- Nerve growth factor(NGF) induces mRNA expression of the new transcription factor protein p48ZnF
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Heese K, Nagai Y, Sawada T
- KMID: 1380207
- Exp Mol Med.
- 2004 Apr;36(2):130-134.
Apoptosis, the cell's intrinsic death program, plays a crucial role in the regulation of tissue homeostasis, and abnormal inhibition of apoptosis is an indicator of cancer and autoimmune diseases, whereas... -
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- Application of DNA chip techniques for Yq microdeletion analysis in infertile males
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Lee S, Joo HS, Lee SH, Park JE, Kim JM, Hwang JH, Cho KS, Hwang SY
- KMID: 1380213
- Exp Mol Med.
- 2004 Apr;36(2):179-184.
Our aim was to apply DNA chip technology as a diagnostic tool in infertility research and clinics. Six loci, including a sex-determining region on the Y chromosome and five sequence-tagged... -
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- Trp-Lys-Tyr-Met-Val-Met stimulates phagocytosis via phospho-lipase D-dependent signaling in mouse dendritic cells
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Lee HY, Kang HK, Jo EJ, Kim JI, Lee YN, Lee SH, Park YM, Ryu SH, Kwak JY, Bae YS
- KMID: 1380208
- Exp Mol Med.
- 2004 Apr;36(2):135-144.
Dendritic cells (DCs) play a key role in activating the immune response against invading pathogens as well as dying cells or tumors. Although the immune response can be initiated by... -
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- Phosphorylation of phospholipase D1 and the modulation of its interaction with RhoA by cAMP-dependent protein kinase
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Jang MJ, Lee MJ, Park HY, Bae YS, Min DS, Ryu SH, Kwak JY
- KMID: 1380212
- Exp Mol Med.
- 2004 Apr;36(2):172-178.
Agents that elevate cellular cAMP are known to inhibit the activation of phospholipase D (PLD). We investigated whether PLD can be phosphorylated by cAMP-dependent protein kinase (PKA) and PKA-mediated phosphorylation... -
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- Proteomic analysis of human cerebral cortex in epileptic patients
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Eun JP, Choi HY, Kwak YG
- KMID: 1380214
- Exp Mol Med.
- 2004 Apr;36(2):185-191.
Epilepsy affects more than 0.5% of the world population and is known to be associated with a large genetic component eliciting an electrical hyperexcitability in the central nervous system. However,... -
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- Inactivation patterns of p16/INK4A in oral squamous cell carcinomas
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Lee JK, Kim MJ, Hong SP, Hong SD
- KMID: 1380211
- Exp Mol Med.
- 2004 Apr;36(2):165-171.
The p16/INK4A is one of the major target genes in carcinogenesis and its inactivation has frequently been reported in other types of tumors. The purpose of this study is to... -
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- Evidence that the fully assembled capsid of Leishmania RNA virus 1-4 possesses catalytically active endoribonuclease activity
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Ro YT, Kim EJ, Lee HI, Saiz M, Jr RC, Patterson
- KMID: 1380209
- Exp Mol Med.
- 2004 Apr;36(2):145-156.
In this study, Leishmania RNA virus 1-4 (LRV1-4) particles purified from host Leishmania guyanensis promastigotes were examined for capsid endoribonuclease. Temperature optimum for the endoribonulease activity was found to be... -
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- Association study of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with myocardial infarction
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Iqbal MP, Mahmood S, Mehboobali N, Ishaq M, Fatima T, Parveen S, Frossard P
- KMID: 1380204
- Exp Mol Med.
- 2004 Apr;36(2):110-115.
The angiotensin converting enzyme (ACE) is a strong candidate gene for myocardial infarction (MI). Insertion-deletion dimorphism in intron 16 of this gene has been inconclusively found to be associated with... -
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- Involvement of ROS and JNK1 in selenite-induced a poptosisin Chang liver cells
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Kim YS, Jhon DY, Lee KY
- KMID: 1380210
- Exp Mol Med.
- 2004 Apr;36(2):157-164.
Selenium is a dietary essential trace nutrient with important biological roles. Selenocompounds were reported to induce apoptosis in many types of tumor cells. In this study, we investigated the signaling... -
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- Phospholipase D is involved in oxidative stress-induced migration of vascular smooth muscle cells via tyrosine phosphorylation and protein kinase C
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Kim J, Min G, Bae YS, Min DS
- KMID: 1380203
- Exp Mol Med.
- 2004 Apr;36(2):103-109.
Oxidative stress has been implicated in mediation of vascular disorders. In the presence of vanadate, H2O2 induced tyrosine phosphorylation of PLD1, protein kinase C-a (PKC-a), and other unidentified proteins in... -
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- Microsatellite instability and its correlation with clinicopathological features in a series of thyroid tumors prevalent in iodine deficient areas
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Vaish M, Mishra A, Kaushal M, Mishra SK, Mittal B
- KMID: 1380206
- Exp Mol Med.
- 2004 Apr;36(2):122-129.
Thyroid tumors display diverse spectrum of histopathological groups with geographic variation in its prevalence. Influence of iodine deficiency (a major causative factor) in its etiology, prevalence, or aggressiveness is debatable... -
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- Methylenetetrahydrofolate reductase polymorphism, diet, and breast cancer in Korean women
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Lee SA, Kang D, Nishio H, Lee MJ, Kim DH, Han W, Yoo KY, Ahn SH, Choe KJ, Hirvonen A, Noh DY
- KMID: 1380205
- Exp Mol Med.
- 2004 Apr;36(2):116-121.
To evaluate the interactive effect of methylenetetrahydrofolate reductase (MTHFR) genotype and dietary factors on the development of breast cancer, a hospital based case-control study was conducted in South Korean study... -
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