Skip Navigation
Skip to contents
Filter

ARTICLE TYPE

PUBLICATION DATE

17 results
Display

Comparison of oligonucleotide-microarray and serial analysis of gene expression (SAGE) in transcript profiling analysis of megakaryocytes derived from CD34+ cells

Kim HL

  • KMID: 1093620
  • Exp Mol Med.
  • 2003 Oct;35(5):460-466.
For the comprehensive analysis of transcript expression, the array-based hybridization analysis and the serial analysis of gene expression (SAGE) are commonly used platforms. The SAGE is based on a high-throughput...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients

Savli H, Sirma S, Nagy B, Aktan M, Dincol G, Ozbek U

  • KMID: 1093619
  • Exp Mol Med.
  • 2003 Oct;35(5):454-459.
All-trans retinoic acid (ATRA) treatment of the acute promyelocytic leukemia (APL) have subsequently resulted in cell apoptosis, but the molecular mechanism of this effect remains elusive. In order to understand...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Impaired phosphorylation and mis-localization of Bub1 and BubR1 are responsible for the defective mitotic checkpoint function in Brca2-mutant thymic lymphomas

Lee H

  • KMID: 1093618
  • Exp Mol Med.
  • 2003 Oct;35(5):448-453.
Breast cancer susceptibility gene, BRCA2, is a tumor suppressor and individuals who inherit one defected copy of BRCA2 allele experience early onset breast cancer or ovarian cancer accompanied by the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
CD99 type II is a determining factor for the differentiation of primitive neuroectodermal cells

Lee EJ, Lee HG, Park SH, Choi EY, Park SH

  • KMID: 1093617
  • Exp Mol Med.
  • 2003 Oct;35(5):438-447.
CD99 is a 32-kDa cell surface molecule present on thymocytes, peripheral T cells, many other hematopoietic stem cells and somatic cells were implicated in cell-cell adhesion and cell-activation phenomena. Two...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
NF-kappaB is involved in the TNF-alpha induced inhibition of the differentiation of 3T3-L1 cells by reducing PPARg expression

Chae GN, Kwak SJ

  • KMID: 1093616
  • Exp Mol Med.
  • 2003 Oct;35(5):431-437.
TNF-alpha, a trimeric cytokine, was known to inhibit differention of preadipocytes to adipocytes. In the present study, we investigated signal mediators working downstream of TNF-alpha using murine 3T3-L1 cells. TNF-alpha...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Biochemical characterizations reveal different properties between CDK4/cyclin D1 and CDK2/cyclin A

Kim DM, Yang K, Yang BS

  • KMID: 1093615
  • Exp Mol Med.
  • 2003 Oct;35(5):421-430.
CDK2 and CDK4 known promoter of cell cycling catalyze phosphorylation of RB protein. Enzyme specificity between two CDKs that work at a different cell cycle phase is not clearly understood....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
High efficiency transduction of human VEGF(165)into human skeletal myoblasts: in vitro studies

Ye L, Haider HK, Jiang S, Ge R, Law PK, Sim EK

  • KMID: 1093614
  • Exp Mol Med.
  • 2003 Oct;35(5):412-420.
We report the transduction of human VEGF(165)gene into human myoblast and characterization of the transduced myoblasts for transduction and expression efficiency. Human myoblasts were assessed by immunostaining for desmin expression....
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Identification of amyloid beta-peptide responsive genes by cDNA microarray technology: Involvement of RTP801 in amyloid beta-peptide toxicity

Kim JR, Lee SR, Chung HJ, Kim S, Baek SH, Kim JH, Kim YS

  • KMID: 1093613
  • Exp Mol Med.
  • 2003 Oct;35(5):403-411.
Amyloid beta-peptide (Abeta), a causative molecule in the pathogenesis of Alzheimer's disease and the main component of senile plaques, is known to be neurotoxic in vitro and in vivo. The...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Genomic organization and expression of parkin in Drosophila melanogaster

Bae YJ, Park KS, Kang SJ

  • KMID: 1093612
  • Exp Mol Med.
  • 2003 Oct;35(5):393-402.
We report here the isolation, characterization on genomic structure and expression of the D. melanogaster homolog of human parkin. The 2,122 bp parkin gene sequence contains six exons that form...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
B cells activated in the presence of Th1 cytokines inhibit osteoclastogenesis

Choi Y, Kim JJ

  • KMID: 1093611
  • Exp Mol Med.
  • 2003 Oct;35(5):385-392.
Host immune response has been considered as an important disease-modifying factor of periodontitis, however, which immune cell(s) or factor(s) are involved in the destruction of periodontium remains unclear. Previously, we...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Dexamethasone-induced differentiation of pancreatic AR42J cell involves p21(waf1/cip1)and MAP kinase pathway

Eum WS, Li MZ, Sin GS, Choi SY, Park JB, Lee JY, Kwon HY

  • KMID: 1093610
  • Exp Mol Med.
  • 2003 Oct;35(5):379-384.
Dexamethasone converts pluripotent pancreatic AR42J cells into exocrine cells expressing digestive enzymes. In order to address molecular mechanism of this differentiation, we have investigated the role of mitogen-activated protein (MAP)...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Grape extracts suppress the formation of preneoplastic foci and activity of fatty acid synthase in rat liver

Kweon S, Kim Y, Choi H

  • KMID: 1093609
  • Exp Mol Med.
  • 2003 Oct;35(5):371-378.
This study was conducted to examine the effects of dietary grape extracts on preneoplastic foci formation in rat hepatocarcinogenesis, and related hepatic enzymes. Male Sprague-Dawley rats were fed basal diet...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Chronic activation of CREB and p90RSK in human epileptic hippocampus

Park SA, Kim TS, Choi KS, Park HJ, Heo K, Lee BI

  • KMID: 1093608
  • Exp Mol Med.
  • 2003 Oct;35(5):365-370.
Mesial temporal lobe epilepsy (MTLE) is associated with severe neuronal death and reactive gliosis in hippocampus. However, the molecular mechanisms underlying these pathological changes remain unanswered. ERK has been reported...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Soluble glucocorticoid-induced TNF receptor (sGITR) induces inflammation in mice

Shin HH, Kim SG, Lee MH, Suh JH, Kwon BS, Choi HS

  • KMID: 1093607
  • Exp Mol Med.
  • 2003 Oct;35(5):358-364.
Glucocorticoid-induced TNF receptor (GITR) was a new member of the TNF/nerve growth factor receptor (TNFR/ NGFR) family and induced in murine T cells by dexamathasone. Recombinant soluble GITR (sGITR) induced...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells

Joung YH, Park JH, Park T, Lee CS, Kim OH, Ye SK, Yang UM, Lee KJ, Yang YM

  • KMID: 1093606
  • Exp Mol Med.
  • 2003 Oct;35(5):350-357.
STATs (signal transducers and activators of transcription) are proteins with dual functions: signal transducers in the cytoplasm and transcriptional activators in the nucleus. STAT proteins act as transcription factors activated...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Gene expression profiling of oxidative stress on atrial fibrillation in humans

Kim YH, Lee JH, Lim DS, Shim WJ, Ro YM, Park GH, Becker KG, Cho-Chung , Kim MK

  • KMID: 1093605
  • Exp Mol Med.
  • 2003 Oct;35(5):336-349.
Atrial Fibrillation (AF) is thought be caused by oxidative stress. Oxidative stress at the cellular level results from many factors, including exposure to alcohol, medications, cold, toxins or radiation. In...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Phagocytosis induces superoxide formation and apoptosis in macrophages

Park JB

  • KMID: 1093604
  • Exp Mol Med.
  • 2003 Oct;35(5):325-335.
Phagocytosis by inflammatory cells is an essential step and a part of innate immunity for protection against foreign pathogens, microorganism or dead cells. Phagocytosis, endocytotic events sequel to binding particle...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2020 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr