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An RNA Mapping Strategy to Identify Ribozyme-Accessible Sites on the Catalytic Subunit of Mouse Telomerase

Song MS, Lee SW

  • KMID: 2166253
  • Genomics Inform.
  • 2007 Mar;5(1):32-35.
Telomerase reverse transcriptase (TERT) is an enzymatic ribonucleoprotein that prolongs the replicative life span of cells by maintaining protective structures at the ends of eukaryotic chromosomes. Telomerase activity is highly...
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ChroView: A Trace Viewer for Browsing and Editing Chromatogram files

Tae HS, Kong EB, Park KJ

  • KMID: 2166252
  • Genomics Inform.
  • 2007 Mar;5(1):30-31.
Many visualization tools have been designed to aid information processing during whole genome projects. We have developed a trace viewer program, ChroView, which can read a chromatogram file and display...
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Evaluation of Advanced Structure-Based Virtual Screening Methods for Computer-Aided Drug Discovery

Lee HS, Choi JW, Yoon SJ

  • KMID: 2166251
  • Genomics Inform.
  • 2007 Mar;5(1):24-29.
Computational virtual screening has become an essential platform of drug discovery for the efficient identification of active candidates. Moleculardocking, a key technology of receptor-centric virtual screening, is commonly used to...
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Regression Models for Haplotype-Based Association Studies

Oh SH, Namkung JH, Park TS

  • KMID: 2166250
  • Genomics Inform.
  • 2007 Mar;5(1):19-23.
In this paper, we provide an overview of statistical models for haplotype-based association studies, and summarize their features based on the design matrix. We classify the design matrix into the...
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FCAnalyzer: A Functional Clustering Analysis Tool for Predicted Transcription Regulatory Elements and Gene Ontology Terms

Kim SB, Ryu GM, Kim YJ, Heo JY, Park C, Oh BS, Kim HL, Kimm KC, Kim KW, Kim YY

  • KMID: 2166249
  • Genomics Inform.
  • 2007 Mar;5(1):10-18.
Numerous studies have reported that genes with similar expression patterns are co-regulated. From gene expression data, we have assumed that genes having similar expression pattern would share similar transcription factor...
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Construction of an RNase P Ribozyme Library System for Functional Genomics Applications

Hong SW, Choi HJ, Lee YH, Lee DK

  • KMID: 2166248
  • Genomics Inform.
  • 2007 Mar;5(1):6-9.
An RNase P ribozyme library has been developed as a tool for functional genomics studies. Each clone of this library contains a random 18-mer and the sequence of M1 RNA,...
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Detection of Neural Fates from Random Differentiation: Application of Support Vector MachineMin

Lee MS, Ahn JH, Park WY

  • KMID: 2166247
  • Genomics Inform.
  • 2007 Mar;5(1):1-5.
Embryonic stem cells can be differentiated into various types of cells, requiring a tight regulation of transcription. Biomarkers related to each lineage of cells are used to guide the differentiation...
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