- Eosinophil Inflammation of Nasal Polyp Tissue: Relationships with Matrix Metalloproteinases, Tissue Inhibitor of Metalloproteinase-1, and Transforming Growth Factor-beta1
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Park HS, Kim SS, Kim HA, Suh YJ, Lee SK, Nahm DH, Lee YM
- KMID: 1099801
- J Korean Med Sci.
- 2003 Feb;18(1):97-102.
- doi: 10.3346/jkms.2003.18.1.97
Eosinophil and mast cell infiltrations are consistent findings in nasal polyp tissue. Previous studies have shown that matrix metalloproteinases (MMPs) may be involved in eosinophil infiltration in airway mucosa of... -
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- Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression
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Hur JH, Park MJ, Park IC, Yi DH, Rhee CH, Hong SI, Lee SH
- KMID: 1128630
- J Korean Med Sci.
- 2000 Jun;15(3):309-314.
- doi: 10.3346/jkms.2000.15.3.309
To evaluate possible roles of matrix metalloproteinase (MMP)-1, -2, tissue inhibitor of metalloproteinase (TIMP)-1, -2 and membrane-type-1 matrix metalloproteinase (MT1-MMP) in invasion of human gliomas, expressions of these proteins were... -
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- Correlation between expression of matrix metalloproteinase-2 (MMP-2), and matrix metalloproteinase-9 (MMP-9) and angiogenesis in colorectal adenocarcinoma
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Kim TS, Kim YB
- KMID: 646304
- J Korean Med Sci.
- 1999 Jun;14(3):263-270.
- doi: 10.3346/jkms.1999.14.3.263
Matrix metalloproteinases-2 (MMP-2) and matrix metalloproteinase-9 (MMP-9), which degrade extracellular matrix, are believed to play a crucial role in tumor invasion and metastasis. Angiogenesis is also perceived as an important... -
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- Reduced expression of tissue inhibitor of metalloproteinase in nodal metastasis of stomach cancer
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Ko BK, Cho HR, Choi DW, Nam CW, Park CJ, Kim GY, Kim SS, Woo YJ, Huh J, Kim MY
- KMID: 1745551
- J Korean Med Sci.
- 1998 Jun;13(3):286-290.
- doi: 10.3346/jkms.1998.13.3.286
The matrix metalloproteinases (MMPs) have been associated with tumor cell invasion and metastasis of human cancers by mediating the degradation of extracellular matrix components. Therefore, these enzymes and their... -
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- Role of tissue inhibitors of metalloproteinases (TIMPs) in colorectal carcinoma
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Joo YE, Seo KS, Kim J, Kim HS, Rew JS, Park CS, Kim SJ
- KMID: 1731316
- J Korean Med Sci.
- 1999 Aug;14(4):417-423.
- doi: 10.3346/jkms.1999.14.4.417
Increased production of matrix metalloproteinases (MMPs) has been associated with increases in invasive and metastatic potential in many types of human carcinoma. Tissue inhibitors of metalloproteinase (TIMP)-1 inhibits most interstitial... -
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- Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes
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Choi YA, Lee DJ, Lim HK, Jeong JH, Sonn JK, Kang SS, Baek SH
- KMID: 1097104
- Exp Mol Med.
- 2004 Jun;36(3):226-232.
IL-1beta is known promote cyclooxygenase-2 (COX- 2) and matrix metalloproteinase-2 (MMP-2) expression. This study focuses on the characterization of the signaling cascade associated with IL-1beta-induced matrix metalloproteinase-2 (MMP- 2) regulation... -
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- Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells
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Hong IK, Kim YM, Jeoung DI, Kim KC, Lee H
- KMID: 1056236
- Exp Mol Med.
- 2005 Jun;37(3):230-239.
Expression of matrix metalloproteinase-2 and -9 (MMP-2 and MMP-9), which correlates with tumor invasion and metastasis, has been known to be regulated by several intracellular signaling pathways. Since the CD9... -
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- Effect of IOP elevation on matrix metalloproteinase-2 in rabbit anterior chamber
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Kim CY, Kim SS, Koh HJ, You YS, Seong GJ, Hong YJ
- KMID: 754269
- Korean J Ophthalmol.
- 2000 Jun;14(1):27-31.
- doi: 10.3341/kjo.2000.14.1.27
To investigate changes in the level of matrix metalloproteinase-2 (MMP-2) in the anterior chamber of rabbit with intraocular pressure (IOP) elevation. The IOP was elevated with scleral encircling in 12... -
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- HCV core protein promotes liver fibrogenesis via up-regulation of CTGF with TGF-beta1
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Shin JY, Hur W, Wang JS, Jang JW, Kim CW, Bae SH, Jang SK, Yang SH, Sung YC, Kwon OJ, Yoon SK
- KMID: 755753
- Exp Mol Med.
- 2005 Apr;37(2):138-145.
Liver cirrhosis is one of the major complications of hepatitis C virus (HCV) infection, but the mechanisms underlying HCV-related fibrogenesis are still not clear. Although the roles of HCV core... -
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