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Anaphylactoid reaction to ofloxacin with cross-reactivity to other fluoroquinolones

Kim CW, Kim DY, Ryu ST, Kang SY, Jang CS

  • KMID: 2285828
  • J Asthma Allergy Clin Immunol.
  • 2004 Mar;24(1):146-151.
Fluoroquinolones are antimicrobial agents that have a broad range of activity against both gram-negative and gram-positive organisms. Anaphylactoid reactions have been sporadically reported with fluoroquinolones. There have been a few...
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The Use of Fluoroquinolones in Children: Recent Advances

Choi KM

Fluoroquinolones have been widely used since the development of nalidixic acid because of the excellent spectrum of activity, superior tissue penetration, and convenient route of administration. Despite such advantages, the...
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Current Updates in Pharmacokinetics and Pharmacodynamics of Fluoroquinolones

Ko YH, Song PH

The ultimate goal of antimicrobial treatment is to decrease the morbidity and mortality related to infection. Maximizing these outcomes requires an understanding of the complex interactions between the drug administered,...
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The use of fluoroquinolone in children

Hur JK

The fluoroquinolones are an important group of antibiotics widely used in the treatment of various infectious diseases in adults, as a result of an excellent spectrum of activity, good tissue...
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Systemic use of fluoroquinolone in children

Choi SH, Kim EY, Kim YJ

Fluoroquinolones are an important class of antibiotics that are widely used in adult patients because of their broad spectrum of activity, good tissue penetration, and oral bioavailability. However, fluoroquinolone use...
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A Case of Hypersensitivity Reaction to Gemifloxacin

  • KMID: 1850203
  • Korean J Asthma Allergy Clin Immunol.
  • 2006 Jun;26(2):159-162.
Gemifloxacin, a compound of the fluoroquinolone, is a broad-spectrum oral antibacterial agent. The most common adverse effects of fluoroquinolones are gastrointestinal manifestations and incidence of cutaneous adverse effects is 0.7%....
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The Choice of Empirical Treatment of Uncomplicated Cystitis: No Longer Free Ride

Kim TH

Resistance of uropathogenic E. coli to trimethoprim/sulfamethoxazole in Korea has surpassed the threshold of 20% at which the drug is no longer recommended for empirical treatment and routine urine culture...
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Uropathogens Based on Antibiotic Susceptibility

Lee SW, Kim YH

Urinary tract infections are one of the most commonly encountered infections in clinical practice. Due to the emergence of and increase in urinary tract bacteria that are resistant to trimethoprim-sulfamethoxazole,...
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Impact of Intervention by an Antimicrobial Stewardship Team on Conversion from Intravenous to Oral Fluoroquinolones

Park SM, Kim HS, Jeong YM, Lee JH, Lee E, Lee E, Song KH, Kim HB, Kim ES

BACKGROUND: Early conversion from intravenous to oral antibiotics plays an important role in lowering the risk of catheter-associated infections, reducing the workload of nurses, decreasing direct and indirect costs, and...
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Antibiotic Resistance in Helicobacter pylori

Kim JM

  • KMID: 1523327
  • Hanyang Med Rev.
  • 2007 Aug;27(3):76-91.
Although Helicobacter pylori is susceptible to many antibiotics in vitro, only a few antibiotics, including amoxicillin, clarithromycin, metronidazole, tetracycline, and fluoroquinolones, have been frequently used in vivo to cure the...
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Antibacterial and Pharmacological Evaluation of Fluoroquinolones: A Chemoinformatics Approach

Sood D, Kumar N, Singh A, Sakharkar , Tomar V, Chandra R

Fluoroquinolone (FQ) antibiotics are an important class of synthetic antibacterial agents. These are the most extensively used drugs for treating bacterial infections in the field of both human and veterinary...
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Drugs in leprosy

Park EM

  • KMID: 1512598
  • Korean Lepr Bull.
  • 2006 Jun;39(1):49-58.
Chemotherapy is a main component of treatments for leprosy. The World Health Organization (WHO) recommends multiple-drug therapy (MDT) consisting of dapsone, clofazimine and monthly rifampin as the first-line drugs against...
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Current Status of Fluoroquinolone Use for Treatment of Tuberculosis in a Tertiary Care Hospital in Korea

Kang BH, Jo KW, Shim TS

BACKGROUND: Fluoroquinolones are considered important substitutes for the treatment of tuberculosis. This study investigates the current status of fluoroquinolone for the treatment of tuberculosis. METHODS: In 2009, a retrospective analysis was...
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Delafloxacin, a New Miracle in Antibiotics Armamentarium for Bacterial Infections

Rahman MS, Koh YS

The persistent antibiotics resistant issue has emerged as an influencing factor to deteriorate community health. So, new antibiotics development is urgent for the treatment of bacterial infections. Alternatively, delafloxacin is...
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Clinical Effects of Gemifloxacin on the Delay of Tuberculosis Treatment

Kim SY, Yim JJ, Park JS, Park SS, Heo EY, Lee CH, Chung HS, Kim DK

Although gemifloxacin has low in vitro activity against Mycobacterium tuberculosis, the effect of gemifloxacin on the delay of tuberculosis (TB) treatment has not been validated in a clinical setting. The...
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In-Vitro Activity of Tosufloxacin Compared with Levofloxacin and Ofloxacin against Uropathogens, Isolated from Acute Uncomplicated Cystitis in Female Outpatients

Lee SJ, Lee KS, Jeong SJ, Lee SE, Cho YH

  • KMID: 1528884
  • Infect Chemother.
  • 2007 Aug;39(4):202-207.
BACKGROUND: Tosufloxacin is one of the fluoroquinolones with higher antibacterial activity against many organisms than other fluoroquinolones developed previously. However, the antimicrobial susceptibilities of tosufloxacin against uropathogens are not well...
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Treatment of Drug Susceptible Pulmonary Tuberculosis

Shin HJ, Kwon YS

Tuberculosis (TB) remains a major global health problem, and the incidence of TB cases has not significantly decreased over the past decade in Korea. The standard short course regimen is...
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Chronic Bacterial Prostatitis

Park HJ

Men with prostatitis-like symptoms who had uropathogenic bacteria localized to the prostate gland by elaborate collection and culturing techniques were diagnosed with chronic bacterial prostatitis. Chronic bacterial prostatitis is characterized...
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Efficiency of Moxifloxacin in the Treatment of Helicobacter pylori Infection

Altun B, Ozturk K

No abstract available.
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A Case of Levofloxacin-Induced Anaphylaxis With Elevated Serum Tryptase Levels

Lee JH, Lee WY, Yong SJ, Shin KC, Lee MK, Kim CW, Kim SH

Levofloxacin, a fluoroquinolone and L-isomer of the racemate ofloxacin, has been approved for the treatment of acute and chronic bacterial infections. Gastrointestinal complaints are the most frequently reported adverse drug...
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