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Two Korean Cases of Hereditary Spherocytosis Caused by Mutations in SLC4A1

Cho H, Lee JW, Chung NG, Lee SE, Jang W, Kim M, Han K, Kim Y

Hereditary spherocytosis (HS) is caused by mutations in the SPTA1, SPTB, ANK1, SLC4A1, and EPB42 genes, all of which encode erythrocyte membrane proteins. Mutations in SLC4A1, which encodes band 3...
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Erythrocyte Membrane Unsaturated (Mono and Poly) Fatty Acids Profile in Newly Diagnosed Basal Cell Carcinoma Patients

Rahrovani , Javanbakht MH, Ghaedi E, Mohammadi , Ehsani AH, Esrafili A, Djalali M

Studies have reported different changes in the fatty acid composition of red blood cell (RBC) total lipids in patients with various types of cancer. It has been indicated that n-3/n-6...
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Effects of Erythrocyte Membrane Polyunsaturated Fatty Acids in Overweight, Obese, and Morbidly Obese Korean Women

Choi HN, Yim JE

BACKGROUND: The levels of erythrocyte polyunsaturated fatty acids (FAs) may be associated with obesity, metabolic syndrome, and cancer. Thus, we investigated the association between erythrocyte n−3 and n−6 FA composition,...
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Lecithin: Cholesterol Acyltransferase and Na(+)-K(+)-ATPase Activity in Patients with Breast Cancer

Ozmen HK, Askin S

PURPOSE: The aim of this study was to determine whether plasma lecithin:cholesterol acyltransferase (pLCAT) and erythrocyte membrane Na(+)-K(+)-ATPase ase (emNaKATPs) activity have a correlation in breast cancer. This study compared...
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Hereditary Spherocytosis

Park ES

  • KMID: 2049272
  • Clin Pediatr Hematol Oncol.
  • 2012 Oct;19(2):57-63.
Hereditary spherocytosis is a hemolytic anemia caused by erythrocyte membrane deficiencies that lead to membrane destabilization and vesiculation. Abnormal spherocytes are trapped and destroyed in the spleen. Mutations in several...
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Effects of green tea or Sasa quelpaertensis bamboo leaves on plasma and liver lipids, erythrocyte Na efflux, and platelet aggregation in ovariectomized rats

Ryou SH, Kang MS, Kim KI, Kang YH, Kang JS

  • KMID: 2313581
  • Nutr Res Pract.
  • 2012 Apr;6(2):106-112.
This study was conducted to investigate the effects of Sasa quelpaertensis bamboo and green tea on plasma and liver lipids, platelet aggregation, and erythrocyte membrane Na channels in ovariectomized (OVX)...
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Associations between Lead Exposure and Dose and Protein Kinase C Activation in Erythrocytes Among Lead Workers

Hwang KY, Hwangbo Y, Ahn HC, Kim YB, Lee GS, Lee SS, Ahn KD, Lee BK

  • KMID: 2028161
  • Korean J Occup Environ Med.
  • 2001 Dec;13(4):369-375.
OBJECTIVES: Protein kinase C(PKC), a calcium and phospholipid dependent enzyme, is activated by lead in vitro at picomolar concentrations. However, the effect of lead on PKC has never been studied...
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Abnormalities of erythrocyte membrane proteins in Korean patients with hereditary spherocytosis

Lee YK, Cho HI, Park SS, Lee YJ, Ra E, Chang YH, Hur M, Shin HY, Ahn HS

Hereditary spherocytosis (HS) is a common inherited erythrocyte membrane disorder characterized by chronic hemolytic anemia. Clinical manifestations and biochemical abnormalities of HS are heterogeneous. In this study, we investigated erythrocyte...
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SDS-PAGE Analysis of Red Cell Membrane Proteins in Hereditary Hemolytic Anemia

Lee YK, Cho HI, Park SS, Ra E, Chang YH, Hur M, Lee YJ, Shin HY, Ahn HS

  • KMID: 1533972
  • Korean J Hematol.
  • 1999 Nov;34(4):559-567.
BACKGROUND: Red cell membrane is a lipid bilayer laminated by the membrane cytoskeleton at the surface of inner monolayer. A class of hemolytic anemia, such as hereditary spherocytosis (HS) or...
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Effect of Cu Zn Levels on Superoxide Dismutase Activity in Erythrocytes from Patients with end Stage Renal Disease

Mun KC, Kwon JK

  • KMID: 1990079
  • Korean J Nephrol.
  • 1999 Mar;18(2):265-269.
Suppressed superoxide dismutase activity, which is responsible for the dismutation of superoxide anion to hydrogen peroxide, is known to be one of the factors leading to lipid peroxidation in the erythrocyte membrane...
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Antioxidative Effect of Melatonin in Streptozotocin-Induced Diabetic Rats

Yoo HJ, Moon DH, Chung HB, Ahn MS, Yoon KS, Ahn BJ, Shin J, Chung AC, Cho YJ, Nahm HW

  • KMID: 1853225
  • J Korean Soc Endocrinol.
  • 1998 Mar;13(1):45-51.
BACKGROUND: An increase in oxidative stress has been suggested to play major roles in the complications of diabetes. The bulk of the experimental data favors enhanced free radicals in diabetes...
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Erythrocyte Membrane Protein Alterations by SDS-PAGE and Underlying Clinical Heterogeneity in Hereditary Spherocytosis

Yoo ES, Choi HS, Shin HY, Ahn HS, Lee YK, Cho HI

  • KMID: 1979968
  • Korean J Pediatr Hematol Oncol.
  • 1997 Oct;4(2):261-272.
BACKGROUND: Hereditary spherocytosis(HS) is a clinically and biochemically very heterogeneous disorder The purpose of this study is to detect erythrocyte membrane protein abnormalities by SDS-PAGE and to investigate the frequency...
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The Effect of Hydroxyl Radical Generation on the Cytotoxicity of Alveolar Macrophage and Lipid Peroxidation of Erythrocyte Membrane by Mineral Fibers

Kim KA, Lim Y, Kim JH, Chang HS, Park CY, Yun IG, Oh MH

  • KMID: 1529780
  • Korean J Occup Environ Med.
  • 1997 Oct;9(3):401-410.
No abstract available.
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Erythrocyte Band 7 Integral Protein Defect in Congenital Hemolytic Anemia: Hereditary Stomatocytosis

Sim CS, Han SJ, Lee HJ, Park WI, Lee KJ, Chung SY, Wee S, Choi EY

  • KMID: 2335230
  • J Korean Pediatr Soc.
  • 1997 Feb;40(2):260-265.
Hereditary stomatocytosis is a rare congenital hemolytic anemia, named after mouth shaped or stomatocytic erythrocyte morphology. In this report, we present a case of a hereditary stomatocytosis in a 1...
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Splenectomy in Hereditary Spherocytosis in Childhood

Heo YS, Kim CS, Do BS, Suh BY, Hah JO

Among the erythrocyte membrane defects, hereditary spherocytosis is the most common. The erythrocyte membrane defect results from a deficiency of spectrin, the most important structural protein in red cell. Hereditary spherocytosis...
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Effects of Dantrolene on the Interaction of Calcium and Erythrocyte Membrane

Kang BS

Dantrolene sodium in vitro inhibited the ATP-dependent efflux of calcium from human Fed cells, the Ca++-ATPase activity of red blood cell membrane fragments (RBCMF) and passive calcium binding to RBCMF....
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Purification of Band 3 from the Human Erythrocyte Membrane and its Incorporation into Liposome

Kim JR, Kim JH, Lee KY

Band 3, the predominant 95,000 dalton anion transport protein, is the major intrinsic glycoprotein of the human erythrocyte membrane. This anion carrier exists as a dimer and binds the cytoskeletons...
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The Effects of Physical States of Phospholipids on the Incorporation and CB Binding Activity of Band 4.5 Protein of human Erythrocyte Membrane in Reconstituted Vesicles

Hah JS

Proteoliposomes were prepared by reconstitution of a solubilized band 4.5 protein of human erythrocyte membrane with a mixture of phosphatidylcholine(PC) and phosphatidylethanolamine(PE) of varying ratios. The incorporation of the band...
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Effects of Dopamine and Ephedrine on Na-K-ATPase Activity in the Red Cell Ghosts of Rabbits

Park ST, Choi SJ, Kim KJ

  • KMID: 2240876
  • Korean J Anesthesiol.
  • 1985 Mar;18(1):35-45.
Na-K-ATPase, which is activated by Na+ and K+ at physiologic concentrations, is most abundantly present in tissues which have a high capacity for sodium and potassium transport, and the activity...
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Developmental Changes of Membrane Proteins from Human Erythrocytes

Joo CU, Lee HS, Kim JS, Kim KC, Kim HR

  • KMID: 1699464
  • J Korean Pediatr Soc.
  • 1982 Jun;25(6):541-546.
To investigate the developmental changes of human erythrocytes, adult and fetal erythrocyte membranes prepared from adult and cord blood were analyzed in regard to their proteins, glycoproteins, enzyme activities and...
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