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HapAnalyzer: Minimum Haplotype Analysis System for Association Studies

Jung HY, Park JS, Park YJ, Kim YJ, Kimm K, Koh IS

  • KMID: 2166173
  • Genomics Inform.
  • 2004 Jun;2(2):107-109.
SUMMARY: HapAnalyzer is an analysis system that provides minimum analysis methods for the SNP-based association studies. It consists of Hardy-Weinberg equilibrium (HWE) test, linkage disequilibrium (LD) computation, haplotype reconstruction,...
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PubMiner: Machine Learning-based Text Mining for Biomedical Information Analysis

Eom JH, Zhang BT

  • KMID: 2166172
  • Genomics Inform.
  • 2004 Jun;2(2):99-106.
In this paper we introduce PubMiner, an intelligent machine learning based text mining system for mining biological information from the literature. PubMiner employs natural language processing techniques and machine learning...
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An Iterative Normalization Algorithm for cDNA Microarray Medical Data Analysis

Kim Y, Park WY, Kim H

  • KMID: 2166171
  • Genomics Inform.
  • 2004 Jun;2(2):92-98.
No Abstract available.
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High Correlation between Alu Elements and the Conversion of 3' UTR of mRNAs Processed Pseudogenes

An HJ, Na D, Lee D, Lee KH, Bhak J

  • KMID: 2166170
  • Genomics Inform.
  • 2004 Jun;2(2):86-91.
Even though it represents 6 13% of human genomic DNA, Alu sequences are rarely found in coding regions. When in exon region, over 80 % of them are found in...
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No Evidence of Association of Interleukin 1A(-889) Genetic Polymorphism with Alzheimer's Disease in Koreans

Jhoo JH, Park WY, Kim KW, Lee KH, Lee DY, Youn JC, Suh YJ, Seo JS, Woo JI

  • KMID: 2166169
  • Genomics Inform.
  • 2004 Jun;2(2):81-85.
To examine whether the IL-1A(-889) polymorphism associates with a risk for Alzheimer's disease(AD) and acts interactively with the apolipoprotein(APOE) epsilon 4 in the development of AD, we performed genotype analyses...
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Identification of the Marker-Genes for Dioxin(2,3,7,8-tetradibenzo-p-dioxin)-Induced Immune Dysfunction by Using the High-Density Oligonucleotide Microarray

Kim JA, Lee EJ, Kim HL

  • KMID: 2166168
  • Genomics Inform.
  • 2004 Jun;2(2):75-80.
In a variety of animal species, the perinatal exposure of experimental animals to the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) leads to the immune dysfunction, which is more severe and persistent than that caused...
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Changes of Gene Expression in NIH3T3 Cells Exposed to Osmotic and Oxidative Stresses

Lee JS, Jung JH, Kim TH, Seo JS

  • KMID: 2166167
  • Genomics Inform.
  • 2004 Jun;2(2):67-74.
Cells consistently face stressful conditions, which cause them to modulate a variety of intracellular processes and adapt to these environmental changes via regulation of gene expression. Hyperosmotic and oxidative stresses...
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ChimerDB - Database of Chimeric Sequences in the GenBank

Kim N, Shin S, Cho KH, Lee S

  • KMID: 2166166
  • Genomics Inform.
  • 2004 Jun;2(2):61-66.
Fusion proteins resulting from chimeric sequences are excellent targets for therapeutic drug development. We developed a database of chimeric sequences by examining the genomic alignment of mRNA and EST sequences...
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