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Endothelial Dysfunction: Clinical Implications in Cardiovascular Disease and Therapeutic Approaches

Park KH, Park WJ

Atherosclerosis is a chronic progressive vascular disease. It starts early in life, has a long asymptomatic phase, and a progression accelerated by various cardiovascular risk factors. The endothelium is an...
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Expression of LFA-3(CD58) After Intracorneal Infection of Candida albicans in Rabbits

Jeong JW, Sohn SW, Hur B, Hahn YH

  • KMID: 2123782
  • J Korean Ophthalmol Soc.
  • 1998 Dec;39(12):2875-2884.
In this immunohistochemical study we applied a monoclonal antibody(mAb) to evaluate the expression pattern of lymphocyte functionassociated antigen 3(LFA-3) in rabbit`s corneas before and after intracorneal injection of Candida albicans....
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The Role of AMPK in Vascular Endothelium

Lee WJ, Kim JY, Koh EH, Han SM, Kim MS, Lee KU, Park JY

  • KMID: 2177798
  • J Korean Diabetes Assoc.
  • 2005 Jan;29(1):1-5.
No abstract available.
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Role of Endothelium -Derived Relaxing Factor in the Pathogenesis of Coronary Artery Spasm and Its Relationship with Ethanol

Seo JD, Song JK, Kim CH, Sohn DW, Oh BH, Lee MM, Park YB, Choi YS, Lee YW

Isometric tension recording was performed in the transverse strips of porcine coronary arteries and rabbit aorta to observe the effects of the endothelium and endothelium-derived relaxing factor(EDRF) on vasomotor tone...
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The Immunohistochemical Localization of CD44 in Rabbit and Human Cornea

Lee JS, Hwang SH, Jeong G, Yun S

  • KMID: 1950317
  • J Korean Ophthalmol Soc.
  • 1995 Aug;36(8):1331-1337.
The CD44 protein has a functional domain for binding hyaluronic acid, maintaining the integrity and structure of the epithelium. The purpose of this study is to evaluate the presence and...
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Acute Vascular Rejection 11 Months after Heart Transplantation

Kim HW, Seo JW, Kim WH, Kim YI, Lee HS

  • KMID: 2324290
  • J Korean Soc Transplant.
  • 2001 Jun;15(1):114-118.
Vascular rejection injures the vascular endothelium in cardiac allografts in the absence of significant intramyocardial lymphocytic infiltration. When compared with cellular rejection, acute vascular rejection occurs earlier after transplantation, and...
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Lysophosphatidylcholine Attenuates Endothelium-dependent Relaxation Responses through Inhibition of ACh-induced Endothelial [Ca2+]i Increase

Kwon SC, Lee YH, Nam T, Ahn DS

  • KMID: 1512938
  • Korean J Physiol Pharmacol.
  • 2006 Feb;10(1):25-30.
Lysophosphatidylcholine (LPC), which accumulates in atherosclerotic arteries, has been reported to inhibit endothelium-dependent relaxation (EDR) in many different species. However, the underlying mechanism of LPC-induced inhibition of EDR is still...
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Detrimental Effects of Endovascular Intervention in Active Rheumatoid Vasculitis

Park JK

Balloon angioplasty can cause shear stress and tear of the vascular endothelium during mechanical dilatation, leading to increased inflammation and coagulation reactions of the vascular endothelium. Herein, a worst case...
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Impairing effects of acute glucose overload on calcium homeostasis in vascular endothelial cells

Oike M, Kimura C

  • KMID: 2071823
  • Korean J Physiol Pharmacol.
  • 1998 Dec;2(6):653-659.
SUMMARY AND PERSPECTIVE We demonstrated two kinds of impairing effect of glucose overload on endothelial Ca2+ mobilization; i.e., 02- mediated and protein kinase C-mediated ones. As already mentioned in the...
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A Case of Parital Sinus Pericranii

Park HS, Jung S, Lee JH

  • KMID: 1672258
  • J Korean Neurosurg Soc.
  • 1995 Nov;24(11):1438-1443.
Sinus pericranii is a rare vascular anomaly which is defined as a group of abnormal communications between the extracranial and intracranial venous systems, usually involving the superior sagittal sinus. A...
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Altered Transendothelial Transport of Hormones as a Contributor to Diabetes

Yoon N, Dang TQ, Chasiotis , Kelly SP, Sweeney G

The vascular endothelium is a dynamic structure responsible for the separation and regulated movement of biological material between circulation and interstitial fluid. Hormones and nutrients can move across the endothelium...
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Expression of Vascular Cell Adhesion Molecule-1 on Vascular Endothelium in Nasal Polyps with Topical Steroid Treatment

Min YG, Jung YH, Kim JW, Rhee CS, Lee SS, Won TB, Oh SJ

  • KMID: 2275824
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Nov;44(11):1164-1167.
BACKGROUND AND OBJECTIVES: Topical steroid therapy may play an important role in reducing the vascular cell adhesion molecule-1(VCAM-1) expression in the nasal polyp. Various adhesion molecules such as VCAM-1 promote...
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Expression of Intercellular Adhesion Molecule-l (ICAM-1) in Vascular Endothelium and Keratinocytes of Psoriatic Skin

Ban DH, Koo SW, Kim YK, Choi GS, Lee JH

BACKGROUND: The endothelial expresson and upregulation of ICAM-1 and epidermal keratinocyte expression of ICAM-1 are well documented in psoriasis. ICAM-1 mediates the adhesion and trafficking of circulating activated skin-seeking CD45RO+...
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Cyclosporine-induced Vascular Endothelial Dysfunction in Rats

Hoh SY, Lee JU

  • KMID: 2307301
  • Korean J Nephrol.
  • 1999 Sep;18(5):683-691.
Cyclosporine(CsA) has been known to cause an endothelial dysfunction following its use as an immunosuppressive agent. On the other hand, the vascular endothelium has been recognized as an endocrine organ...
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A comparison of the relaxation responses of isolated cavernosal smooth muscles by endothelium-independent and endothelium-dependent vasodilators in diabetic men with impotenc

Kim SC, Ahn SY, Park SH, Lee MY, Uhm DY

This study was intended to explore the effects of endothelium-independent, direct smooth muscle relaxants(papaverine, verapamil) and endothelium-dependent vasodilators(acetylcholine, bradykinin, adenosine) on the isolated cavernosal smooth muscle strips taken from diabetic...
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Effects of Na+, K(+)-pump inhibitors on acetylcholine-induced relaxation in the rabbit aorta

Lee YH, Ahn DS, Song HJ, Kim YH, Kim HS, Ahn SH, Kang BS

The purpose of this study was to investigate the effects of inhibitors of the Na+, K(+)-pump and membrane depolarizing agents on endothelium-dependent acetylcholine-induced relaxation in the rabbit thoracic aorta. Aortic...
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Insulin Resistance and Erectile Dysfunction

Kim SC

Insulin resistance is a hallmark of metabolic syndrome, including type 2 diabetes mellitus and obesity which are characterized by endothelial dysfunction. The endothelial dysfunction leads to erectile dysfunction (ED). Thus,...
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A Case of Thoracic Angiosarcoma

Lee SH, Chung YK, Lee HK, Chu JH, Lee KC, Lee YS

  • KMID: 2068037
  • J Korean Neurosurg Soc.
  • 1994 Dec;23(12):1443-1448.
Angiosarcoma of spine is a rare neoplasm derived from vascular endothelium. Synonymous term include hemangiosarcoma and malignant hemangioendothelioma. The authors present the clinical, radiological and pathological features of a patient...
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Vascular Endothelial Dysfunction and Exercise in Metabolic Syndrome Patients

Hwang MH, Sim YJ

Metabolic syndrome, a constellation of cardiovascular disease risk factors, is a global pandemic. Over 30% of the adult population in both South Korea and the United States are currently classified...
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Distribution of Adhesion Molecules in Rabiit Cornea with Aspergillus fumigatus Keratitis

Choi SY, Seo DS, Hur B, Hahn YH

  • KMID: 2336771
  • J Korean Ophthalmol Soc.
  • 1999 Feb;40(2):318-329.
In order to help define the possible role of adhesion molecules in corneal inflammation, we investigated the distribution of adhesion molecules in normal and Aspergillus fumigatus keratitis-induced corneas of rabbits...
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