- Human Genome Project
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Kwon OJ
- KMID: 2202799
- J Korean Soc Biol Psychiatry.
- 2001 Nov;8(2):196-202.
The completion of the rough draft of the human genome is a remarkable achievement. It provides the overall structures of huge DNA molecules that constitute the genome and an outline... -
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- A Short History of the Genome-Wide Association Study: Where We Were and Where We Are Going
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Ikegawa S
- KMID: 2053300
- Genomics Inform.
- 2012 Dec;10(4):220-225.
- doi: 10.5808/GI.2012.10.4.220
Recent rapid advances in genetic research are ushering us into the genome sequence era, where an individual's genome information is utilized for clinical practice. The most spectacular results of the... -
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- Human Genome Project
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Kim MH
- KMID: 1536543
- J Korean Med Assoc.
- 1997 Dec;40(12):1680-1686.
No abstract available. -
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- Historical Meaning of 「Universal Declaration on the Human Genome and Human Rightã€
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Hwang SI
- KMID: 2349235
- J Korean Med Assoc.
- 1998 Mar;41(3):238-239.
- doi: 10.5124/jkma.1998.41.3.238
No abstract available. -
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- National human genome projects: an update and an agenda
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An JY
- KMID: 2406649
- Epidemiol Health.
- 2017;39:e2017045.
- doi: 10.4178/epih.e2017045
Population genetic and human genetic studies are being accelerated with genome technology and data sharing. Accordingly, in the past 10 years, several countries have initiated genetic research using genome technology... -
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- ENCODE: A Sourcebook of Epigenomes and Chromatin Language
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Yavartanoo M, Choi JK
- KMID: 1806264
- Genomics Inform.
- 2013 Mar;11(1):2-6.
- doi: 10.5808/GI.2013.11.1.2
Until recently, since the Human Genome Project, the general view has been that the majority of the human genome is composed of junk DNA and has little or no selective... -
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- Introduction of Bioinformatic Methods for the Gene Function Analysis
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Kim SS
- KMID: 760527
- Korean J Hepatol.
- 2004 Mar;10(1):11-21.
No abstract available. -
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- PrimateDB: Development of Primate Genome DB and Web Service
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Woo T, Shin G, Kang T, Kim B, Seo J, Kim SS, Kim CB
- KMID: 1572638
- Genomics Inform.
- 2005 Jun;3(2):73-76.
The comparative analysis of the human and primate genomes including the chimpanzee can reveal unique types of information impossible to obtain from comparing the human genome with the genomes of... -
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- Next Generation DNA Sequencing and Its Application in Clinical Medicine
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Cho S
- KMID: 2280986
- Korean J Perinatol.
- 2014 Sep;25(3):133-139.
- doi: 10.14734/kjp.2014.25.3.133
Watson and Crick published a paper on the double helical structure of DNA in Nature in April 25, 1953. The human genome is contained in the 23 pairs of chromosomes... -
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- Non-Synteny Regions in the Human Genome
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Lee K, Kim S
- KMID: 2166483
- Genomics Inform.
- 2010 Jun;8(2):86-89.
Closely related species share large genomic segments called syntenic regions, where the genomic elements such as genes are arranged co-linearly among the species. While synteny is an important criteria in... -
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- The Impact of Transposable Elements in Genome Evolution and Genetic Instability and Their Implications in Various Diseases
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Ayarpadikannan S, Kim HS
- KMID: 2009096
- Genomics Inform.
- 2014 Sep;12(3):98-104.
- doi: 10.5808/GI.2014.12.3.98
Approximately 45% of the human genome is comprised of transposable elements (TEs). Results from the Human Genome Project have emphasized the biological importance of TEs. Many studies have revealed that... -
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- Perspectives of International Human Epigenome Consortium
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Bae JB
- KMID: 1806265
- Genomics Inform.
- 2013 Mar;11(1):7-14.
- doi: 10.5808/GI.2013.11.1.7
As the International Human Epigenome Consortium (IHEC) launched officially at the 2010 Washington meeting, a giant step toward the conquest of unexplored regions of the human genome has begun. IHEC... -
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- Detection of hydin Gene Duplication in Personal Genome Sequence Data
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Kim JI, Ju YS, Kim S, Hong D, Seo JS
- KMID: 1469575
- Genomics Inform.
- 2009 Sep;7(3):159-162.
Human personal genome sequencing can be done with high efficiency by aligning a huge number of short reads derived from various next generation sequencing (NGS) technologies to the reference genome... -
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- Study of Modern Human Evolution via Comparative Analysis with the Neanderthal Genome
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Ahmed M, Liang P
- KMID: 2166507
- Genomics Inform.
- 2013 Dec;11(4):230-238.
- doi: 10.5808/GI.2013.11.4.230
Many other human species appeared in evolution in the last 6 million years that have not been able to survive to modern times and are broadly known as archaic humans,... -
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- Concepts of Genomic Variant Research
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Kim SY, Kim TH
- KMID: 1455839
- J Korean Orthop Res Soc.
- 2010 Jun;13(1):7-15.
Genetic variation occurs on many different scales, ranging from gross alteration in human chromosomes to single nucleotide changes. Approximately 99.5% of the human genome sequence is identical among humans. The... -
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- Trends in Next-Generation Sequencing and a New Era for Whole Genome Sequencing
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Park ST, Kim J
- KMID: 2362500
- Int Neurourol J.
- 2016 Nov;20(Suppl 2):S76-S83.
- doi: 10.5213/inj.1632742.371
This article is a mini-review that provides a general overview for next-generation sequencing (NGS) and introduces one of the most popular NGS applications, whole genome sequencing (WGS), developed from the... -
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- Post-GWAS Strategies
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Kim S, Bhak J
- KMID: 1450879
- Genomics Inform.
- 2011 Mar;9(1):1-4.
Genome-wide association (GWA) studies are the method of choice for discovering loci associated with common diseases. More than a thousand GWA studies have reported successful identification of statistically significant association... -
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- Genome Architecture and Its Roles in Human Copy Number Variation
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Chen L, Zhou W, Zhang L, Zhang F
- KMID: 2391488
- Genomics Inform.
- 2014 Dec;12(4):136-144.
- doi: 10.5808/GI.2014.12.4.136
Besides single-nucleotide variants in the human genome, large-scale genomic variants, such as copy number variations (CNVs), are being increasingly discovered as a genetic source of human diversity and the pathogenic... -
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- Exome Sequencing in Mendelian Disorders
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Lee JK
- KMID: 2184476
- J Genet Med.
- 2010 Dec;7(2):119-124.
More than 7,000 rare Mendelian diseases have been reported, but less than half of all rare monogenic disorders has been discovered. In addition, the majority of mutations that are known... -
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- Copy Number Variations in the Human Genome: Potential Source for Individual Diversity and Disease Association Studies
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Kim TM, Yim SH, Chung YJ
- KMID: 2166314
- Genomics Inform.
- 2008 Mar;6(1):1-7.
The widespread presence of large-scale genomic variations, termed copy number variation (CNVs), has been recently recognized in phenotypically normal individuals. Judging by the growing number of reports on CNVs, it... -
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