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A Case of Gilbert's Syndrome with Severe Neonatal Hyperbilirubinemia

Hong YS, Jin JY, Lee WR

  • KMID: 2321501
  • J Korean Soc Neonatol.
  • 2010 Nov;17(2):266-269.
Gilbert's syndrome is caused by a reduction in the activity of uridine diphosphate glucuronosyltransferase (UGT) and induces chronic, non-hemolytic unconjugated hyperbilirubinemia. It has been suggested that 3-10% of the population...
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Coexistence of Gilbert Syndrome and Hereditary Spherocytosis in a Child Presenting with Extreme Jaundice

Lee JH, Moon KR

Gilbert syndrome is the most common inherited disorder of bilirubin glucuronidation. It is characterized by intermittent episodes of jaundice in the absence of hepatocellular disease or hemolysis. Hereditary spherocytosis is...
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A Study of Polymorphism in UDP-glucuronosyltransferase 1 (UGT-1A1) Promoter Gene in Korean Patients with Gilbert's Syndrome

Kim YH, Yeon JE, Jung GM, Kim HJ, Kim JS, Byun KS, Bak YT, Lee CH

  • KMID: 1123162
  • Korean J Hepatol.
  • 2002 Jun;8(2):132-138.
BACKGROUNDS/AIMS: Hepatic glucuronidating activity, essential for efficient biliary excretion of bilirubin, is reduced to about 30 percent of normal in patients with Gilbert's syndrome. Patients with Gilbert's syndrome have an...
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A Case of Congenital Hemolytic Anemia of Unknown Cause Combined with Gilbert's Syndrome

Lim JW, Choi JH, Nam YH, Seo IS, Yoon SM, Koo MS

Congenital hemolytic anemia is mainly developed due to intrinsic defects of erythrocytes, but in some cases the cause of hemolytic anemia is unclear. Gilbert's syndrome shows mild, chronic unconjugated hyperbilirubinemia...
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A Case of Hereditary Spherocytosis Coexisting with Gilbert's Syndrome

Lee MJ, Chang YH, Kang SH, Mun SK, Kim H, Han CJ, Kim J, Kang HJ

We recently encountered a case of hereditary spherocytosis coexisting with Gilbert's syndrome. Patient was initially diagnosed with Gilbert's syndrome and observed, but other findings suggestive of concurrent hemolysis, such as...
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Severe Jaundice in Two Children with Kawasaki Disease: A Possible Association with Gilbert Syndrome

Karpathios T, Moustaki M, Yiallouros P, Sharifi F, Attilakos , Papadopoulou A, Fretzayas

Kawasaki disease is a systemic vasculitis, mainly encountered in children. It may affect any organ. Acute cholestasis and severe obstructive jaundice is an atypical manifestation of the disease. We herein...
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A case of concomitant Gilbert's syndrome and hereditary spherocytosis

Lee HJ, Moon HS, Lee ES, Kim SH, Sung JK, Lee BS, Jeong HY, Lee HY, Eu YJ

We describe moderate hyperbilirubinemia in a 28-year-old man who suffered from gallstones and splenomegaly, with combined disorders of hereditary spherocytosis (HS) and Gilbert's syndrome (GS). Since it is difficult to...
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Percutaneous Needle Liver Biopsy in Infancy and Childhood

Chung KS, Sohn YM, Yun DJ, Park CI

  • KMID: 1946076
  • J Korean Pediatr Soc.
  • 1981 Jul;24(7):609-619.
Thirty percutaneous liver biopsy and one liver necropsy were reviewed in Severance Hospital, Yonsei University from June 1979 to September 1980. This procedure is the safe and accurate means of...
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A Case of Gilberts Syndrome Combined with Hemolysis

Choi GB, Han KS, Bae WJ, Kim MK, Lee SN, Kyung NH

Gilbert's Syndrome is the name most frequently used to describe a condition which has been called constitutional heptic dysfunction, familial nonhemolytic jaundice of icterus intermittens juvenilis. It is characterized by...
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Isolated Unconjugated Hyperbilirubinemia after Liver Transplantation

Choi YR, Suh KS, Shin WY, Lee HW, Cho EH, Yi NJ, Lee KU

  • KMID: 1928360
  • Korean J Hepatobiliary Pancreat Surg.
  • 2007 Mar;11(1):42-47.
PURPOSE: In our experience, post-LT persistent isolated unconjugated hyperbilirubinemia (IUH) has been frequently observed even after liver transplantation (LT) from normal donors. The present study was performed to evaluate the...
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A case of rotor syndrome

Kim JH, Koo YS, Jeong JI, Jeong SY, Kwun DH, Shin DW, Hahn BC, Suh DJ

  • KMID: 2306223
  • Korean J Med.
  • 2000 Jul;59(1):109-113.
Rotor syndrome is a rare benign familial disorder characterized by chronic, fluctuating, nonhemolytic and predominantly conjugated hyperbilirubinemia with normal liver tissue. In contrast to Dubin-Johnson syndrome, there is no liver hyperpigmentation in...
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Diagnostic Approach to Abnormal Liver Tests in Apparently Healthy Subjects

Kim BH

Blood tests such as aminotransferases are indicators of liver cell injury not liver function, so it would be more appropriate to call them liver tests instead of liver function tests....
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The Role of Oxidative Stress in the Pathogenesis of Diabetic Vascular Complications

Sasaki S, Inoguchi T

Oxidative stress has been paid increasing attention to as an important causative factor for diabetic vascular complications. Among possible various sources, accumulating evidence has indicated that NAD(P)H oxidase may be...
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Association of direct bilirubin level with postoperative outcome in critically ill postoperative patients

Nagae M, Egi M, Kubota K, Makino S, Mizobuchi

BACKGROUND: Hyperbilirubinemia is a common postoperative complication. Elevated direct bilirubin (D-Bil) and indirect bilirubin (I-Bil) levels are related to different pathophysiologies; therefore, their associations with outcomes also differ. However, there...
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Hyperbilirubinemia Is a Significant Indicator for the Severity of Acute Appendicitis

Hong YR, Chung CW, Kim JW, Kwon CI, Ahn DH, Kwon SW, Kim SK

PURPOSE: This study aims to reveal more effective clinical or laboratory markers for the diagnosis of acute appendicitis and to score the severity based on a sufficiently large number of...
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