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Three ongoing intraperitoneal chemotherapy trials in ovarian cancer

Fujiwara K

No abstract available.
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A Refined Coronary Computed Tomography Procedure Reveals an Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery, Including the Collateral Artery

Nagayoshi S, Nakajima T, Tonegawa R, Fujii S, Murakami A, Suzuki T, Fujiwara K, Miyamoto T, Muto M

Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA), which has also been termed Bland-White-Garland syndrome, is a rare congenital anomaly of the coronary artery that accounts...
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Olaparib plus bevacizumab as maintenance therapy in patients with newly diagnosed, advanced ovarian cancer: Japan subset from the PAOLA-1/ENGOT-ov25 trial

Fujiwara K, Fujiwara H, Yoshida H, Satoh T, Yonemori K, Nagao S, Matsumoto T, Kobayashi H, Bourgeois H, Harter P, Mosconi AM, Vazquez IP, Reinthaller A, Fujita T, Rowe P, Pujade-Lauraine E, Ray-Coquard I

Objective The addition of maintenance olaparib to bevacizumab demonstrated a significant progression-free survival (PFS) benefit in patients with newly diagnosed, advanced ovarian cancer in the PAOLA-1/ENGOT-ov25 trial (NCT02477644). We evaluated maintenance...
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Pazopanib as a second line treatment for uterine and ovarian carcinosarcoma: a single institutional study

Nishikawa , Hasegawa K, Yabuno A, Yoshida H, Yasuda M, Kozawa E, Fujiwara K

No abstract available.
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Evaluation of Circulating Tumor DNA in Patients with Ovarian Cancer Harboring Somatic PIK3CA or KRAS Mutations

Ogasawara A, Hihara T, Shintani D, Yabuno A, Ikeda Y, Tai K, Fujiwara K, Watanabe K, Hasegawa K

Purpose Circulating tumor DNA (ctDNA) is an attractive source for liquid biopsy to understand molecular phenotypes of a tumor non-invasively, which is also expected to be both a diagnostic and prognostic...
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Various types of total laparoscopic nerve-sparing radical hysterectomies and their effects on bladder function

Kanao H, Fujiwara K, Ebisawa K, Hada T, Ota Y, Andou M

OBJECTIVE: This study was conducted to ascertain the correlation between preserved pelvic nerve networks and bladder function after laparoscopic nerve-sparing radical hysterectomy. METHODS: Between 2009 and 2011, 53 patients underwent total...
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Domains of the Kihon Checklist Associated with Prefrailty among Community-Dwelling Older Adults

Kamasaki T, Otao H, Hachiya M, Kubo A, Okawa H, Fujiwara K, Sakamoto A, Shimokihara S, Maruta M, Han G, Tabira T

Background: Various functions are involved in prefrailty. However, no studies have examined more relevant functions. Therefore, this study examined the domains of the Kihon Checklist (KCL) associated with prefrailty by...
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Calcar Femorale in Patients with Osteoarthritis of the Hip Secondary to Developmental Dysplasia

Tetsunaga , Fujiwara K, Endo H, Tetsunaga , Shiota N, Sato T, Ozaki T

BACKGROUND: We investigated whether the calcar femorale, a cortical septum in the region of the lesser trochanter of the femur, correlates with results of femoral stem implantation in patients with...
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High expression of maternal embryonic leucine-zipper kinase (MELK) impacts clinical outcomes in patients with ovarian cancer and its inhibition suppresses ovarian cancer cells growth ex vivo

Ikeda Y, Sato S, Yabuno A, Shintani D, Ogasawara A, Miwa M, Zewde M, Miyamoto T, Fujiwara K, Nakamura Y, Hasegawa K

Objective: Maternal embryonic leucine zipper kinase (MELK) is receiving an attention as a therapeutic target in various types of cancers. In this study, we aimed to evaluate the prognostic significance...
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The post-progression survival of patients with recurrent or persistent ovarian clear cell carcinoma: results from a randomized phase III study in JGOG3017/GCIG

Kondo E, Tabata T, Suzuki N, Aoki D, Yahata H, Kotera Y, Tokuyama O, Fujiwara K, Kimura E, Terauchi F, Sumi T, Okamoto A, Yaegashi N, Enomoto T, Sugiyama T

Objective: In this study we sought to investigate the clinical factors that affect postprogression survival (PPS) in patients with recurrent or persistent clear cell carcinoma (CCC). We utilized the JGOG3017/Gynecological Cancer...
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