- Association of CACNA1C Variants with Bipolar Disorder in the Korean Population
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Kim S, Cho CH, Geum D, Lee HJ
- KMID: 2344745
- Psychiatry Investig.
- 2016 Jul;13(4):453-457.
- doi: 10.4306/pi.2016.13.4.453
OBJECTIVE: Previous studies have suggested an association between CACNA1C and susceptibility of bipolar disorder. In this study, we examined the association of CACNA1C variants with bipolar disorder in the Korean... -
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- Circadian Rhythm Hypotheses of Mixed Features, Antidepressant Treatment Resistance, and Manic Switching in Bipolar Disorder
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Lee HJ, Son GH, Geum D
- KMID: 2316293
- Psychiatry Investig.
- 2013 Sep;10(3):225-232.
Numerous hypotheses have been put forth over the years to explain the development of bipolar disorder. Of these, circadian rhythm hypotheses have gained much importance of late. While the hypothalamus-pituitary-adrenal... -
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- Functional Role of Parkin against Oxidative Stress in Neural Cells
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Hwang M, Lee JM, Kim Y, Geum D
- KMID: 2169353
- Endocrinol Metab.
- 2014 Mar;29(1):62-69.
- doi: 10.3803/EnM.2014.29.1.62
BACKGROUND: Parkinson disease (PD) is caused by selective cell death of dopaminergic neurons in the substantia nigra. An early onset form of PD, autosomal recessive juvenile parkinsonism has been associated... -
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- Heat shock protein 27 interacts with vimentin and prevents insolubilization of vimentin subunits induced by cadmium
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Lee JS, Zhang MH, Yun EK, Geum D, Kim K, Kim TH, Lim YS, Seo JS
- KMID: 1089452
- Exp Mol Med.
- 2005 Oct;37(5):427-435.
Vimentin is an intermediate filament that regulates cell attachment and subcellular organization. In this study, vimentin filaments were morphologically altered, and its soluble subunits were rapidly reduced via cadmium chloride... -
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- Bipolar Disorder Associated microRNA, miR-1908-5p, Regulates the Expression of Genes Functioning in Neuronal Glutamatergic Synapses
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Kim Y, Zhang Y, Pang K, Kang H, Park H, Lee Y, Lee B, Lee HJ, Kim WK, Geum D, Han K
- KMID: 2362826
- Exp Neurobiol.
- 2016 Dec;25(6):296-306.
- doi: 10.5607/en.2016.25.6.296
Bipolar disorder (BD), characterized by recurrent mood swings between depression and mania, is a highly heritable and devastating mental illness with poorly defined pathophysiology. Recent genome-wide molecular genetic studies have... -
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