- Prescription Refill Gap of Endocrine Treatment from Electronic Medical Records as a Prognostic Factor in Breast Cancer Patients
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Lee Y, Park YR, Lee JS, Lee SB, Chung IY, Son BH, Ahn SH, Lee JW
- KMID: 2441854
- J Breast Cancer.
- 2019 Mar;22(1):86-95.
- doi: 10.4048/jbc.2019.22.e14
PURPOSE: Discontinuation of hormone therapy is known to lead to a poorer prognosis in breast cancer patients. We aimed to investigate the prescription gap as a prompt index of medication... -
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- Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-beta in colorectal cells
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He YQ, Sheng JQ, Ling XL, Fu L, Jin P, Yen L, Rao J
- KMID: 1402316
- Exp Mol Med.
- 2012 Dec;44(12):723-732.
Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors.... -
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- Marked Individual Variation in Isoflavone Metabolism After a Soy Challenge Can Modulate the Skeletal Effect of Isoflavones in Premenopausal Women
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Kwak HS, Park SY, Kim MG, Yim CH, Yoon HK, Han KO
- KMID: 1782008
- J Korean Med Sci.
- 2009 Oct;24(5):867-873.
- doi: 10.3346/jkms.2009.24.5.867
Soy-isoflavones may act as estrogenic agonists or antagonists depending on the endogenous hormone status. These clinical effects can be exerted variably in individuals by the metabolic ability to produce a... -
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- Genetic Polymorphism of CYP2D6 and Clomiphene Concentrations in Infertile Patients with Ovulatory Dysfunction Treated with Clomiphene Citrate
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Ji M, Kim KR, Lee W, Choe W, Chun S, Min WK
- KMID: 2360058
- J Korean Med Sci.
- 2016 Feb;31(2):310-314.
- doi: 10.3346/jkms.2016.31.2.310
CYP2D6 is primarily responsible for the metabolism of clomiphene citrate (CC). The purpose of the present study was to investigate the relationship between CYP2D6 genotypes, concentrations of CC and its... -
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- Estrogen Antagonist and Development of Macular Hole
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Chung SE, Kim SW, Chung HW, Kang SW
- KMID: 974326
- Korean J Ophthalmol.
- 2010 Oct;24(5):306-309.
- doi: 10.3341/kjo.2010.24.5.306
To describe the clinical and optical coherence tomography (OCT) features of a macular hole (MH) or its precursor lesion in patients treated with systemic antiestrogen agents. We reviewed the medical... -
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- Stereological Comparison of the Effects of Pentoxifylline, Captopril, Simvastatin, and Tamoxifen on Kidney and Bladder Structure After Partial Urethral Obstruction in Rats
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Shirazi M, Soltani MR, Jahanabadi Z, Abdollahifar MA, Tanideh N, Noorafshan A
- KMID: 2069919
- Korean J Urol.
- 2014 Nov;55(11):756-763.
- doi: 10.4111/kju.2014.55.11.756
PURPOSE: Limited studies have shown antifibrotic effects of pentoxifylline, captopril, simvastatin, and tamoxifen. No comparisons are available of the effects of these drugs on prevention of renal and bladder changes... -
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- Identification of a mutation in the human raloxifene response element of the transforming growth factor-3 gene
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Han KO, Kang YS, Hwang CS, Moon IG, Yim CH, Chung HY, Jang HC, Yoon HK, Han IK, Choi YK
- KMID: 2157560
- J Korean Med Sci.
- 2001 Oct;16(5):549-552.
- doi: 10.3346/jkms.2001.16.5.549
The human transforming growth factor-3 (TGF-3) is an important cytokine to maintain bone mass by inhibiting osteoclast differentiation. Recently raloxifene response element (RRE), a new enhancer with a polypurine sequence... -
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- Outcome of Immunosuppressive Therapy with Helicobacter pylori Eradication Therapy in Patients with Chronic Idiopathic Thrombocytopenic Purpura
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Song MK, Chung JS, Shin HJ, Choi YJ, Cho GJ
- KMID: 1786883
- J Korean Med Sci.
- 2008 Jun;23(3):445-451.
- doi: 10.3346/jkms.2008.23.3.445
We initiated this study to investigate whether combining Helicobacter pylori eradication with immunosuppressive therapy provides an additional benefit to patients with idiopathic thrombocytopenic purpura (ITP) that has relapsed or has... -
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- Migraine-like Headache in a Patient with Complement 1 Inhibitor Deficient Hereditary Angioedema
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Chung JY, Kim M
- KMID: 1792989
- J Korean Med Sci.
- 2012 Jan;27(1):104-106.
- doi: 10.3346/jkms.2012.27.1.104
We report on an angioedema patient with a genetic defect in complement 1 inhibitor, manifesting migraine-like episodes of headache, effective prophylaxis with Danazol, and triptan for a treatment of acute... -
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