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Regulation of Type IV Collagen alpha Chains of Glomerular Epithelial Cells in Diabetic Conditions

Ha TS, Hong EJ, Ahn EM, Ahn HY

An early feature of diabetic nephropathy is the alteration of the glomerular basement membrane (GBM), which may result in microalbuminuria, subsequent macroproteinuria, and eventual chronic renal failure. Although type IV...
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Efficient Cultivation Conditions for Human Limbal Epithelial Cells

Kim MK, Lee JL, Oh JY, Shin MS, Shin KS, Wee WR, Lee JH, Park KS, Son YS

To compare the stem niche in different culture conditions of limbal epithelial cells, the suspended human limbal epithelial cells (HLECs) were seeded on the 3T3-pretreated plates and the other suspended...
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Activation of NF-κB and AP-1 Mediates Hyperproliferation by Inducing β-Catenin and c-Myc in Helicobacter pylori-Infected Gastric Epithelial Cells

Byun E, Park B, Lim JW, Kim H

PURPOSE: In the gastric mucosa of Helicobacter pylori (H. pylori)-infected patients with gastritis or adenocarcinoma, proliferation of gastric epithelial cells is increased. Hyperproliferation is related to induction of oncogenes, such...
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Nucleotide Binding Oligomerization Domain 1 Is an Essential Signal Transducer in Human Epithelial Cells Infected with Helicobacter pylori That Induces the Transepithelial Migration of Neutrophils

Kim BJ, Kim JY, Hwang ES, Kim JG

BACKGROUND/AIMS: The cytosolic host protein nucleotide binding oligomerization domain 1 (Nod1) has emerged as a key pathogen recognition molecule for innate immune responses in epithelial cells. The purpose of the...
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MUC Expression in Gallbladder Epithelial Tissues in Cholesterol-Associated Gallbladder Disease

Yoo KS, Choi HS, Jun DW, Lee HL, Lee OY, Yoon BC, Lee KG, Paik SS, Kim YS, Lee J

BACKGROUND/AIMS: Gallstone pathogenesis is linked to mucin hypersecretion and bacterial infection. Several mucin genes have been identified in gallbladder epithelial cells (GBECs). We investigated MUC expression in cholesterol-associated gallbladder disease...
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Identification of potential lung cancer biomarkers using an in vitro carcinogenesis model

Kim JE, Koo KH, Kim YH, Sohn J, Park YG

Lung cancer is one of the deadliest and commonly diagnosed neoplasms. Early diagnosis of this disease is critical for improving clinical outcome and prognosis. Because the early stages of lung...
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Role of TGFBIp in Wound Healing and Mucin Expression in Corneal Epithelial Cells

Maeng YS, Lee GH, Lee B, Choi SI, Kim TI, Kim EK

PURPOSE: Transforming growth factor-β-induced protein (TGFBIp) is highly expressed in the cornea, and mutant TGFBIp induces corneal diseases. However, the function of TGFBIp in cornea epithelium is not fully investigated....
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