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Association of mitochondrial haplogroup F with physical performance in korean population

Hwang IW, Kim K, Choi EJ, Jin HJ

Athletic performance is a complex multifactorial trait involving genetic and environmental factors. The heritability of an athlete status was reported to be about 70% in a twin study, and at...
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HisCoM-mimi: software for hierarchical structural component analysis for miRNA-mRNA integration model for binary phenotypes

Kim Y, Park T

To identify miRNA-mRNA interaction pairs associated with binary phenotypes, we propose a hierarchical structural component model for miRNA-mRNA integration (HisCoM-mimi). Information on known mRNA targets provided by TargetScan is used...
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Enrichment of rare alleles within epigenetic chromatin marks in the first intron

Jo SS, Choi SS

In previous studies, we demonstrated that some sites in the first intron likely regulate gene expression. In the present work, we sought to further confirm the functional relevance of first...
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Insights into the signal transduction pathways of mouse lung type II cells revealed by transcription factor profiling in the transcriptome

Ramana CV

Alveolar type II cells constitute a small fraction of the total lung cell mass. However, they play an important role in many cellular processes including trans-differentiation into type I cells...
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Advances in Serological Diagnosis of Taenia solium Neurocysticercosis in Korea

Ahn CS, Kim JG, Huh S, Kang I, Kong Y

Cysticercosis, a parasitic disease caused by Taenia solium metacestode (TsM), has a major global public health impact in terms of disability-adjusted life years. The parasite preferentially infects subcutaneous tissue, but...
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Statistical Analysis of Metagenomics Data

Calle ML

Understanding the role of the microbiome in human health and how it can be modulated is becoming increasingly relevant for preventive medicine and for the medical management of chronic diseases....
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Blood transcriptome resources of chinstrap (Pygoscelis antarcticus) and gentoo (Pygoscelis papua) penguins from the South Shetland Islands, Antarctica

Kim BM, Jeong J, Jo E, Ahn DH, Kim JH, Rhee JS, Park H

The chinstrap (Pygoscelis antarcticus) and gentoo (P. papua) penguins are distributed throughout Antarctica and the sub-Antarctic islands. In this study, high-quality de novo assemblies of blood transcriptomes from these penguins...
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Insights of window-bsed mechanism approach to visualize composite bioData point in feature spaces

Daoud M

In this paper, we propose a window-based mechanism visualization approach as an alternative way to measure the seriousness of the difference among data-insights extracted from a composite biodata point. The...
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Identification of ERBB Pathway-Activated Cells in Triple-Negative Breast Cancer

Cho SY

Intratumor heterogeneity within a single tumor mass is one of the hallmarks of malignancy and has been reported in various tumor types. The molecular characterization of intratumor heterogeneity in breast...
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Evaluation and Interpretation of Transcriptome Data Underlying Heterogeneous Chronic Obstructive Pulmonary Disease

Ham S, Oh YM, Roh TY

Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease, featured by airflow obstruction. Recently, a comprehensive analysis of the transcriptome in lung tissue of COPD patients was...
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In this issue, there are 10 articles: two review articles, six original articles, one clinical genomics, and one application note

Park T

No abstract available.
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