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Distribution of the Bovine Lens Antigen in the Ocular Tissues

Oh CK, Youn WS

  • KMID: 1659043
  • J Korean Ophthalmol Soc.
  • 1976 Mar;17(1):53-58.
Distribution of the antigens of soluble lens protein in the bovine ocular tissues was studied by Ouchterlony's double agar diffusion technique. Guinea pig anti-bovine-lens-serum was prepared by 4 weekly injections...
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MIF Test Using Lens Protein as Antigen

Chung H

  • KMID: 2204604
  • J Korean Ophthalmol Soc.
  • 1976 Dec;17(4):415-419.
This experiment was performed to demonstrate that the cell-mediated hypersensitivity plays an important role in the development of the so-called endophthalmitis phaooanaphylactica. Fifteen albino guinea pigs were immunized with sclubte...
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Experimental Studies on the Lens-Induced Uveitis

Youn WS

  • KMID: 1659042
  • J Korean Ophthalmol Soc.
  • 1976 Mar;17(1):47-51.
This experiment was performed in an attempt to reproduce endophthalmitis phacoanaphylactica in guinea-pigs sensitized to lens protein. Twenty-four albino guinea-pigs were immunized with soluble proteins of beef lenses with complete...
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Anti-inflammatory, Anti-arthritic and Analgesic Effect of the Herbal Extract Made from Bacopa monnieriis, Cassia fistula and Phyllanthus polyphyllus

Yoon WH, Lee KH

Anti-inflammatory, anti-arthritic and analgesic activity of each herbal extract, which is extracted from Bacopa monnieriis, Cassia fistula and Phyllanthus polyphyllus, respectively. The treatment of herbal extract exhibited anti-inflammatory effect as...
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Prophylactic effect of plaster and cataplasm contained ketoprofen in rats with adjuvant arthritis

Kang SS, Choi SH

  • KMID: 1103509
  • J Vet Sci.
  • 2001 Apr;2(1):65-70.
This study demonstrates that prophylactic effect of plaster and cataplasm contained ketoprofen in adjuvant arthritis therapy by X-ray. Adjuvant arthritis was induced by a single injection of Freund's complete adjuvant....
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Principles and Application of Mouse Model of Allergic Rhinitis

Mo JH

Allergic rhinitis is a one of the most prevalent disease and its prevalence has been increasing these days. Many researchers have used the mouse models to study the mechanism of...
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Responses of the Nociceptive Axons to the Inflammatory Mediators and Tumor Necrosis Factor-alpha

Lee JR, Park SC, Leem JG, Bove GM

BACKGROUND: Following musculoskeletal injuries, axons are exposed to tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. Exposure of axons to TNF-alpha and complete Freund's adjuvant (CFA) can cause hyperalgesia...
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Effective Production and Clinical Application of Anti-Interleukin-6 Monoclonal Antibodies

Nam KS, Choi IP, Kim CH, Choi MJ, Yang JH, Moon JO

  • KMID: 1928279
  • Korean J Immunol.
  • 1998 Sep;20(3):289-294.
Highly specific and sensitive immunoassay method for soluble human recombinant interleukin-6 (hu rlL-6) was established by two different immunization methods. One is conventional method by Freund's adjuvant method and the...
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The Effect of Homologous Epididymal Extracts on Spermatogenesis in Mouse

Kim KB, Kim KS

  • KMID: 1911736
  • Korean J Urol.
  • 1982 Dec;23(8):1171-1174.
A number of tissues have been studied in the past with respect to their organ-specific antigens. In many instances it has been possible to produce autoantibodies against characteristic components. The...
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Change in the Synthesis of Brain-Derived Neurotrophic Factor in the Dorsal Root Ganglion Following Peripheral Inflammation

Kim SY, Kim JK, Kim HS, Lee SJ, Ha SO, Hong HS, Kim DS, Cho HJ

  • KMID: 1530110
  • Korean J Anat.
  • 1998 Jun;31(3):439-446.
It is well known that nerve growth factor (NGF) may serve as a link between inflammation and hyperalgesia. However, there is little information whether brain-derived neurotrophic factor (BDNF), another family...
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Effects of Electroacupuncture on the Expression of Spinal Neuronal Nitric Oxide Synthase in Adjuvant-induced Arthritic Rat Model

Ryu JW, Gil YG, Choi BT

  • KMID: 1583641
  • Korean J Phys Anthropol.
  • 2006 Sep;19(3):215-222.
To examine the effects of electroacupuncture (EA) on central nociceptive modulation, expressional changes of spinal neuronal nitric oxide synthase (nNOS) were investigated in complete Freund's adjuvant (CFA)-injected rats. Inflammation was induced by...
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An Effect of Anti-Testicular Rabbit Serum on Rat Testis

Soh BU, Kim KS

  • KMID: 1911550
  • Korean J Urol.
  • 1983 Oct;24(5):701-705.
Evidence of the antigenicity of testis and semen was first presented at the end of the last century. Landsteiner (1899), Metchnikoff (1900), and Metalnikoff (1900) demonstrated the induction of a...
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Vitamin E Reduces Symptoms in a CFA-induced Model of Monoarthritis

Lee KC, Moon KH, Kim DK, Lee KS, Woo NS, Lee YC

BACKGROUND: Adjuvant arthritic animals show immunologic and inflammatory features which are also observed in patients with rheumatoid arthritis. This study investigated whether high dose vitamin E (alpha-tocopherol) has any additional...
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House Dust Mite Allergic Rhinitis Model in C57BL/6 Mice

Yun JB, Lee HH, Kwon TY

  • KMID: 1874316
  • Korean J Otolaryngol-Head Neck Surg.
  • 2000 Mar;43(3):276-282.
BACKGROUND AND OBJECTIVES: The animal model of allergic rhinitis is important to study the pathophysiology of allergy and to design an effective therapy to ameliorate allergic diseases. Despite of numerous...
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Transfer of Experimental Autoimmune Uveoretinitis by Serum

Youn WS, Kozak YD, Faure JP

  • KMID: 2336338
  • J Korean Ophthalmol Soc.
  • 1974 Dec;15(4):269-275.
Passive transfer experiments were performed by local administrations of sera from guinea pigs hyperimmunized by bovine rod outer segments with complete Freund's adjuvant in random-bred guinea pigs. Routes of administrations...
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Studies on the Cellular Transfer of Autoimmune Uveitis

Min BS, Youn WS

  • KMID: 1948426
  • J Korean Ophthalmol Soc.
  • 1976 Sep;17(3):259-264.
After the immunization of pigmented guinea pigs with bovine rod outer segments in complete Freund's adjuvant, the regional lymph nodes were excised, teased and sedimented by centrifugation. These fresh lymphocytes...
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Mechanism of Hyperalgesia Following Cutaneous Inflammation by Complete Freund Adjuvant

Jeong Y, Leem JW, Chung SS, Kim YS, Yoon DM, Nam TS, Paik KS

  • KMID: 2335903
  • J Korean Pain Soc.
  • 2000 Nov;13(2):164-174.
BACKGROUND: After an injury to tissue such as the skin, hyperalgesia develops. Hyperalgesia is characterized by an increase in the magnitude of pain evoked by noxious stimuli. It has been...
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A Blockade of the Central MAPK Pathway Attenuates Referred Pain in Rats with Complete Freund's Adjuvant-Induced Inflammation of the Temporomandibular Joint

Won KA, Lim NH, Lee MK, Park MK, Yang GY, Park YY, Ahn DK, Bae YC

  • KMID: 1457180
  • Int J Oral Biol.
  • 2010 Sep;35(3):83-89.
We investigated the role of the central MAPK pathways in extra-territorial (referred) pain resulting from inflammation of the temporomandibular joint (TMJ). Experiments were carried out on male Sprague-Dawley rats weighing...
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Dermatophagoides Farinae-Induced Asthmatic Mouse Model of Airway Remodeling

  • KMID: 2299724
  • Korean J Asthma Allergy Clin Immunol.
  • 2004 Sep;24(3):310-317.
BACKGROUND: Although murine models have been useful in understanding acute airway inflammation in asthma, the ovalbumin induced murine models of asthma have significant limitations in study of airway remodeling. OBJECTIVE: We...
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Antinociceptive Effects of Prim-O-Glucosylcimifugin in Inflammatory Nociception via Reducing Spinal COX-2

Wu LQ, Li Y, Li YY, Xu SH, Yang ZY, Lin Z, Li J

We measured anti-nociceptive activity of prim-o-glucosylcimifugin (POG), a molecule from Saposhnikovia divaricate (Turcz) Schischk. Anti-nociceptive or anti-inflammatory effects of POG on a formalin-induced tonic nociceptive response and a complete Freund's...
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