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Spatial and Temporal Expression, and Statin Responsiveness of Galectin-1 and Galectin-3 in Murine Atherosclerosis

Lee YJ, Koh YS, Park HE, Lee HJ, Hwang BH, Kang MK, Lee SY, Kim PJ, Ihm SH, Seung KB, Chang K

BACKGROUND AND OBJECTIVES: Existing data on the spatiotemporal expression patterns of a variety of galectins in murine atherosclerosis are limited. We investigated the expression levels of galectins, and their in...
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Galectin-1, -3, -7 Expressions in Congenital and Acquired Pediatric Cholesteatomas Compared to External Auditory Canal Skin

Vander Ghinst M, Remmelink , Mansbach A, Hassid S, Choufani G

OBJECTIVES: There is a classical distinction based on clinical criteria between acquired and congenital cholesteatomas. To determine if these two types of lesions show different immunohistochemical features, we have studied...
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Clinical Implication of Galectin-1 Expression in Human Breast Cancer

Moon HG, Park JI, Lee JS, Jeong CY, Joo YT, Jung EJ, Lee YJ, Hong SC, Choi SK, Ha WS, Park ST

PURPOSE: The role of different galectins in the pathogenesis of different types of malignancy is now being intensely investigated. In this study, authors investigated the level of galectin-1 expression in...
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The Expression of Galectin-1 in Melanocytic Nevus, Dysplastic Nevus and Malignant Melanoma

Kim SM, Yoon TJ

  • KMID: 2247760
  • Korean J Dermatol.
  • 2009 Sep;47(9):989-996.
BACKGROUND: Galectin-1 (Gal-1) is a member of the galectin family of proteins, which are carbohydrate-binding proteins with an affinity for beta-galactosides. Gal-1 is differentially expressed by various normal and pathological...
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High Expression of Galectin-1, VEGF and Increased Microvessel Density Are Associated with MELF Pattern in Stage I-III Endometrioid Endometrial Adenocarcinoma

Zinovkin D, Achinovich SL, Zubritskiy MG, Whatmore J, Pranjol MZ

BACKGROUND: In this study, we investigate the expression of markers of angiogenesis and microvessel density (MVD) in cases of microcystic, elongated and fragmented (MELF) pattern, with its prognostic role in...
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Overexpression of alpha-protease Inhibitor and Galectin-1 in Radiation-induced Early Phase of Pulmonary Fibrosis

Im HS, Kim HD, Song JY, Han Y, Lee DY, Kim CW, Yun YS

  • KMID: 2270821
  • Cancer Res Treat.
  • 2006 Apr;38(2):92-98.
PURPOSE: Radiation-induced pulmonary fibrosis (RIF) is a significant complication of radiotherapy for lung cancer. Despite the large number of studies, the molecular mechanisms of RIF are poorly understood. Therefore, the...
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Search for Gene Expression in Cervical Squamous Cell Carcinoma using GeneFishing(TM) DEG PCR Technique

Yu HJ, Kim BH, Bae SM, Kim YW, Lee JM, Namkoong S, Chun HJ, Nam KH, Cho YL, Kim CK, Han BD, Ahn WS

  • KMID: 2128060
  • Korean J Obstet Gynecol.
  • 2005 Mar;48(3):617-627.
OBJECTIVE: The aim of this study was to investigate the gene expression profiles using GeneFishing(TM) DEG kit in Korean women with cervical squamous cell carcinoma. METHODS: Cervical cancer biopsies were...
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The Expression of Immunomodulation-Related Cytokines and Genes of Adipose- and Bone Marrow-Derived Human Mesenchymal Stromal Cells from Early to Late Passages

Mun CH, Kang MI, Shin YD, Kim Y, Park YB

BACKGROUND: Mesenchymal stromal cells (MSCs) are multipotent stem cells that can differentiate into several cell types. In addition, many studies have shown that MSCs modulate the immune response. However, little...
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Characteristic Changes in Decidual Gene Expression Signature in Spontaneous Term Parturition

El-Azzamy , Balogh A, Romero R, Xu Y, LaJeunesse C, Plazyo O, Xu Z, Price TG, Dong Z, Tarca AL, Papp Z, Hassan SS, Chaiworapongsa T, Kim CJ, Gomez-Lopez N, Than NG

BACKGROUND: The decidua has been implicated in the “terminal pathway” of human term parturition, which is characterized by the activation of pro-inflammatory pathways in gestational tissues. However, the transcriptomic changes...
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