- Evidence for estrogen receptor expression during medullary bone formation and resorption in estrogen-treated male Japanese quails (Coturnix coturnix japonica)
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Hiyama S, Sugiyama T, Kusuhara S, Uchida T
- KMID: 1389760
- J Vet Sci.
- 2012 Sep;13(3):223-227.
- doi: 10.4142/jvs.2012.13.3.223
The temporal expression of estrogen receptor (ER)-alpha and ER-beta mRNA was examined in male Japanese quails. Femurs of quails receiving 17beta-estradiol underwent RTPCR and histochemical analysis 1 to 15 days... -
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- The Growth and Pubertal Development in Female Mice with Tissue-specific Knock out of Estrogen Receptor
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Shim KS
- KMID: 2384062
- J Korean Soc Pediatr Endocrinol.
- 2011 Aug;16(2):67-72.
The roles of estrogen and its receptors are important for control of puberty, pubertal growth spurt, epiphyseal fusion of long bone, and accretion of bone mineral content in adolescent. But,... -
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- Comparison of estrogen receptor beta expression between breast cancer and normal mammary tissue and relationship with clinicopathological factors
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Kim SI, Park SO, Jung SY, Yang WI, Park BW
- KMID: 2174950
- J Breast Cancer.
- 2005 Sep;8(3):99-104.
- doi: 10.4048/jbc.2005.8.3.99
PURPOSE: To verify the difference of estrogen receptor beta (ER beta) expression between breast cancer and normal mammary tissue and the roles of ER beta in prognosis of breast cancer,... -
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- Gender-specific Colorectal Cancer: Epidemiologic Difference and Role of Estrogen
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Kim HM, Kim HS
- KMID: 1791876
- Korean J Gastroenterol.
- 2014 Apr;63(4):201-208.
- doi: 10.4166/kjg.2014.63.4.201
Gender difference in the incidence of colorectal cancer is well known and has been supported by various epidemiologic studies. In Korea, women have lower incidence of colorectal cancer and adenoma,... -
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- Role of Estrogen Receptor-alpha in the Regulation of Claudin-6 Expression in Breast Cancer Cells
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Yafang L, Qiong W, Yue R, Xiaoming X, Lina Y, Mingzi Z, Ting Z, Yulin L, Chengshi Q
- KMID: 2175638
- J Breast Cancer.
- 2011 Mar;14(1):20-27.
- doi: 10.4048/jbc.2011.14.1.20
PURPOSE: In our previous studies we showed that upregulating claudin-6 (CLDN6) expression may contribute to preventing breast cancer, and that 17beta-estradiol induces a concentration- and time-related effect on CLDN6 mRNA... -
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- Expression of estrogen receptor beta, estrogen receptor alpha and cyclooxygenase II in advanced breast cancer
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Baek JM, Sung GY, Lee DS, Chun KH, Lee DH, Seo YJ, Choi SH, Park WC, Kim JS, Song BJ, Oh SJ, Kim W, Park IY, Jung SS, Lim KW, Won JM, Chun CS, Lee JH, Kim JA
- KMID: 1573949
- J Breast Cancer.
- 2005 Jun;8(2):45-51.
- doi: 10.4048/jbc.2005.8.2.45
PURPOSE: Although the role of the estrogen receptor alpha (ER alpha, previously called the estrogen receptor) in breast cancer is well established, that of the second human estrogen receptor (ER),... -
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- The Relationship Between the Expression of Estrogen Receptor beta and Recurrence in Breast Cancer
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Kang SH, Choi JE, Lee SJ
- KMID: 2320056
- Yeungnam Univ J Med.
- 2011 Dec;28(2):153-164.
BACKGROUND: It has been reported that estrogen receptor beta (ERbeta) mRNA expression was down-regulated during carcinogenesis and was inversely related to estrogen receptor alpha (ERalpha) expression in breast cancer. The... -
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- Role of co-expression of estrogen receptor beta and Ki67 in prostate adenocarcinoma
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Azizan N, Hayati F, Tizen NM, Farouk WI, Masir N
- KMID: 2414755
- Investig Clin Urol.
- 2018 Jul;59(4):232-237.
- doi: 10.4111/icu.2018.59.4.232
PURPOSE: To evaluate the expression of estrogen receptor (ER)-beta and Ki67 in prostate cancer and study their relationship. MATERIALS AND METHODS: We analyzed 101 cases of prostate adenocarcinoma diagnosed from January... -
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- Up-regulation of P13K/Akt Signaling by 17 beta-estradiol through Activation of Estrogen Receptor-alpha in Breast Cancer Cells
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So MC, Hwang HP, Lee CH, Youn HJ, Jung SH, Kim JC
- KMID: 2286625
- J Breast Cancer.
- 2006 Jun;9(2):91-97.
- doi: 10.4048/jbc.2006.9.2.91
PURPOSE: Estrogen stimulates cell proliferation in breast cancer, the biological effects of which are mediated through two intracellular receptors: estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta). However, the actual role... -
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- The effect of growth factor receptor HER2 on the estrogen receptor transcriptional activities and its implications
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Heo MK, Park SO, Jung SY, Kim SI, Park BW
- KMID: 2174951
- J Breast Cancer.
- 2005 Sep;8(3):105-112.
- doi: 10.4048/jbc.2005.8.3.105
PURPOSE: Until recently, breast cancer carcinogenesis has not been fully understood, but the roles of estrogen receptors(ERs) and growth factor receptors(like HER2) were known to be important. Growth factors have... -
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- Expression of estrogen receptor (ER)alpha, ERbeta and insulin-like growth factor binding protein related peptide-1 messenger ribonucleic acid in uterine leiomyoma and normal myometrium
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Lim KS, Kim JG
- KMID: 2262658
- Korean J Obstet Gynecol.
- 2002 Mar;45(3):391-398.
OBJECTIVE: To evaluate a possible involvement of estrogen receptor (ER)alpha, ER beta and insulin-like growth factor binding protein related peptide-1 (IGFBPrp-1) in the growth of leiomyoma. METHODS: The relative expressions of... -
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- Functions and physiological roles of two types of estrogen receptors, ERalpha and ERbeta, identified by estrogen receptor knockout mouse
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Lee HR, Kim TH, Choi KC
- KMID: 1436696
- Lab Anim Res.
- 2012 Jun;28(2):71-76.
- doi: 10.5625/lar.2012.28.2.71
Estrogens, a class of steroid hormones, regulate the growth, development, and physiology of the human reproductive system. Estrogens also involve in the neuroendocrine, skeletal, adipogenesis, and cardiovascular systems. Estrogen signaling... -
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- Expression of Estrogen Receptor-beta mRNA in Various Mammary Tissues
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Park BW, Kim KS, Heo MK, Hong SW, Kim SI, Lee KS
- KMID: 2006610
- J Korean Breast Cancer Soc.
- 2003 Jun;6(2):75-80.
- doi: 10.4048/jkbcs.2003.6.2.75
PURPOSE: Estrogen signal transduction plays very important roles in both normal mammary development and neoplastic progression. Since the discovery of estrogen receptor-beta (ER-beta) there have been many controversial reports on... -
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- Study on the Role of Estrogen Receptor-Alpha in Yak-Kong and Soybean Induced Proliferation of MG-63 Human Osteoblastic Cells
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Um SJ, Kang IS, Cho Y
- KMID: 2269895
- Korean J Nutr.
- 2005 Sep;38(7):512-520.
Phytoestrogens, especially Yak-kong or soybean-derived isoflavones have been traditionally used as a supplement of estrogen for preventing postmenopausal osteoporosis in oriental folk medicine. In a previous study, we demonstrated that... -
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- The Clinical Significance of the Estrogen Receptor beta Expression for Endocrine Therapy in Patients with ERalpha-negative and Progesterone Receptor-positive Breast Carcinoma
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Park MH, Ryu HS, Ro HW, Cho JS, Yoon JH, Jegal YJ, Kim JH, Lee JS, Park CS
- KMID: 2242006
- J Breast Cancer.
- 2009 Sep;12(3):156-162.
- doi: 10.4048/jbc.2009.12.3.156
PURPOSE: Estrogen receptor (ER) is the key therapeutic target in breast cancer. ERbeta has recently been identified to be distinct from ERalpha. In contrast to ERalpha, the functions of ERbeta... -
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- Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-beta in colorectal cells
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He YQ, Sheng JQ, Ling XL, Fu L, Jin P, Yen L, Rao J
- KMID: 1402316
- Exp Mol Med.
- 2012 Dec;44(12):723-732.
Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors.... -
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- Pathologic Characteristics of Ovarian Hemorrhagic Polycyst in Estrogen Receptor-alpha (ERalpha) Knockout Mice and Roles of ERalpha in Hemorrhagic Polycyst
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Son HJ, Kim JH, Lee HK, Park MJ, Kang DW, Ko CM
- KMID: 2277575
- Korean J Pathol.
- 2010 Aug;44(4):376-383.
BACKGROUND: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy causing anovulation in women of childbearing age. It has been well established that estrogen receptor-alpha knockout (ERalphaKO) mice display several... -
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- A priming role of local estrogen on exogenous estrogen-mediated synaptic plasticity and neuroprotection
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Chamniansawat S, Chongthammakun S
- KMID: 1383803
- Exp Mol Med.
- 2012 Jun;44(6):403-411.
The localization of estrogen (E2) has been clearly shown in hippocampus, called local hippocampal E2. It enhanced neuronal synaptic plasticity and protected neuron form cerebral ischemia, similar to those effects... -
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- Association of Estrogen Receptor 2(ESR 2) Gene Polymorphisms with Ossification of the Posterior Longitudinal Ligament of the Spine
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Kim KT, Lee SH, Kwack YH, Son ES, Park KJ, Kim DH
- KMID: 2097858
- J Korean Soc Spine Surg.
- 2012 Mar;19(1):1-7.
- doi: 10.4184/jkss.2012.19.1.1
STUDY DESIGN: Genetic screening of the estrogen receptor 2 (ESR2) genes in patients with ossification of the posterior longitudinal ligament (OPLL). OBJECTIVE: We studied the relationships between ESR2 gene polymorphisms and... -
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- The Characterization of CpG Methylation of ERalpha and ERbeta Gene in the Breast Cancer
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Kim SJ, Kim TW, Lee SY, Park SJ, Lee ES, Kang HS
- KMID: 2173523
- J Korean Breast Cancer Soc.
- 2004 Mar;7(1):8-16.
- doi: 10.4048/jkbcs.2004.7.1.8
PURPOSE: Aberrant methylation of promoter cytosine guanine dinucleotide (CpG) islands is known to be responsible for the alteration and silencing of cancer genes. The data presented here show that most... -
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