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Ovarian Stromal Hyperplasia: A Rare Cause of Postmenopausal Hyperandrogenism

Araque TL, Ortiz IRM, González J, García AJ, Hidalgo IN, Gamarra VA, Soler CP, Raga FG

Ovarian hyperthecosis and ovarian stromal hyperplasia (OSH) are two uncommon non-neoplastic causes of ovarian hyperandrogenism, whose etiology is still unknown. These conditions are characterized by obesity, hyperinsulinemia, acanthosis nigricans, and...
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Osborne-Cotterill Lesion a Forgotten Injury: Review Article and Case Report

Vargas DG, Woodcock S, Porto GF, Gonzalez J

Osborne-Cotterill lesion is an osteochondral fracture located in the posterolateral margin of the humeral capitellum, which may be associated with a defect of the radial head after an elbow dislocation....
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Role of Endoscopy in the Management of Boerhaave Syndrome

Tellechea , Gonzalez J, Miranda-García P, Culetto A, D'Journo X, Thomas PA, Barthet M

Boerhaave syndrome (BS) is a spontaneous esophageal perforation which carries high mortality. Surgical treatment is well established, but the development of interventional endoscopy has proposed new therapies. We expose our...
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Effects of D-003 (10 mg/day) on Bone Mineral Density of the Lumbar Spine and Femoral Neck in Postmenopausal Women: A Randomized, Double-Blinded Study

Ceballos A, Castano G, Mendoza S, Gonzalez J, Mas R, Fernandez , Illnait J, Mesa M, Gamez R, Fernandez , Telles R, Marrero D, Eng MG, Ruiz D, Jardines Y

BACKGROUND/AIMS: Increased osteoclast activity is a pivotal finding in osteoporosis. This increase is mediated via the mevalonate-to-cholesterol pathway, which is involved in producing the intermediates required for osteoclast activity. D-003,...
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Comparison of the Effects of Ezetimibe-Statin Combination Therapy on Major Adverse Cardiovascular Events in Patients with and without Diabetes: A Meta-Analysis

Hong N, Lee YH, Tsujita K, Gonzalez J, Kramer CM, Kovarnik T, Kouvelos G, Suzuki H, Han K, Lee CJ, Park SH, Lee BW, Cha BS, Kang ES

BACKGROUND: Ezetimibe-statin combination therapy has been found to reduce low density lipoprotein cholesterol levels and the risk of major adverse cardiovascular events (MACEs) in large trials. We sought to examine...
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