- Pharmacology of Intracisternal or Intrathecal Glycine, Muscimol, and Baclofen in Strychnine-induced Thermal Hyperalgesia of Mice
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Lee IO, Son JK, Lim ES, Kim YS
- KMID: 1785997
- J Korean Med Sci.
- 2011 Oct;26(10):1371-1377.
- doi: 10.3346/jkms.2011.26.10.1371
Glycine and gamma-aminobutyric acid (GABA) are localized and released by the same interneurons in the spinal cord. Although the effects of glycine and GABA on analgesia are well known, little... -
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- Are Spinal GABAergic Elements Related to the Manifestation of Neuropathic Pain in Rat?
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Lee J, Back SK, Lim EJ, Cho GC, Kim MA, Kim HJ, Lee MH, Na HS
- KMID: 1457670
- Korean J Physiol Pharmacol.
- 2010 Apr;14(2):59-69.
- doi: 10.4196/kjpp.2010.14.2.59
Impairment in spinal inhibition caused by quantitative alteration of GABAergic elements following peripheral nerve injury has been postulated to mediate neuropathic pain. In the present study, we tested whether neuropathic... -
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- The Effect of Androsterone as the Metabolite of Testosterone to Seizure Suppression
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Kim WJ, Lee SY, Cho KJ, Lee BI
- KMID: 2185030
- J Korean Neurol Assoc.
- 2009 May;27(2):142-146.
BACKGROUND: Androsterone is one of the major metabolites from testosterone whose clinical importance remains unclear. This study evaluated the effects of androsterone on seizure susceptibility in mouse models of epilepsy. METHODS:... -
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- GABAB Receptor Modulation on the Antinociception of Intrathecal Sildenafil in the Rat Formalin Test
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Kim WM, Yoon MH, Lee HG, Han YG, Kim YO, Huang LJ, Cui JH
- KMID: 2278049
- Korean J Pain.
- 2007 Dec;20(2):106-110.
- doi: 10.3344/kjp.2007.20.2.106
BACKGROUND: A phosphodiesterase 5 inhibitor, sildenafil, has been effective against nociception. Several lines of evidence have demonstrated the role of the GABAergic pathway in the modulation of nociception. The impact... -
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- High K-induced Epileptiform Activity under GABA Antagonist and Carbamazepine in the Rat Visual Cortex
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Choi BJ
- KMID: 2329335
- J Korean Child Neurol Soc.
- 2006 May;14(1):16-23.
PURPOSE: The goal of this study was to investigate the effect of increase of K on the excitability of the visual cortex under GABA antagonist, carbamazepine(CBZP), 6-cyano-7-nitroquinoxaline-dione disodium(CNQX) and D-(-)-2-amino-5-phosphonopentanoic... -
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- Tetraethylammonium-induced Epileptiform Activity and its Modification by GABAA Antagonist in the Rat Visual Cortex
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Choi BJ
- KMID: 2329312
- J Korean Child Neurol Soc.
- 2005 Nov;13(2):137-143.
PURPOSE: The goal of this study was to investigate the effect of tetraethylammonium (TEA) on the excitability of visual cortex, and observe the induction of epileptiform activity. Also, it was... -
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- Interhemispheric Modulation on Afferent Sensory Transmission to the Ventral Posterior Medial Thalamus by Contralateral Primary Somatosensory Cortex
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Jung SC, Choi IS, Cho JH, Kim JH, Bae YC, Lee MG, Shin HC, Choi BJ
- KMID: 2285296
- Korean J Physiol Pharmacol.
- 2004 Jun;8(3):129-132.
Single unit responses of the ventral posterior medial (VPM) thalamic neurons to stimulation were monitored in anesthetized rats during activation of contralateral primary somatosensory (SI) cortex by GABA antagonist. The... -
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- Spinal Gabapentin and Antinociception: Mechanisms of Action
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Yoon MH, Choi JI, Jeong SW
- KMID: 2157631
- J Korean Med Sci.
- 2003 Apr;18(2):255-261.
- doi: 10.3346/jkms.2003.18.2.255
Spinal gabapentin has been known to show the antinociceptive effect. Although several assumptions have been suggested, mechanisms of action of gabapentin have not been clearly established. The present study was... -
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- Effects of GABA on pancreatic exocrine secretion of rats
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Park HS, Park HJ
- KMID: 1026939
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S24-S26.
- doi: 10.3346/jkms.2000.15.S.S24
Since GABA and its related enzymes had been determined in beta-cells of pancreas islets, effects of GABA on pancreatic exocrine secretion were investigated in the isolated perfused rat pancreas. GABA, given intra-arterially... -
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- Influence of Glutamate on the Circling Movement In the Unilateral Substantia Nigra-lesioned Rats
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Han MI, Chung YC, Eun HB
- KMID: 2340101
- J Korean Neuropsychiatr Assoc.
- 1997 Sep;36(5):919-926.
The aim of this study was to examine the effects of various concentrations of glutamate(10(-8), 10(-6) and 10(-4) M) on the circling movement induced by apomorphine in the unilateral substantia... -
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