- In this issue, there are 10 articles: two review articles, six original articles, one clinical genomics, and one application note
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Park T
- KMID: 2447791
- Genomics Inform.
- 2019 Mar;17(1):e1.
- doi: 10.5808/GI.2019.17.1.e1
No abstract available. -
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- Identification of ERBB Pathway-Activated Cells in Triple-Negative Breast Cancer
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Cho SY
- KMID: 2447793
- Genomics Inform.
- 2019 Mar;17(1):e3.
- doi: 10.5808/GI.2019.17.1.e3
Intratumor heterogeneity within a single tumor mass is one of the hallmarks of malignancy and has been reported in various tumor types. The molecular characterization of intratumor heterogeneity in breast... -
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- Statistical Analysis of Metagenomics Data
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Calle ML
- KMID: 2447796
- Genomics Inform.
- 2019 Mar;17(1):e6.
- doi: 10.5808/GI.2019.17.1.e6
Understanding the role of the microbiome in human health and how it can be modulated is becoming increasingly relevant for preventive medicine and for the medical management of chronic diseases.... -
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- Insights of window-bsed mechanism approach to visualize composite bioData point in feature spaces
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Daoud M
- KMID: 2447794
- Genomics Inform.
- 2019 Mar;17(1):e4.
- doi: 10.5808/GI.2019.17.1.e4
In this paper, we propose a window-based mechanism visualization approach as an alternative way to measure the seriousness of the difference among data-insights extracted from a composite biodata point. The... -
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- Enrichment of rare alleles within epigenetic chromatin marks in the first intron
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Jo SS, Choi SS
- KMID: 2447799
- Genomics Inform.
- 2019 Mar;17(1):e9.
- doi: 10.5808/GI.2019.17.1.e9
In previous studies, we demonstrated that some sites in the first intron likely regulate gene expression. In the present work, we sought to further confirm the functional relevance of first... -
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- HisCoM-mimi: software for hierarchical structural component analysis for miRNA-mRNA integration model for binary phenotypes
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Kim Y, Park T
- KMID: 2447800
- Genomics Inform.
- 2019 Mar;17(1):e10.
- doi: 10.5808/GI.2019.17.1.e10
To identify miRNA-mRNA interaction pairs associated with binary phenotypes, we propose a hierarchical structural component model for miRNA-mRNA integration (HisCoM-mimi). Information on known mRNA targets provided by TargetScan is used... -
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- Insights into the signal transduction pathways of mouse lung type II cells revealed by transcription factor profiling in the transcriptome
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Ramana CV
- KMID: 2447798
- Genomics Inform.
- 2019 Mar;17(1):e8.
- doi: 10.5808/GI.2019.17.1.e8
Alveolar type II cells constitute a small fraction of the total lung cell mass. However, they play an important role in many cellular processes including trans-differentiation into type I cells... -
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- Evaluation and Interpretation of Transcriptome Data Underlying Heterogeneous Chronic Obstructive Pulmonary Disease
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Ham S, Oh YM, Roh TY
- KMID: 2447792
- Genomics Inform.
- 2019 Mar;17(1):e2.
- doi: 10.5808/GI.2019.17.1.e2
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease, featured by airflow obstruction. Recently, a comprehensive analysis of the transcriptome in lung tissue of COPD patients was... -
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- Association of mitochondrial haplogroup F with physical performance in korean population
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Hwang IW, Kim K, Choi EJ, Jin HJ
- KMID: 2447801
- Genomics Inform.
- 2019 Mar;17(1):e11.
- doi: 10.5808/GI.2019.17.1.e11
Athletic performance is a complex multifactorial trait involving genetic and environmental factors. The heritability of an athlete status was reported to be about 70% in a twin study, and at... -
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- Blood transcriptome resources of chinstrap (Pygoscelis antarcticus) and gentoo (Pygoscelis papua) penguins from the South Shetland Islands, Antarctica
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Kim BM, Jeong J, Jo E, Ahn DH, Kim JH, Rhee JS, Park H
- KMID: 2447795
- Genomics Inform.
- 2019 Mar;17(1):e5.
- doi: 10.5808/GI.2019.17.1.e5
The chinstrap (Pygoscelis antarcticus) and gentoo (P. papua) penguins are distributed throughout Antarctica and the sub-Antarctic islands. In this study, high-quality de novo assemblies of blood transcriptomes from these penguins... -
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- Advances in Serological Diagnosis of Taenia solium Neurocysticercosis in Korea
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Ahn CS, Kim JG, Huh S, Kang I, Kong Y
- KMID: 2447797
- Genomics Inform.
- 2019 Mar;17(1):e7.
- doi: 10.5808/GI.2019.17.1.e7
Cysticercosis, a parasitic disease caused by Taenia solium metacestode (TsM), has a major global public health impact in terms of disability-adjusted life years. The parasite preferentially infects subcutaneous tissue, but... -
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