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The evaluation of cellular immune function in elderly patients with systemic lupus erythematosus

Men K, Chen Y, Zhang J, Wei D

BACKGROUND/AIMS: To evaluate cellular immune function in systemic lupus erythematosus (SLE) patients over 60 years old, the association between antinuclear antibody (ANA) titers and the ratio of CD4⁺/CD8⁺ was analyzed...
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Quantification of Immunoglobulin G against Trypanosoma cruzi in Individuals with Chronic Chagas Disease Treated with Nifurtimox and Evaluated in Prolonged Follow-Up

Muñoz G, Vergara C, Martínez , Apt W, Zulantay I

In the indeterminate chronic period of Chagas disease (ChD) the treatment has not been conclusive, because the serological negativization requires many years. This study aims to evaluate the efficacy of...
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Tissue-Clearing Technique and Cutaneous Nerve Biopsies: Quantification of the Intraepidermal Nerve-Fiber Density Using Active Clarity Technique-Pressure Related Efficient and Stable Transfer of Macromolecules Into Organs

Kim DH, Lee SJ, Lee E, Hong JH, Seo SH, Ahn HH, Kim BJ, Sun W, Rhyu IJ

BACKGROUND AND PURPOSE: Cutaneous nerve biopsies based on two-dimensional analysis have been regarded as a creditable assessment tool for diagnosing peripheral neuropathies. However, advancements in methodological imaging are required for...
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Serologic Survey and Risk Factors for Coxiella burnetii Infection among Dairy Cattle Farmers in Korea

Park JH, Chu H, Yoo SJ, Hwang KJ, Lim HS

BACKGROUND: The zoonotic disease Q fever is caused by Coxiella burnetii and usually affects high-risk human populations. We conducted a serological survey of dairy cattle farmers in Korea to determine...
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Insect Bite-Like Reaction with Bullous Lesions Mimicking Bullous Pemphigoid in a Patient with Chronic Lymphocytic Leukemia

Kim JE, Kim SC

Patients with chronic lymphocytic leukemia (CLL) rarely exhibit an exaggerated insect bite-like reaction without a history of an arthropod bite. We report a case of an insect bite-like reaction in...
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A Case of Anti-reticulin Antibody-positivity in Metachronous Double Primary Cancer

Kim KN, Jearn LH, Kim TY

No abstract available.
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Severe Scrub Typhus with Hemophagocytic Lymphohistiocytosis Occurring in Summer

Ahn JS, Noh JH, Kim HR, Jung J, Jo JC, Lim JH, Jun JB

In Korea, scrub typhus usually occurs in October and November. Hemophagocytic lymphohistiocytosis (HLH) is a distinct clinical entity characterized by a high fever, pancytopenia, hepatosplenomegaly, histiocyte proliferation, and hemophagocytosis. We...
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Increase of proliferation and DNA damage in mouse hepatocytes treated with diethylnitrosamine

Lee WK, Kang JS

As diethylnitrosamine (DEN) effect on cell proliferation, DNA damage and stem cell marker(s) expression have been largely unknown in mouse normal hepatocytes (AML-12 cells) cultured over a short-term period, this...
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Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea

Lee SH, Heo JY, Lee HK, Lee YS, Jeong HW, Hwang SD

Although Q fever is an important zoonotic infection with a worldwide distribution, no human isolates of Coxiella burnetii have been identified in Korea. For the first time, we identified the...
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Seroreactivity to Q Fever Among Slaughterhouse Workers in South Korea

Chu H, Yoo SJ, Hwang KJ, Lim HS, Lee K, Park MY

OBJECTIVES: Q fever is a zoonotic disease that occurs worldwide; however, little is known about its prevalence in South Korea. We attempted to determine the prevalence of Q fever seroreactivity...
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Performance of an Automated Fluorescence Antinuclear Antibody Image Analyzer

Yoo IY, Oh JW, Cha HS, Koh EM, Kang ES

BACKGROUND: The gold standard for antinuclear antibody (ANA) screening is the indirect immunofluorescence (IIF) assay with human epithelial cells (HEp-2). However, a number of substantial disadvantages of manual IIF assays...
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Detection of Autoantibodies against Aquaporin-1 in the Sera of Patients with Primary Sjögren's Syndrome

Alam J, Choi YS, Koh JH, Kwok SK, Park SH, Song YW, Park K, Choi Y

The pathophysiology of glandular dysfunction in Sjögren's syndrome (SS) has not been fully elucidated. Previously, we reported the presence of autoantibodies to AQP-5 in patients with SS, which was associated...
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A serological study of severe fever with thrombocytopenia syndrome using a virus neutralization test and competitive enzyme-linked immunosorbent assay

Lee H, Kim EJ, Cho IS, Song JY, Choi JS, Lee JY, Shin YK

Severe fever with thrombocytopenia syndrome (SFTS) is caused by the SFTS virus (SFTSV). The SFTSV appears to have a wide host range, as SFTSV-positive ticks have been isolated from both...
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Clinical Evaluation of Rapid Diagnostic Test Kit for Scrub Typhus with Improved Performance

Kim YJ, Park S, Premaratna R, Selvaraj S, Park SJ, Kim S, Kim D, Kim MS, Shin DH, Choi KC, Kwon SH, Seo W, Lee NT, Kim SH, Kang HK, Kim YW

Diagnosis of scrub typhus is challenging due to its more than twenty serotypes and the similar clinical symptoms with other acute febrile illnesses including leptospirosis, murine typhus and hemorrhagic fever...
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A Case of Epidermolysis Bullosa Acquisita Associated with Psoriasis

Moon KR, Yun SJ, Kim SJ, Lee SC, Won YH, Lee JB

  • KMID: 2344378
  • Korean J Dermatol.
  • 2016 Jul;54(6):464-467.
Epidermolysis bullosa acquisita (EBA) is an autoimmune subepidermal blistering disease characterized by the presence of circulating IgG autoantibodies to type VII collagen. Various types of autoimmune blistering disease have been...
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Comparison of Nasopharyngeal Aspirates and Nasopharyngeal Flocked Swabs for Respiratory Virus Detection

Sung H, Kang JO, Lee NY, Lee CK, Kim HS, Lee KM, Kim EC

BACKGROUND: Nasopharyngeal aspirate (NPA) is known as the best specimen for accurate diagnosis of viral respiratory infections in pediatric patients, but the procedure is very annoying. Recently introduced flocked swabs...
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Bullous Scabies with Bullous Pemphigoid

Kang JH, Lee JH, Kim TY

  • KMID: 1720689
  • Korean J Dermatol.
  • 2014 Aug;52(8):563-566.
We report a rare case of bullous scabies with bullous pemphigoid in a 59-year-old male patient. He presented with a 9-month history of exhibiting multiple, variable-sized, red-to-brown, pruritic cutaneous patches,...
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Isolation, in vitro propagation, genetic analysis, and immunogenic characterization of an Ehrlichia canis strain from southeastern Brazil

Alves RN, Rieck SE, Ueira-Vieira C, Labruna MB, Beletti ME

Amplification of the 16S rRNA gene from a blood sample obtained from a dog in southeastern Brazil was used to confirm a naturally acquired Ehrlichia (E.) canis infection. Following isolation...
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Anti-N-Methyl-D-Aspartate Receptor Encephalitis in Korea: Clinical Features, Treatment, and Outcome

Lim JA, Lee ST, Jung KH, Kim S, Shin JW, Moon J, Byun JI, Kim TJ, Shin YW, Lee KJ, Kim YS, Park KI, Lee SK, Chu K

BACKGROUND AND PURPOSE: Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is the most common type of autoimmune synaptic encephalitis and it often responds to treatment. We analyzed the clinical characteristics of anti-NMDAR encephalitis...
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Seroprevalence of Plasmodium vivax in the Republic of Korea (2003-2005) using Indirect Fluorescent Antibody Test

Kim TS, Kang YJ, Lee WJ, Na BK, Moon SU, Cha SH, Lee SK, Park YK, Pak JH, Cho PY, Sohn Y, Lee HW

Plasmodium vivax reemerged in the Republic of Korea (ROK) in 1993, and is likely to continue to affect public health. The purpose of this study was to measure levels of...
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