- The role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistance
-
Yoon MS, Choi CS
- KMID: 2327670
- Exp Mol Med.
- 2016 Jan;48(1):e201.
- doi: 10.1038/emm.2015.93
Mammalian target of rapamycin (mTOR) controls cell growth and metabolism in response to nutrients, energy, and growth factors. Recent findings have placed the lysosome at the core of mTOR complex... -
- CITED
-
- Close
- SHARE
-
- Close
- Applications of stable, nonradioactive isotope tracers in in vivo human metabolic research
-
Kim IY, Suh SH, Lee IK, Wolfe RR
- KMID: 2327676
- Exp Mol Med.
- 2016 Jan;48(1):e203.
- doi: 10.1038/emm.2015.97
The human body is in a constant state of turnover, that is, being synthesized, broken down and/or converted to different compounds. The dynamic nature of in vivo kinetics of human... -
- CITED
-
- Close
- SHARE
-
- Close
- Charged MVB protein 5 is involved in T-cell receptor signaling
-
Wi SM, Min Y, Lee KY
- KMID: 2327679
- Exp Mol Med.
- 2016 Jan;48(1):e206.
- doi: 10.1038/emm.2015.102
Charged multivesicular body protein 5 (CHMP5) has a key role in multivesicular body biogenesis and a critical role in the downregulation of signaling pathways through receptor degradation. However, the role... -
- CITED
-
- Close
- SHARE
-
- Close
- Aspirin induces IL-4 production: augmented IL-4 production in aspirin-exacerbated respiratory disease
-
Kong SK, Kim BS, Uhm TG, Chang HS, Park JS, Park SW, Park CS, Chung IY
- KMID: 2327672
- Exp Mol Med.
- 2016 Jan;48(1):e202.
- doi: 10.1038/emm.2015.96
Aspirin hypersensitivity is a hallmark of aspirin-exacerbated respiratory disease (AERD), a clinical syndrome characterized by the severe inflammation of the respiratory tract after ingestion of cyclooxygenase-1 inhibitors. We investigated the... -
- CITED
-
- Close
- SHARE
-
- Close
- Isoproterenol increases histone deacetylase 6 expression and cell migration by inhibiting ERK signaling via PKA and Epac pathways in human lung cancer cells
-
Lim JA, Juhnn YS
- KMID: 2327677
- Exp Mol Med.
- 2016 Jan;48(1):e204.
- doi: 10.1038/emm.2015.98
Stress conditions are correlated with tumor growth, progression and metastasis. We hypothesized that stress signals might affect tumor progression via epigenetic control of gene expression and investigated the effects of... -
- CITED
-
- Close
- SHARE
-
- Close
- CB2 receptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinson's disease
-
Chung YC, Shin WH, Baek JY, Cho EJ, Baik HH, Kim SR, Won SY, Jin BK
- KMID: 2327678
- Exp Mol Med.
- 2016 Jan;48(1):e205.
- doi: 10.1038/emm.2015.100
The cannabinoid (CB2) receptor type 2 has been proposed to prevent the degeneration of dopamine neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice. However, the mechanisms underlying CB2 receptor-mediated neuroprotection in MPTP mice... -
- CITED
-
- Close
- SHARE
-
- Close
