- Hypoxia Activates Toll-like Receptor 4 Signaling in Primary Mouse Hepatocytes Through the Receptor Clustering within Lipid Rafts
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Kim DH, Billiar TR
- KMID: 1963583
- J Korean Surg Soc.
- 2011 Mar;80(3):194-203.
- doi: 10.4174/jkss.2011.80.3.194
PURPOSE: Transient hypoxia is an initial event that accentuates ischemia/reperfusion (I/R) injury in the liver. Hepatic ischemia/reperfusion (I/R) injury is largely related to innate immunity via Toll-like receptor 4 (TLR4)... -
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- Lipid Raft Integrity Is Required for Survival of Triple Negative Breast Cancer Cells
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Badana A, Chintala M, Varikuti G, Pudi N, Kumari S, Kappala VR, Malla RR
- KMID: 2362923
- J Breast Cancer.
- 2016 Dec;19(4):372-384.
- doi: 10.4048/jbc.2016.19.4.372
PURPOSE: Lipid rafts are cholesterol enriched microdomains that colocalize signaling pathways involved in cell proliferation, metastasis, and angiogenesis. We examined the effect of methyl-β-cyclodextrin (MβCD)-mediated cholesterol extraction on the proliferation,... -
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