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The changes of fetal hemoglobin in preterm and small for gestational age newborn infants

Park EA, Kim GH

  • KMID: 2335061
  • J Korean Pediatr Soc.
  • 1993 Jul;36(7):919-927.
The fetal hemoglobin, which is structurally different from adult hemoglobin, has higher affinity for oxygen and higher resistance to denaturation with alkali than adult hemoglobin. Intrauterine growth retarded neonates have...
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Massive Fetomaternal Hemorrhage Diagnosed with High-performance Liquid Chromatography

Lee JY, Kim KH, Kong SG

Massive fetomaternal hemorrhage (FMH) is a major cause of unexplained fetal death and neonatal anemia. FMH can be diagnosed using the Kleihauer-Betke test or flow cytometry by identifying the presence...
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Maternal Anemia is Associated with Increased Fetal Erythropoietin Level

Seo YS, Roh JR, Oh JM, Yang SH, Jeong JH, Kim SW, Lee JH

  • KMID: 2269572
  • Korean J Obstet Gynecol.
  • 1998 Jun;41(6):1649-1653.
Maternal anemia during pregnancy is associated with low birth weight, preterm delivery and increased perinatal mortality. The level of fetal erythropoietin has been regarded as an index of prolonged fetal...
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Normal Value of Fetal hemoglobin Concentration in Children

Hong SG, Kang KW, Oh JH

  • KMID: 1946132
  • J Korean Pediatr Soc.
  • 1979 Jul;22(7):499-506.
A study of normal value of fetal hemoglobin concentration at each age in 1213 cases (852 patients, 361 normal children) who visited Chonnam university hospital from June 1977 to November...
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Hemoglobin F level in different hemoglobin variants

Olufemi AE, Sola OB, Oluwaseyi , Ajani RA, Olusoji MO, Olubunmi H

BACKGROUND: Fetal hemoglobin (HbF) levels in different hemoglobin variants in Osogbo, Nigeria, were estimated using two principal methods of estimation using existing information for HbF concentration and distribution of various...
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Fetal Erythrocyte Content of Normal Newborn Infants

Kim KB

  • KMID: 2335019
  • J Korean Pediatr Soc.
  • 1980 Dec;23(12):991-998.
The fetal erythrocyte (HbF-cell) content in the blood of the newborn infants was measuted in 945 newbo- rns whose gestational days were certain, among 2373 normal deliveries during the year...
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The usefulness of Doppler ultrasonography and the perinatal outcome of fetal anemia treated with intraumbilical venous transfusion

Baek SJ, Won HS, Shim JY, Lee PR, Kim A

OBJECTIVE: We undertook this study to determine the clinical characteristics and the prognostic factors of neonatal survival in patients with fetal anemia who were treated by intraumbilical venous transfusion (IUT). METHODS:...
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Transient Methemoglobinemia with Acidosis in Newborn

Kim HM

  • KMID: 2208546
  • J Korean Pediatr Soc.
  • 1994 Mar;37(3):416-421.
Methemoglobinemia is an uncommon clinical problem generally caused by inherited disorders of hemoglobin metabolism or environmental toxicity from oxidizing agents. Since methemoglobin has no oxigen carrying capacity, patient with severe...
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A Case of Neonatal Isoimmune Hemolytic Disease due to Anti-Mi(a) Antibody with Massive Fetomaternal Hemorrhage

Park SW, Park JH, Kim Y, You JH, Cho HM, Kim EY, Kim KS, Kim YW

Authors experienced a newborn treated with severe anemia transferred to our hospital due to pulselessness and apnea shortly after birth. Laboratory analysis of the blood on admission revealed hemoglobin 3.1...
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Latex Agglutination Test for Differentiating Neonatal Blood from the Maternal Blood in the Meconium

Park IK, Kim DA, Lee WS, Kim TY, Kim CR

  • KMID: 1560317
  • Korean J Lab Med.
  • 2002 Aug;22(4):242-245.
BACKGROUND: The Apt test is used for differentiating neonatal blood from the maternal blood in the meconium. The test requires a sufficient amount of blood to be detectable to the...
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Hematologic Characteristics and Hemoglobin Fraction Analysis by High Performance Liquid Chromatogaphy in Patients with Hypochromic Microcytosis: Trials for Detection of beta-thalassemia

Yang SE, Park CJ, Nah J, Min WK, Chi HS

  • KMID: 2082792
  • Korean J Lab Med.
  • 2005 Jun;25(3):145-151.
BACKGROUND: In Korea, more than 20 cases of beta-thalassemia have been reported up to date. To detect -thalassemia. Hemoglobin (Hb) fractions were measured in patients with hypochromic microcytosis, and we...
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Understanding the Molecular Basis of Juvenile Myelomonocytic Leukemia and Its Application for Novel Drugs Development

Jeon IS

To date, hematopoietic stem cell transplantation (HSCT) is the only choice of therapy for most patients with juvenile myelomonocytic leukemia (JMML). Relapse remains a major problem. Approximately 90% of patients...
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DNA-Protein Interaction of gamma-Globin Gene Promoter by Differentiation Inducers

Kim DI, Park JI, Kim IH

  • KMID: 2143367
  • Korean J Hematol.
  • 1999 Aug;34(3):436-444.
BACKGROUND: The K562 erythroleukemia cell line was used to study the molecular mechanisms regulating lineage commitment of hematopoietic cells. There are numerous similarities between the erythroid or megakaryocytic lineages. In...
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A Case of Long-term Survival with Autologous Recovery after Double Cord Blood Transplantation for Juvenile Myelomonocytic Leukemia

Lee HJ, Choi JY, Hong CR, Lee JW, Kang HJ, Park KD, Shin HY, Ahn HS

A 1.1 year old boy was admitted to the Seoul National University Children's Hospital because of incidental findings of hepatosplenomegaly, skin lesion and multiple intra- abdominal lymphadenopathies. Anemia and thrombocytopenia...
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A Case of Juvenile Myelomonocytic Leukemia in a Six Months Old Infant

Chang EA, Kim MK, Lim YA, Hyun BH, Kim SW, Park KH, Hong J

  • KMID: 2083421
  • Korean J Hematol.
  • 2000 May;35(2):189-194.
Myelodysplastic syndrome (MDS) in childhood is a rare hematologic malignancy and its classification has been the subject of some controversy. Cases of pediatric MDS are subdivided into those with features...
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Effect of Recombinant Human Erythropoietin on the Anemia of Premature Infants

Lee YA, Kim KS, Park YS, Moon HN, Hong CY

  • KMID: 1747682
  • J Korean Pediatr Soc.
  • 1996 May;39(5):631-640.
PURPOSE: To determine whether the prophylactic treatment with recombinant human erythropoietin(rHuEPO) for the anemia of prematurity would reduce the need for blood transfusions. METHODS: We randomly assigned 17 premature infants...
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Comparison of umbilical venous erythropoietin concentration between appropriate and small-for-gestational-age neonates of term pregnancy

Chun SH, Park MH

  • KMID: 2262486
  • Korean J Obstet Gynecol.
  • 2001 Dec;44(12):2296-2301.
OBJECTIVE: To evaluate the intrauterine hypoxic effect in term small-for-date (SGA) neonates by comparing the umbilical venous erythropoietin (EPO) concentration between appropriately-grown (AGA) and SGA neonates at delivery and to...
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Cytarabine Monotherapy as Bridging Treatment for Hematopoietic Stem Cell Transplantation in Children with Juvenile Myelomonocytic Leukemia

Suh WS, Cho MS, Lee JW, Jang PS, Chung NG, Jeong DC, Cho B, Kim HK

  • KMID: 2049276
  • Clin Pediatr Hematol Oncol.
  • 2012 Oct;19(2):86-91.
BACKGROUND: Mutations leading to hyperactivation of the RAS pathway play a critical role in the pathogenesis of juvenile myelomonocytic leukemia (JMML). Allogeneic hematopoietic stem cell transplantation (HSCT) is the only...
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Comparison of levels of umbilical venous erythropoietin and nucleated erythrocytes between appropriate and small for gestational age preterm neonates

Chun SH, Park MH, Kim YJ, Jeong KA, Lee KA

  • KMID: 2273716
  • Korean J Obstet Gynecol.
  • 2009 May;52(5):515-522.
OBJECTIVE: To evaluate any difference in levels of umbilical venous eryhthropoietin (EPO) and nucleated red blood cells (NRBC) between appropriate for gestational age (AGA) and small for gestational age (SGA)...
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Comparison of Capillary Electrophoresis with Cellulose Acetate Electrophoresis for the Screening of Hemoglobinopathies

Kim JE, Kim BR, Woo KS, Kim JM, Park JI, Han JY

BACKGROUND: beta-thalassemia is primarily found in individuals of Mediterranean and Southeast Asian ancestry. With rapid growth in the Southeast Asian segments of the Korean population, the geographic distribution of hemoglobinopathies...
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