- Increased glycosylation of human lens epithelial basement membrane in diabetes mellitus
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Shin DH, Mandel SS, Lee JH, Ernst B, Newman BL, Juzych M
- KMID: 1735118
- Korean J Ophthalmol.
- 1994 Jun;8(1):26-31.
- doi: 10.3341/kjo.1994.8.1.26
We studied the nonenzymatic glycosylation of lens epithelial basement membranes (LEBM) of senile cataractous lenses of both diabetic and nondiabetic patients. The human LEBMs were isolated from surgically removed senile... -
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- Computational Approach for the Analysis of Post-PKS Glycosylation Step
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Kim KB, Park K
- KMID: 2166422
- Genomics Inform.
- 2008 Dec;6(4):223-226.
We introduce a computational approach for analysis of glycosylation in Post-PKS tailoring steps. It is a computational method to predict the deoxysugar biosynthesis unit pathway and the substrate specificity of... -
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- Glycosylation of Human Lens Capsule(Basement Membrane) Protein in Diabetes Mellitus
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Baek NH
- KMID: 2336403
- J Korean Ophthalmol Soc.
- 1987 Apr;28(2):327-332.
Human lens capsules(basement membrane of lens epithelium) were isolated from surgically removed cataractous lenses of diabetic and nondiabetic patients with senile cataracts. Basement membranes were purified from lens capsules, using... -
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- A Simplified Colorimetric Assay of Nonenzymatic Glycosylation of Human low Density Lipoproteins in Normal and Diabetes Mellitus
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Hahm KS, Park KK, Kim YS
- KMID: 693009
- Yonsei Med J.
- 1986 Mar;27(1):7-16.
- doi: 10.3349/ymj.1986.27.1.7
A simplified colorimetric method for measurement of the levels of glycosylation of proteins was developed by a modification of an existing method. Employing this method, the extent of nonenzymatic glycosylation... -
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- Impact of glycosylation on the unimpaired functions of the sperm
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Cheon YP, Kim CH
- KMID: 2069031
- Clin Exp Reprod Med.
- 2015 Sep;42(3):77-85.
- doi: 10.5653/cerm.2015.42.3.77
One of the key factors of early development is the specification of competence between the oocyte and the sperm, which occurs during gametogenesis. However, the starting point, growth, and maturation... -
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- Letter: The Association between Serum Endogenous Secretory Receptor for Advanced Glycation End Products and Vertebral Fractures in Type 2 Diabetes (Endocrinol Metab 2012;27:289-94, Cheol Ho Lee et al.)
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Hwang YC
- KMID: 1805951
- Endocrinol Metab.
- 2013 Mar;28(1):76-77.
- doi: 10.3803/EnM.2013.28.1.76
No abstract available. -
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- The anti-tumor mechanisms of p53 through the regulation of expression and glycosylation of insulin-like growth factor binding protein-3
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Kim SY, Kim SR, Lee JC, Yi HK, Lee DY, Hwang PH
- KMID: 2140910
- Korean J Pediatr.
- 2006 Apr;49(4):431-438.
- doi: 10.3345/kjp.2006.49.4.431
PURPOSE: Insulin-like growth factor binding protein(IGFBP)-3 has been known as a tumor suppressor gene, and its anti-tumor function was divided into insulin-like growth factor(IGF)-dependent and IGF-independent mechanism. In IGF-independent mechanism,... -
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- Response: The Association between Serum Endogenous Secretory Receptor for Advanced Glycation End Products and Vertebral Fractures in Type 2 Diabetes (Endocrinol Metab 2012;27:289-94, Cheol Ho Lee et al.)
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Lee CH, Lee MK, Han HJ, Kim TH, Lee JH, Kim SH
- KMID: 1805952
- Endocrinol Metab.
- 2013 Mar;28(1):78-79.
- doi: 10.3803/EnM.2013.28.1.78
No abstract available. -
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- An antibody reactive to the Gly63-Lys68 epitope of NT-proBNP exhibits O-glycosylation-independent binding
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Lee Y, Kim H, Chung J
- KMID: 2155379
- Exp Mol Med.
- 2014 Sep;46(9):e114.
- doi: 10.1038/emm.2014.57
The N-terminal fragment of prohormone brain natriuretic peptide (NT-proBNP) is a commonly used biomarker for the diagnosis of congestive heart failure, although its biological function is not well known. NT-proBNP... -
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- Mac-2 Binding Protein Glycosylation Isomer: Emerging Non-Invasive Serum Marker for Liver Fibrosis
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Cho SY, Hur M
- KMID: 2408066
- Ann Lab Med.
- 2018 Jul;38(4):289-290.
- doi: 10.3343/alm.2018.38.4.289
No abstract available. -
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- Production of Recombinant Anti-Cancer Vaccines in Plants
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Lee JH, Ko K
- KMID: 2386899
- Biomol Ther.
- 2017 Jul;25(4):345-353.
- doi: 10.4062/biomolther.2016.126
Plant expression systems have been developed to produce anti-cancer vaccines. Plants have several advantages as bioreactors for the production of subunit vaccines: they are considered safe, and may be used... -
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- Glyceraldehyde-Derived Advanced Glycation End Products Accumulate Faster Than N(ε)-(Carboxymethyl) Lysine
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Yokota M, Sekita M, Okano Y, Masaki H, Takeuchi M, Tokudome Y
- KMID: 2388959
- Ann Dermatol.
- 2017 Aug;29(4):508-511.
- doi: 10.5021/ad.2017.29.4.508
No abstract available. -
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- N-Linked Glycosylation in the Hemagglutinin of Influenza A Viruses
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Kim JI, Park MS
- KMID: 2453944
- Yonsei Med J.
- 2012 Sep;53(5):886-893.
Since the 1918 influenza A virus (IAV) pandemic, H1N1 viruses have circulated in human populations. The hemagglutinin (HA) of IAV determines viral antigenicity and often undergoes N-linked glycosylation (NLG) at... -
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- Collagen Changes of the Corpus Cavernosum in Streptozotocin-Induced Diabetic Rats and the Effects of Insulin and Aminoguanidine
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Kim KS, Hong JH, Ahn TY
- KMID: 1614929
- Korean J Androl.
- 2001 Apr;19(1):35-39.
PURPOSE: Diabetes changes the properties of collagen in our body tissue, increasing cross-linked collagen via nonenzymatic glycosylation and accumulation of advanced glycosylation end products. Glucose-derived cross-linked collagen formation may contribute... -
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- Biological Meaning of the Histo-Blood Group Antigens Composed of Sugar Chains
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Kwon SW, Ahn A, Chung Y
- KMID: 2255807
- Korean J Blood Transfus.
- 2015 Aug;26(2):103-122.
- doi: 10.17945/kjbt.2015.26.2.103
All living creatures on this planet, from bacteria to human, produce sugar chains (glycans). This means that sugar chains are essential for living a life. Abundant, diverse, and highly regulated... -
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- The Role of Advanced Glycation End Products in Diabetic Vascular Complications
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Rhee SY, Kim YS
- KMID: 2413980
- Diabetes Metab J.
- 2018 Jun;42(3):188-195.
- doi: 10.4093/dmj.2017.0105
In cases of chronic hyperglycemia, advanced glycation end-products (AGEs) are actively produced and accumulated in the circulating blood and various tissues. AGEs also accelerate the expression of receptors for AGEs,... -
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- Identification and characterization of buckwheat allergen
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Jeoung BJ, Ryu JW, Yum HY, Kim KE, Park JW, Hong CS, Lee KY
- KMID: 2286078
- J Asthma Allergy Clin Immunol.
- 1999 Feb;19(1):62-66.
BACKGROUND AND OBJECTIVE: Buckwheat is considered one of the most important food allergens in Korea. Although a very small amount is ingested or inhaled, it can cause serious allergic reactions. However, the... -
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- Endoplasmic reticulum stress (ER-stress) by 2-deoxy-D-glucose (2DG) reduces cyclooxygenase-2 (COX-2) expression and N-glycosylation and induces a loss of COX-2 activity via a Src kinase-dependent pathway in rabbit articular chondrocytes
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Yu SM, Kim SJ
- KMID: 994401
- Exp Mol Med.
- 2010 Nov;42(11):777-786.
- doi: 10.3858/emm.2010.42.11.079
Endoplasmic reticulum (ER) stress regulates a wide range of cellular responses including apoptosis, proliferation, inflammation, and differentiation in mammalian cells. In this study, we observed the role of 2-deoxy-D-glucose (2DG)... -
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- Ginseng Total Saponin Improves Podocyte Hyperpermeability Induced by High Glucose and Advanced Glycosylation Endproducts
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Ha TS, Choi JY, Park HY, Lee JS
- KMID: 1785989
- J Korean Med Sci.
- 2011 Oct;26(10):1316-1321.
- doi: 10.3346/jkms.2011.26.10.1316
Early diabetic nephropathy is characterized by glomerular hyperpermeability as a result of impaired glomerular filtration structure caused by hyperglycemia, glycated proteins or irreversible advanced glycosylation endproducts (AGE). To investigate the... -
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- Serum Glycosylated Albumin and Fructosamine in Patients with Chronic Renal Failure Undergoing Dialysis
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Cho HS, Lee MH
- KMID: 2254676
- Korean J Nephrol.
- 1998 Mar;17(2):275-281.
Glucose intolerance commonly occurs in patients with renal failure undergoing hemodialysis. whether this mild glucose intolerance contributes to pathogenesis of uremic complication in unknown. Abnormally elevated levels of Hb A1... -
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