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Intestinal parasitic infections in the residents of an emigration camp in Tijuana, Mexico

Huh S, Ahn C, Chai JY

We examined stool specimens of the residents in the emigration camp in Tijuana, Mexico for helminth eggs or protozoan cysts with formalin-ethyl acetate concentration method in February and July 1992....
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Introns: The Functional Benefits of Introns in Genomes

Jo BS, Choi SS

The intron has been a big biological mystery since it was first discovered in several aspects. First, all of the completely sequenced eukaryotes harbor introns in the genomic structure, whereas...
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Alternative Splicing and Its Impact as a Cancer Diagnostic Marker

Kim YJ, Kim HS

Most genes are processed by alternative splicing for gene expression, resulting in the complexity of the transcriptome in eukaryotes. It allows a limited number of genes to encode various proteins...
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Bioinformatics Analysis of Hsp20 Sequences in Proteobacteria

Heine M, Chandra SB

  • KMID: 2166438
  • Genomics Inform.
  • 2009 Mar;7(1):26-31.
Heat shock proteins are a class of molecular chaperones that can be found in nearly all organisms from Bacteria, Archaea and Eukarya domains. Heat shock proteins experience increased transcription during...
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Obesity and ER Stress

Koo SH

  • KMID: 2270933
  • Korean J Obes.
  • 2011 Jun;20(2):45-50.
Endoplastic reticulum (ER) is one of the cellular organelle found in all eukaryotes. It plays a critical role in the protein folding, lipid and sterol biosynthesis, and the storage of...
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Evolutionary Signature of Information Transfer Complexity in Cellular Membrane Proteomes

Kim JM, Kim BG, Oh SJ

  • KMID: 2053230
  • Genomics Inform.
  • 2009 Jun;7(2):111-121.
Cell membrane proteins play crucial roles in the cell's molecular interaction with its environment and within itself. They consist of membrane-bound proteins and many types of transmembrane (TM) proteins such...
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Cell cycle checkpoint control

Murakami H, Okayama H

  • KMID: 2128619
  • Exp Mol Med.
  • 1997 Mar;29(1):1-11.
Genetic instability is considered to be a major driving force of malignancy of cancer cells, and at least some of cancer-associated genetic instability is known to be caused by defects...
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Alternative Polyadenylation in Human Diseases

Chang JW, Yeh HS, Yong J

Varying length of messenger RNA (mRNA) 3′-untranslated region is generated by alternating the usage of polyadenylation sites during pre-mRNA processing. It is prevalent through all eukaryotes and has emerged as...
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Eukaryotic DNAJ/K Database: A Comprehensive Phylogenomic Analysis Platform for the DNAJ/K Family

Cheong K, Choi J, Choi J, Park J, Jang S, Lee YH

Proteins in DNAJ/K families are ubiquitous, from prokaryotes to eukaryotes, and function as molecular chaperones. For systematic phylogenomics of the DNAJ/K families, we developed the Eukaryotic DNAJ/K Database (EDD). A...
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Mechanisms of Uniparental Mitochondrial DNA Inheritance in Cryptococcus neoformans

Gyawali R, Lin X

  • KMID: 2312648
  • Mycobiology.
  • 2011 Dec;39(4):235-242.
In contrast to the nuclear genome, the mitochondrial genome does not follow Mendelian laws of inheritance. The nuclear genome of meiotic progeny comes from the recombination of both parental genomes,...
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Regulation of Protein Degradation by Proteasomes in Cancer

Jang HH

Imbalance of protein homeostasis (proteostasis) is known to cause cellular malfunction, cell death, and diseases. Elaborate regulation of protein synthesis and degradation is one of the important processes in maintaining...
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Conserved Roles of MonA in Fungal Growth and Development in Aspergillus Species

Son YE, Park HS

MonA is a subunit of a guanine nucleotide exchange factor that is important for vacuole passing and autophagy processes in eukaryotes. In this study, we characterized the function of MonA,...
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A Survey of Intestinal Protozoan Infections among Gastroenteritis Patients during a 3-Year Period (2004-2006) in Gyeonggi-do (Province), South Korea

Huh JW, Moon SG, Lim YH

The incidence and etiology of parasite-associated gastroenteritis during 2004-2006 in Gyeonggi-do (province), South Korea was determined by means of antigen detection ELISA on 6,071 stool specimens collected from 6 general...
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CysQ of Cryptosporidium parvum, a Protozoa, May Have Been Acquired from Bacteria by Horizontal Gene Transfer

Lee JY, Kim S

Horizontal gene transfer (HGT) is the movement of genetic material between kingdoms and is considered to play a positive role in adaptation. Cryptosporidium parvum is a parasitic protozoan that causes...
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DEAD/DExH-Box RNA Helicases in Selected Human Parasites

Marchat LA, Arzola-Rodriguez SI, Hernandez-de la Cruz O, Lopez-Rosas I, Lopez-Camarillo C

DEAD/DExH-box RNA helicases catalyze the folding and remodeling of RNA molecules in prokaryotic and eukaryotic cells, as well as in many viruses. They are characterized by the presence of the...
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Modulating cellular balance of Rps3 mono-ubiquitination by both Hel2 E3 ligase and Ubp3 deubiquitinase regulates protein quality control

Jung Y, Kim HD, Yang HW, Kim HJ, Jang CY, Kim J

When a ribosome complex is stalled during the translation elongation process in eukaryotes, the mono-ubiquitination of Rps3 has recently been shown to be critical to ribosome quality control. We have...
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Examining the Gm18 and m1G Modification Positions in tRNA Sequences

Subramanian M, Srinivasan T, Sudarsanam D

The tRNA structure contains conserved modifications that are responsible for its stability and are involved in the initiation and accuracy of the translation process. tRNA modification enzymes are prevalent in...
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Screening of Differentially Expressed Genes between PC12 Cells and A123.7 Cells

Baik SY, Chai YG, Yang BH

  • KMID: 2334593
  • J Korean Soc Biol Psychiatry.
  • 1999 Jul;6(1):67-73.
The cAMP-dependent protein kinase(PKA) is an intracellular enzyme with serine-threonine kinase activity that plays a key role in cell growth, differentiation, and apoptosis in eukaryotes. In order to understand the...
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In Silico Sequence Analysis Reveals New Characteristics of Fungal NADPH Oxidase Genes

Detry N, Choi J, Kuo HC, Asiegbu FO, Lee YH

NADPH oxidases (Noxes), transmembrane proteins found in most eukaryotic species, generate reactive oxygen species and are thereby involved in essential biological processes. However, the fact that genes encoding ferric reductases...
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The Change of Telomerase Activity in the Developmental Stages of the Rat Urinary System

Lee SD, Bahk JY

  • KMID: 2290388
  • Korean J Urol.
  • 1999 Nov;40(11):1411-1418.
PURPOSE: Telomeres define the natural ends of linear chromosomes and their sequence organization is highly conserved in the majority of eukaryotes. Telomerase is a ribonucleoprotein involved in maintaining telomere length...
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