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Identification of Soluble Epoxide Hydrolase Inhibitors from the Seeds of Passiflora edulis Cultivated in Vietnam

Cuong TD, Thi Ngoc Anh H, Huong TT, Khanh PN, Ha VT, Hung TM, Kim YH, Cuong NM

Soluble epoxide hydrolases (sEH) are enzymes present in all living organisms, metabolize epoxy fatty acids to 1,2-diols. sEH in the metabolism of polyunsaturated fatty acids plays a key role in...
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Genetic Polymorphism of Epoxide Hydrolase and GSTM1 in Chronic Obstructive Pulmonary Disease

Park SS, Kim EJ, Son CY, Wi JO, Park KH, Cho GJ, Ju JY, Kim KS, Kim YI, Lim SC, Kim YC, Park KO, Na KJ

BACKGROUND: Although smoking is a major cause of chronic obstructive pulmonary disease (COPD), only 10-20% of cigarette smokers develop symptomatic COPD, which suggests the presence of genetic susceptibility. This genetic...
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Interactions Between Bisphenol A Exposure and GSTP1 Polymorphisms in Childhood Asthma

Lin TJ, Karmaus WJ, Chen ML, Hsu JC, Wang IJ

PURPOSE: Bisphenol A (BPA) exposure may increase the risk of asthma. Genetic polymorphisms of oxidative stress-related genes, glutathione S-transferases (GSTM1, GSTP1), manganese superoxide dismutase, catalase, myeloperoxidase, and microsomal epoxide hydrolase...
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