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Effects of Ylang-Ylang Oil on the Relaxation of Rat Bladder Muscles

Yang HM, Youn WY, Kim HJ

  • KMID: 2330464
  • J Korean Continence Soc.
  • 2002 Jun;6(1):33-42.
PURPOSE: In cases of overactive bladders, especially hyperreflexic neurogenic bladders, that arise in patients with spine disorder above sacral micturition center, current primary treatment modalities include the administration of anticholinergics...
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Transthyretin Stimulates Autooxidation of Reduced Glutathione

Park JK, Jung S, Kim JH, Kim SH, Kang SS, Lee JH, Ahn BW

  • KMID: 1673072
  • J Korean Neurosurg Soc.
  • 1994 Aug;23(8):916-923.
When reduced glutathione(GSH) was incubated at neutral pH and at 37degrees, its concentration decteased slowly with formation of oxidized glutathione(GSSG). Autooxidation of GSH was accelerated by Cu2+ and Hg2+, but...
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Arachidonic Acid Activates K+-Cl--cotransport in HepG2 Human Hepatoblastoma Cells

Lee YS

K+-Cl--cotransport (KCC) has been reported to have various cellular functions, including proliferation and apoptosis of human cancer cells. However, the signal transduction pathways that control the activity of KCC are...
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Significance of Vesicle-Associated Membrane Protein 8 Expression in Predicting Survival in Breast Cancer

Yuan M, Liao J, Luo J, Cui M, Jin F

PURPOSE: Vesicle-associated membrane protein 8 (VAMP8) is a soluble N-ethylmaleimide-sensitive factor receptor protein that participates in autophagy by directly regulating autophagosome membrane fusion and has been reported to be involved...
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Alteration of Immunoreactivity for SNARE Proteins in the Rat Hippocampus after Middle Cerebral Artery Occlusion

Park JS, Huh PW, Jung YJ, Park SJ, Lee KE

  • KMID: 2285298
  • Korean J Physiol Pharmacol.
  • 2004 Jun;8(3):141-146.
Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) proteins, composed of two presynaptic membrane proteins [synaptosomal-associated protein of 25 kDa (SNAP-25) and syntaxin] and a presynaptic vesicular protein [vesicle-associated membrane protein...
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Effect of Tetraethylammonium on the Contractile Reponse in the Isolated Rat Phrenic: Hemidiaphra

Lee HJ, Lee KS, Song YK, Kim TY, Choi BK

BACKGROUND: Recently, the phannacologic and therapeutic significance of various types of potassium channels are being realized. Thus it was attempted to delineate the role of voltage-gated K+ -channels on the...
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A Novel Carbamoyloxy Arylalkanoyl Arylpiperazine Compound (SKL-NP) Inhibits Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channel Currents in Rat Dorsal Root Ganglion Neurons

Chung G, Kim TH, Shin H, Chae E, Yi H, Moon H, Kim HJ, Kim JS, Jung SJ, Oh SB

In this study, we determined mode of action of a novel carbamoyloxy arylalkanoyl arylpiperazine compound (SKL-NP) on hyperpolarization-activated cyclic nucleotide-gated (HCN) channel currents (Ih) that plays important roles in neuropathic...
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Thiol-dependent Redox Mechanisms in the Modification of ATP-Sensitive Potassium Channels in Rabbit Ventricular Myocytes

Han J, Kim N, Cuong DV, Kim C, Kim E

  • KMID: 1607349
  • Korean J Physiol Pharmacol.
  • 2003 Feb;7(1):15-23.
Cellular redox state is known to be perturbed during ischemia and that Ca2+ and K+ channels have been shown to have functional thiol groups. In this study, the properties of...
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Interaction of forskolin with the effect of N-6-cyclopentyladenosine on norepinephrine release in rat hippocampus

Choi BK, Kim DK, Son Y, Yang UJ

  • KMID: 2285166
  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):225-231.
As it has been reported that the depolarization-induced norepinephrine (NE) release is modulated by activation of presynaptic A-1-adenosine heteroreceptor and various lines of evidence indicate the involvement of adenylate cyclase system in A-1-adenosine...
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Reactive Oxygen Species and Nitrogen Species Differentially Regulate Neuronal Excitability in Rat Spinal Substantia Gelatinosa Neurons

Lee HI, Park AR, Chun SW

Reactive oxygen species (ROS) and nitrogen species (RNS) are implicated in cellular signaling processes and as a cause of oxidative stress. Recent studies indicate that ROS and RNS are important...
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Effect of Rhodiola Sachalinensis Administration and Endurance Exercise on Insulin Sensitivity and Expression of Proteins Related with Glucose Transport in Skeletal Muscle of Obese Zucker Rat

Oh JK, Shin YO, Jung HJ, Lee JE

  • KMID: 2269974
  • Korean J Nutr.
  • 2006 Jun;39(4):323-330.
Peripheral insulin resistance in obese/type II diabetes animals results from an impairment of insulin-stimulated glucose uptake into skeletal muscle. Insulin stimulate the translocation of GLUT4 from intracellular location to the...
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Regulatory role of cyclic nucleotides in non-adrenergic non-cholinergic relaxation of lower esophageal sphincter from dogs

Kim YT, Rhim BY

  • KMID: 2285174
  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):303-313.
The role of the lower esophageal sphincter (LES) is characterized by the ability to maintain tone and to relax allowing the passage of a bolus. It is known that LES relaxation during...
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Restoration of Cdk5, TrkB and Soluble N-ethylmaleimide-Sensitive Factor Attachment Protein Receptor Proteins after Chronic Methylphenidate Treatment in Spontaneous Hypertensive Rats, a Model for Attention-Deficit Hyperactivity Disorder

Kim Y, Jeon S, Jeong HJ, Lee SM, Peña ID, Kim HJ, Han DH, Kim BN, Cheong JH

OBJECTIVE: Synaptic vesicle mobilization and neurite outgrowth regulation molecules were examined in modulation of effects of methylphenidate (MPH) in Spontaneous Hypertensive Rats (SHRs), a model for attention-deficit hyperactivity disorder (ADHD). METHODS:...
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