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Assessment of the Glycophorin A Mutant Assay as a Biologic Marker for Low Dose Radiation Exposure

Ha M, Yoo KY, Ha SW, Kim DH, Cho SH

  • KMID: 2283147
  • Korean J Prev Med.
  • 2000 Jun;33(2):165-173.
OBJECTIVES: To assess the availability of the glycophorin A (GPA) assay to detect the biological effect of ionizing radiation in workers exposed to low-doses of radiation. METHODS: Information on confounding factors,...
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Isolation of Fetal Cell from Maternal Blood by Glycophorin A[GPA] Staining and Microdissection

Moon JS, Jeong JH, Oh JM, Hwang JD, Yang SH, Roh JR, Song SY, Kim SW, Lee JH

  • KMID: 2269609
  • Korean J Obstet Gynecol.
  • 1999 May;42(5):1048-1054.
OBJECTIVE: Fetal cells in maternal circulation offer a potential source of fetal informations by noninvasive procedure. As there is no completely selective method to separate fetal cells from...
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Arsenic Trioxide Induces Erythroid Differentiation and Apoptosis of K562 Human Leukemia Cells through the Down-Regulation of Bcl-2

You YK, Cheong HJ, Won JH, Kim SJ, Bae SB, Kim CK, Lee NS, Lee KT, Park SK, Hong DS, Park HS

BACKGROUND: Arsenic trioxide (As2O3) has been identified as an effective drug for the treatment of acute promyelocytic leukemia (APL). However, the role of As2O3 during the erythroid differentiation of human...
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Enforced Expression of BMI-1 in Postnatal Human CD34+ Cells Promotes Erythroid Differentiation

Lee G, Kim BS, Shieh JH, Moore MA

BACKGROUND: The Polycomb-group gene Bmi-1 is known to be a molecular regulator of self-renewal of normal and leukemic stem cells and be involved in various aspects of cellular proliferation, differentiation,...
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Proliferation and Differentiation of Erythroid Progenitors from Cord Blood CD34 (+) Cells Using Extracellular Matrix and Stromal Cells

Choi HS, Koh SH, Park ES, Kang HJ, Shin HY, Ahn HS

  • KMID: 2278273
  • Korean J Pediatr Hematol Oncol.
  • 2003 Apr;10(1):82-90.
PURPOSE: This study was performed to induce proliferation and differentiation of erythroid progenitors from cord blood CD34 cells using extracellular matrix (ECM) and stromal cells. METHODS: Cord blood mononuclear cells...
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A Case of Polyagglutination due to T Activation

Kim HO, Kim JJ, Choi SS

  • KMID: 2253863
  • Korean J Blood Transfus.
  • 1996 Dec;7(2):263-268.
Red blood cells that agglutinate with most normal adult sera but never with own sera are termed polyagglutinable and can be separated by patterns of lectin reactivity into various types....
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Obstetrical Outcomes of Increased Nucleated RBC in Maternal Blood during Early Pregnancy

Song GA, Lee SH, Baek DH, Je GH, Han JY

  • KMID: 2262412
  • Korean J Obstet Gynecol.
  • 2001 Oct;44(10):1817-1822.
OBJECTIVE: During early pregnancy, CD71 and glycophorin A positive cells in peripheral blood of pregnant women were studied, to assess the relationship between increased numbers of nucleated RBC (NRBC) in...
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Ex Vivo Generation of RBCs from CD34+ Cells in Human Umbilical Cord Blood and Expression Profile Analysis Using Microarray

Kim CK, Rhee J, Park KI, Kim HS, Lyu CJ, Rha SY, Kim HO

  • KMID: 2305431
  • Korean J Lab Med.
  • 2005 Dec;25(6):457-464.
BACKGROUND: In this study, we attempted to generate RBCs from CD34+ cells in cord blood using a 3-step culture protocol and also evaluated a change in immunophenotypic characteristics and expression...
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Quantitative Analysis of Cultured Erythroid Progenitors in Liquid System

Han JY, Kim TG, Kim KH, Kim AS, Bae HR, Suh DJ, Kang SM, Park JI, Kim IH

  • KMID: 2083350
  • Korean J Hematol.
  • 1997 May;32(1):32-40.
BACKGROUND: Hemopoiesis and erythropoiesis have been studied mainly in immortalized cell lines and semisolid medium. But cell lines do not represent normal erythropoiesis, besides, in semisolid medium the cells are...
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Role of Gamma Globin Promoter Region -269~-240 in Hydroxyurea Treated Erythroid Progenitor Cells

Park JI, Kim TG, Kim DI, Kim IH, Jeong JS, Han JY

  • KMID: 1863286
  • Korean J Clin Pathol.
  • 1998 Mar;18(1):29-34.
BACKGROUND: Recently, a great deal of interest has been focused on the use of hydroxyurea and hemin that may augment Hb F levels in patients with hemoglobinopathies and thalassemia, although...
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Erythroleukemic Blast Crisis of Chronic Myeloid Leukemia

Chung HJ, Chi HS, Seo EJ, Jang S, Park CJ, Lee KH

Erythroleukemic blast crisis of chronic myeloid leukemia (CML) is very rare. We report two cases of erythroleukemic blast crisis of CML resistant to imatinib treatment. Both patients made a rapid...
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The First Korean Case Report of Anti-Gerbich

Jeon YL, Park TS, Cho SY, Oh SH, Kim MH, Kang SY, Lee WI

  • KMID: 2434488
  • Ann Lab Med.
  • 2012 Nov;32(6):442-444.
In this study, we report the first Korean case of an anti-Gerbich (Ge) alloantibody to a high-incidence antigen that belongs to the Ge blood group system. The alloantibody was detected...
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Prenatal genetic diagnosis from maternal blood: simultaneous immunophenotyping and FISH of fetal nucleated erythrocytes isolated by negative and positive magnetic activated cell sorting

Yang YH, Jee KJ, Kim SK, Park YW, Kim IK, Cha DH, Chung JE, Kim SH

Fetal nucleated red blood cells (nRBCs) are rare in maternal circulation, but their presence constitutes a potential source of non-invasive prenatal genetic diagnosis. This study was undertaken to establish a...
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