to provide an anatomical information of the mandibular ramus for the successful inferior alveolar nerve block. Three dimensional images were reconstructed from the computerized tomography...
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The study of evaluation to relationship between the inferior alveolar nerve and the mandibular third molar by using radiographic image

Kim JH, Gu H, An JS, Kook MS, Park HJ, Oh HK

  • KMID: 1961040
  • J Korean Assoc Oral Maxillofac Surg.
  • 2006 Oct;32(5):464-473.
PURPOSE: This study was performed to evaluate relationship between the inferior alveolar nerve injury and the findings of panoramic and tomographic images for preventing inferior alveolar nerve injury after the...
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A modified endaural and neck approach to the parotid gland tumor

Ryu SY, Kook MS, Kim SK, Han CH, Gu H, Kwon JK, An JS

  • KMID: 1575882
  • J Korean Assoc Oral Maxillofac Surg.
  • 2005 Dec;31(6):501-508.
Generally we use the preauricular incision to access and remove the parotid gland tumor. But the preauricular approach has some complications such as damage of facial nerve and sensory nerve,...
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A Case of Juvenile Dermatomyositis

Yom HW, Park JH, Seo JW, Choi HY, Gu H, Lee SW, Kang YJ

  • KMID: 2329308
  • J Korean Child Neurol Soc.
  • 2003 May;11(1):178-183.
Juvenile dermatomyositis is an uncommon autoimmune disease with classic heliotrope discoloration of eyelids, erythematous skin rash of joints and proximal muscle weakness. Quite different from adults, malignancy is rarely accompanied...
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Arthroscopic Reduction of Bony Avusion of the Posterior Cruciate Ligament from the Tibia using Pull-out PDS

Lee Y, Kim Y, Joh B, Gu H

  • KMID: 2064695
  • J Korean Knee Soc.
  • 1998 Dec;10(2):258-262.
No abstract available.
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