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Development of flavonoid database for commonly consumed foods by Koreans

Yang YK, Kim JY, Kwon O

Flavonoids have been hypothesized to reduce the risk of chronic diseases, but the lack of a flavonoid database hampered epidemiological studies addressing this issue in Korea. In this study, we...
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Relationship between flavonoids intake and metabolic syndrome in Korean women with polycystic ovary syndrome

Oh JS, Ahn MJ, Han CJ, Kim H, Kwon O, Chung HW, Chang N

  • KMID: 2327150
  • J Nutr Health.
  • 2014 Jun;47(3):176-185.
PURPOSE: The purpose of this study was to investigate the relationship between dietary flavonoids intake and metabolic syndrome (MetS) in Korean women with polycystic ovary syndrome (PCOS). METHODS: A total of...
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Flavonoid intake according to food security in Korean adults: Based on the Korea National Health and Nutrition Examination Survey 2007~2012

Jun S, Hong E, Joung H

PURPOSE: The aim of this study was to examine the association of food security with the total and individual flavonoid intakes among Korean adults. METHODS: Study subjects were 13,454 men and...
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Estimated dietary flavonoids intake of Korean adolescent: Based on the Korea National Health and Nutrition Examination Survey 2007~2012

Kim SA, Jun S, Joung H

PURPOSE: The purpose of this study was to estimate dietary flavonoids intake of Korean adolescents. METHODS: Using data from the 2007-2012 Korean National Health and Nutrition Examination Survey, a total of...
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RNA-Seq De Novo Assembly and Differential Transcriptome Analysis of Korean Medicinal Herb Cirsium japonicum var. spinossimum

Roy NS, Kim JA, Choi AY, Ban YW, Park NI, Park KC, Yang HS, Choi IY, Kim S

Cirsium japonicum belongs to the Asteraceae or Compositae family and is a medicinal plant in Asia that has a variety of effects, including tumour inhibition, improved immunity with flavones, and...
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Estimated flavonoid intakes according to socioeconomic status of Korean adults based on the Korea National Health and Nutrition Examination Survey 2007~2012

Kim SA, Hei Y, Jun S, Wie GA, Shin S, Hong E, Joung H

PURPOSE: The purpose of this study was to estimate the dietary flavonoid intakes of Korean adults according to socioeconomic status. METHODS: Using data from the 2007~2012 Korea National Health and Nutrition...
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Flavone Biotransformation by Aspergillus niger and the Characterization of Two Newly Formed Metabolites

Mahmoud YA, Assawah SW, El-Sharkawy SH, Abdel-Salam A

  • KMID: 2411408
  • Mycobiology.
  • 2008 Jun;36(2):121-133.
Aspergillus niger isolated from Allium sativum was used at large scale fermentation (150 mg flavone/200 ml medium) to obtain suitable amounts of the products, efficient for identification. Then spectral analysis...
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Luteolin and luteolin-7-O-glucoside inhibit lipopolysaccharide-induced inflammatory responses through modulation of NF-kappaB/AP-1/PI3K-Akt signaling cascades in RAW 264.7 cells

Park CM, Song YS

  • KMID: 2313690
  • Nutr Res Pract.
  • 2013 Dec;7(6):423-429.
Luteolin is a flavonoid found in abundance in celery, green pepper, and dandelions. Previous studies have shown that luteolin is an anti-inflammatory and anti-oxidative agent. In this study, the anti-inflammatory...
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Composition of Flavonoids and Antioxidative Activity from Juice of Jeju Native Citrus Fruits during Maturation

Kim YD, Ko WJ, Koh KS, Jeon YJ, Kim SH

This study aims to evaluate the changes of flavonoid contents and antioxidants activity of Jeju native citrus fruits juice according to the harvest date. Flavonoids such as quercatagetin, narirutin, hesperidin...
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Eupatilin Inhibits Gastric Cancer Cell Growth by Blocking STAT3-Mediated VEGF Expression

Cheong JH, Hong SY, Zheng Y, Noh SH

  • KMID: 2372266
  • J Gastric Cancer.
  • 2011 Mar;11(1):16-22.
PURPOSE: Eupatilin is an antioxidative flavone and a phytopharmaceutical derived from Artemisia asiatica. It has been reported to possess anti-tumor activity in some types of cancer including gastric cancer. Eupatilin...
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Flavone Attenuates Vascular Contractions by Inhibiting RhoA/Rho Kinase Pathway

Baek I, Jeon SB, Song MJ, Yang E, Sohn UD, Kim IK

Our previous study demonstrated that flavone inhibits vascular contractions by decreasing the phosphorylation levelof the myosin phosphatase target subunit (MYPT1). In the present study, we hypothesized that flavone attenuates vascular...
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Differential modulation of zinc-stimulated p21(Cip/WAF1) and cyclin D1 induction by inhibition of PI3 kinase in HT-29 colorectal cancer cells

Oh SY, Park KS, Kim AJ, Choi KY

  • KMID: 1093594
  • Exp Mol Med.
  • 2002 Mar;34(1):27-31.
Activation of the extra cellular signal regulated kinase (ERK) pathway is involved in both proliferation and growth arrest of cells depending on intensity and duration of stimuli. In this study,...
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Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.

Shah BH, Rasheed H, Rahman IH, Shariff AH, Khan FL, Rahman HB, Hanif S, Saeed SA

  • KMID: 1457534
  • Exp Mol Med.
  • 2001 Dec;33(4):226-233.
Our recent studies have shown that co-activation of Gq and Gi proteins by 5-hydroxytryptamine (5-HT) and adrenaline show synergism in human platelet aggregation. This study was conducted to examine the...
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Role of Ras/ERK-dependent pathway in the erythroid differentiation of K562 cells

Kang CD, Do IR, Kim KW, Ahn BK, Kim SH, Chung BS, Jhun BH, Yoo MA

  • KMID: 1029935
  • Exp Mol Med.
  • 1999 Jun;31(2):76-82.
The chronic myelogenous leukemic K562 cell line carrying Bcr-Abl tyrosine kinase is considered as pluripotent hematopoietic progenitor cells expressing markers for erythroid, granulocytic, monocytic, and megakaryocytic lineages. Here we investigated the signaling modulations...
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