- Estrogen receptor 1, Glutathione S-transferase P1, Glutathione S-transferase M1, and Glutathione S-transferase T1 Genes with Dysmenorrhea in Korean Female Adolescents
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Woo HY, Kim KH, Lim SW
- KMID: 1096823
- Korean J Lab Med.
- 2010 Feb;30(1):76-83.
- doi: 10.3343/kjlm.2010.30.1.76
BACKGROUND: Dysmenorrhea is the most common gynecologic complaint among adolescent females. We investigated the association between genetic polymorphisms and dysmenorrhea. METHODS: A total of 202 postmenarcheal Korean female adolescents 16-17... -
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- GSTM1, GSTT1 and GSTP1 Polymorphisms in the Korean Population
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Cho HJ, Lee SY, Ki CS, Kim JW
- KMID: 2157771
- J Korean Med Sci.
- 2005 Dec;20(6):1089-1092.
- doi: 10.3346/jkms.2005.20.6.1089
The isoenzymes of the glutathione s transferase (GST) family play a vital role in phase II of biotransformation of many substances. Using a multiplex polymerase chain reaction and a direct... -
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- Association between Glutathione S-Transferase T1, M1, and P1 Genotypes and the Risk of Colorectal Cancer
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Cong N, Liu L, Xie Y, Shao W, Song J
- KMID: 2069929
- J Korean Med Sci.
- 2014 Nov;29(11):1488-1492.
- doi: 10.3346/jkms.2014.29.11.1488
Glutathione S-transferases (GSTs) are enzymes which play an important role in the neutralization of toxic compounds and eradication of electrophilic carcinogens. Genetic polymorphisms within the genes encoding for GSTs may... -
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- Benzo[a]pyrene-Induced DNA-Protein Crosslinks in Cultured Human Lymphocytes and the Role of the GSTM1 and GSTT1 Genotypes
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Park HS, Ha EH, Lee KH, Hong YC
- KMID: 1101544
- J Korean Med Sci.
- 2002 Jun;17(3):316-321.
- doi: 10.3346/jkms.2002.17.3.316
We investigated the influence of glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) polymorphisms upon DNA-protein crosslinks (DPC) induced by benzo[a]pyrene (B[a]P) in cultured human lymphocytes. Lymphocyte samples were... -
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- GSTM1 Tissue Genotype as a Recurrence Predictor in Non-muscle Invasive Bladder Cancer
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Ha YS, Yan C, Jeong P, Kim WT, Yun SJ, Yi Kim I, Moon SK, Kim WJ
- KMID: 1782111
- J Korean Med Sci.
- 2011 Feb;26(2):231-236.
- doi: 10.3346/jkms.2011.26.2.231
Tissue genotyping is more useful approach than using blood genomic DNA, which can reflect the effects of the somatic mutations in cancer. Although polymorphisms in glutathione S-transferase (GST) have been... -
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- GSTM1 and GSTP1 Polymorphisms as Potential Factors for Modifying the Effect of Smoking on Inflammatory Response
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Kim JH, Park SG, Lee KH, Choi JH, Ha EH, Myung SK, Hong YC
- KMID: 1713112
- J Korean Med Sci.
- 2006 Dec;21(6):1021-1027.
- doi: 10.3346/jkms.2006.21.6.1021
Inflammation has been known to be an important underlying condition for development of various diseases including cancer. The aims of this study were to investigate whether tobacco smoke exposure increases... -
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- Impact of Glutathione S-Transferase M1 and T1 Gene Polymorphisms on the Smoking-Related Coronary Artery Disease
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Kim SJ, Kim MG, Kim KS, Song JS, Yim SV, Chung JH
- KMID: 1786870
- J Korean Med Sci.
- 2008 Jun;23(3):365-372.
- doi: 10.3346/jkms.2008.23.3.365
Glutathione S-transferase (GST) plays a key role in the detoxification of xenobiotic atherogen generated by smoking. To analyze the effect of GSTM1/T1 gene polymorphisms on the development of smoking-related coronary... -
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- Glutathione S-Transferase M1 Status and Breast Cancer Risk: A Meta-Analysis
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Sull JW, Ohrr H, Kang DR, Nam CM
- KMID: 721421
- Yonsei Med J.
- 2004 Aug;45(4):683-689.
- doi: 10.3349/ymj.2004.45.4.683
It is not yet clear whether Glutathione S-transferase M1 (GSTM1) polymorphisms affect the risk of breast cancer. The aim of this study is to provide a comprehensive meta-analysis of all... -
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- GSTP1 Polymorphism, Cigarette Smoking and Cervical Cancer Risk in Korean Women
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Jee SH, Lee JE, Kim S, Kim JH, Um SJ, Lee SJ, Namkoong S, Park JS
- KMID: 1093945
- Yonsei Med J.
- 2002 Dec;43(6):712-716.
- doi: 10.3349/ymj.2002.43.6.712
Previous studies have suggested that glutathione S-transferase (GST) genotypes may play a role in determining susceptibility to cervical cancer, though the data have often been conflicting. The objective of this... -
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- Glutathione S-transferases (GSTM1, GSTT1 and GSTP1) and N-acetyltransferase 2 Polymorphisms and the Risk of Gastric Cancer
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Hong SH, Kim JW, Kim HG, Park IK, Ryoo JW, Lee CH, Sohn YK, Lee JY
- KMID: 792400
- J Prev Med Public Health.
- 2006 Mar;39(2):135-140.
OBJECTIVES: Polymorphisms of genes from glutathione Stransferases (GSTs) and N-acetyltransferase 2 (NAT2) have been associated with increased susceptibility to various cancers. Previous results showed that East Asians such as... -
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- Polymorphisms of CYP1A1 and GSTM1 Genes and Susceptibility to Oral Cancer
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Cha IH, Park JY, Chung WY, Choi MA, Kim HJ, Park KK
- KMID: 1779525
- Yonsei Med J.
- 2007 Apr;48(2):233-239.
- doi: 10.3349/ymj.2007.48.2.233
PURPOSE: Oral cancer is the fifth most common form of cancer in the world and comprises 6.5% of all cancer deaths. Since one of the major risk factors for oral... -
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