- Temporal Variant of Frontotemporal Dementia: A Case of Semantic Dementia
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Kim DS, Kim YD, Ryu SH, Kim YD, Choi YC
- KMID: 1582550
- J Korean Neurol Assoc.
- 2002 Jan;20(1):82-85.
Semantic dementia is a rare, distinct form of frontotemporal lobar degeneration, characterized by a deficit in semantic memory with relative preservation of attention and executive functions. We report a case... -
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- Frontotemporal Lobar Degeneration
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Shin IS
- KMID: 2334056
- J Korean Geriatr Psychiatry.
- 2007 Dec;11(2):55-61.
Frontotemporal lobar degeneration (FTLD) is a progressive dementia with prominent neuropsychiatric features, aphasia or both. FTLD predominantly affects the frontal and anterior part of temporal cortex. FTLD is classified into... -
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- Clinical and Pathological Characteristics of Frontotemporal Lobar Degeneration(FTLD) and Molecular Genetics of Tau Protein
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Woo SI
- KMID: 2202778
- J Korean Soc Biol Psychiatry.
- 2003 Nov;10(2):97-106.
Criticisms about amyloid cascade hypothesis of Alzheimer's disease(AD) are based on the findings, first, that the degree of dementia does not correlate with the number of plaques, and second, that... -
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- A Case of Idiopathic Parkinson's Disease Combined with Progressive Nonfluent Aphasia
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Kim EJ, Suh MK, Park KC, Jeong Y, Chin J, Lee WY, Na DL
- KMID: 1585779
- J Korean Neurol Assoc.
- 2004 Apr;22(2):152-156.
It is not uncommon for idiopathic parkinson's disease (IPD) to occur concurrently with other degenerative dementing disorders such as Alzheimer's disease. However, there has been no report about the comorbidity... -
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- The Pathogenetic Role of TAR DNA Binding Protein (TDP-43) in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
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Kang SY
- KMID: 2065761
- J Korean Neurol Assoc.
- 2011 Feb;29(1):1-8.
The recent identification of the transactive response DNA binding protein with a molecular weight of 43 kDa (TDP-43) as the major pathological protein, in both amyotrophic lateral sclerosis (ALS) and... -
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- An Autopsy Confirmed Case of Semantic Variant Primary Progressive Aphasia with Frontotemporal Lobar Degeneration-TDP type C
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Jung NY, Lee MJ, Lee JH, Shin JH, Lee YM, Shin MJ, Pak K, Hwang C, Ahn JW, Sung S, Choi KU, Huh GY, Kim EJ
- KMID: 2435783
- J Korean Neurol Assoc.
- 2018 Feb;36(1):35-39.
- doi: 10.17340/jkna.2018.1.8
A 62-year-old man presented with a one-year history of word finding difficulty, impaired single word comprehension and personality changes including aggression, apathy and eating change. Brain MRIs showed severe atrophy... -
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- An Autopsy Case of Frontotemporal Dementia with Motor Neuron Disease
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Kim EJ, Oh EH, Kim KT, Jung Y, Lee JH, Lee JH, Lee YM, Kim SJ, Shin JH, Shin MJ, Lee MJ, Ahn JW, Sung S, Choi KU, Jung DS, Seeley WW, Huh GY
- KMID: 2184605
- J Korean Neurol Assoc.
- 2015 Aug;33(3):201-205.
- doi: 10.17340/jkna.2015.3.12
Approximately 15% of patients with frontotemporal dementia (FTD) have co-occurring motor neuron disease (MND). FTD-MND cases have frontotemporal lobar degeneration (FTLD)-transactive response DNA-binding protein (TDP) pathology, which is divided into... -
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- Primary Progressive Aphasia and the Left Hemisphere Language Network
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Mesulam MM
- KMID: 2442833
- Dement Neurocogn Disord.
- 2016 Dec;15(4):93-102.
- doi: 10.12779/dnd.2016.15.4.93
Primary progressive aphasia (PPA) is a clinical syndrome diagnosed when three core criteria are met. First, there should be a language impairment (i.e., aphasia) that interferes with the usage or... -
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- Clinical Features and Therapeutic Approaches of Frontotemporal Dementia
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Lee KJ
- KMID: 2137453
- J Korean Geriatr Psychiatry.
- 2012 Dec;16(2):67-74.
Frontotemporal dementia (FTD), formerly called Pick's disease, is a progressive dementia that is associated with focal atrophy of the frontal and/or temporal lobes. FTD has three major clinical subtypes ;... -
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- Development of tau PET Imaging Ligands and their Utility in Preclinical and Clinical Studies
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Choi Y, Ha S, Lee YS, Kim YK, Lee DS, Kim DJ
- KMID: 2407298
- Nucl Med Mol Imaging.
- 2018 Feb;52(1):24-30.
- doi: 10.1007/s13139-017-0484-7
The pathological features of Alzheimer's disease are senile plaques which are aggregates of β-amyloid peptides and neurofibrillary tangles in the brain. Neurofibrillary tangles are aggregates of hyperphosphorylated tau proteins, and... -
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- Neuropsychological and Neuroimaging Findings of Semantic Dementia
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Kwon JC, Kang SJ, Chin JH, Kang YW, Lee YM, Kim HH, Park JM, Kim SE, Na DL
- KMID: 2186004
- J Korean Neurol Assoc.
- 2001 Nov;19(6):598-607.
BACKGROUND: Semantic dementia (SD) is a temporal variant of frontotemporal lobar degeneration (FTLD), which is characterized by naming difficulty, decreased comprehension of words, prosopagnosia and object visual agnosia. We report... -
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- Prognosis of Patients with Behavioral Variant Frontotemporal Dementia Who have Focal Versus Diffuse Frontal Atrophy
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Lee JS, Jung NY, Jang YK, Kim HJ, Seo SW, Lee J, Kim YJ, Lee JH, Kim BC, Park KW, Yoon SJ, Jeong JH, Kim SY, Kim SH, Kim EJ, Park KC, Knopman DS, Na DL
- KMID: 2391666
- J Clin Neurol.
- 2017 Jul;13(3):234-242.
- doi: 10.3988/jcn.2017.13.3.234
BACKGROUND AND PURPOSE: Only a few studies have investigated the relationship between different subtypes and disease progression or prognosis in patients with behavioral variant frontotemporal dementia (bvFTD). Since a localized... -
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