- Cyclic AMP prolongs graft survival by suppressing apoptosis and inflammatory gene expression in acute cardiac allograft rejection
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Lee JY, Kim JH, Chae G, Lee BK, Ha KS, Kwon YG, Kim YM
- KMID: 946671
- Exp Mol Med.
- 2010 Jan;42(1):69-79.
- doi: 10.3858/emm.2010.42.1.008
This study was designed to investigate the effects of cAMP on immune regulation and apoptosis during acute rat cardiac allograft rejection. We found that the production of immune markers such... -
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- Prolonged survival of islet allografts in mice treated with rosmarinic acid and anti-CD154 antibody
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Jung DY, Kim EY, Joo SY, Park JB, Moon C, Kim SH, Sim EY, Joh JW, Kwon CH, Kwon GY, Kim SJ
- KMID: 1103582
- Exp Mol Med.
- 2008 Feb;40(1):1-10.
- doi: 10.3858/emm.2008.40.1.1
Pancreatic islet transplantation can correct the abnormal glucose metabolism of Type 1 diabetes. Although immunosuppressants greatly reduce the acute rejection rate in transplant patients, the long-term side effects can be... -
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- Colchicine-derived compound CT20126 promotes skin allograft survival by regulating the balance of Th1 and Th2 cytokine production
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Lee SJ, Namkoong S, Ha KS, Nam WD, Kwon YG, Lee H, Yoon EY, Chang DJ, Kim SO, Kim YM
- KMID: 1094664
- Exp Mol Med.
- 2007 Apr;39(2):230-238.
Colchicine has been shown to regulate the expression of inflammatory gene, but this compound possesses much weaker anti-inflammatory activity. In this study, we synthesized a new colchicine derivative CT20126 and... -
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- The Role of Cyclosporine and Mycophenolate in an Orthotopic Porcine-to-Rat Corneal Xenotransplantation
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Lee HI, Kim MK, Oh JY, Ko JH, Lee HJ, Wee WR, Lee JH
- KMID: 1786890
- J Korean Med Sci.
- 2008 Jun;23(3):492-501.
- doi: 10.3346/jkms.2008.23.3.492
We performed this study to investigate the feature of rejection in porcine-to-rat corneal orthotopic transplantation and to evaluate the effect of cyclosporine and mycophenolate on the xeno-rejection. Orthotopic corneal transplantation... -
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- Short-term Efficacy of Topical Immunosuppressive Agents on the Survival of Cultivated Allo-Conjunctival Equivalents
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Shin YJ, Kim MK, Oh JY, Wee WR, Lee JH, Ko JH, Lee HJ, Lee JL, Min BM, Sohn YS
- KMID: 1099007
- Korean J Ophthalmol.
- 2008 Jun;22(2):123-129.
- doi: 10.3341/kjo.2008.22.2.123
PURPOSE: To investigate the short-term efficacy of topical immunosuppressive agents on the survival of cultivated allo-conjunctival equivalents. METHODS: Twenty-five eyes of New Zealand white rabbits were included. Temporal... -
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