- Hypoxia induces Wee1 expression and attenuates hydrogen peroxide-induced endothelial damage in MS1 cells
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Hong KS, Kim HS, Kim SH, Lim DJ, Park JY, Kim SD
- KMID: 1058702
- Exp Mol Med.
- 2011 Dec;43(12):653-659.
- doi: 10.3858/emm.2011.43.12.074
In an oxygen-depleted environment, endothelial cells initiate an adaptive pattern of synthesis, which may enable them to survive hypoxic crises. Using high-resolution two-dimensional gel electrophoresis in conjunction with mass spectroscopy,... -
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- Evaluation of Stem Cell Components in Retrocorneal Membranes
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Lee SH, Kim KW, Kim MK, Chun YS, Kim JC
- KMID: 1796949
- J Korean Med Sci.
- 2014 Jun;29(6):846-851.
- doi: 10.3346/jkms.2014.29.6.846
The purpose of this study was to elucidate the origin and cellular composition of retrocorneal membranes (RCMs) associated with chemical burns using immunohistochemical staining for primitive cell markers. Six cases... -
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- Morphine Postconditioning Attenuates ICAM-1 Expression on Endothelial Cells
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Min TJ, Kim JI, Kim JH, Noh KH, Kim TW, Kim WY, Lee YS, Park YC
- KMID: 1782121
- J Korean Med Sci.
- 2011 Feb;26(2):290-296.
- doi: 10.3346/jkms.2011.26.2.290
The purpose of this study is to determine 1) whether morphine postconditiong (MPostC) can attenuate the intercellular adhesion molecules-1 (ICAM-1) expression after reoxygenation injury and 2) the subtype(s) of the... -
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- Galpha12 Protects Vascular Endothelial Cells from Serum Withdrawal-Induced Apoptosis through Regulation of miR-155
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Lee HJ, Lee EJ, Seo M
- KMID: 2466377
- Yonsei Med J.
- 2016 Jan;57(1):247-253.
- doi: 10.3349/ymj.2016.57.1.247
PURPOSE: Apoptosis of vascular endothelial cells is a type of endothelial damage that is associated with the pathogenesis of cardiovascular diseases such as atherosclerosis. Heterotrimeric GTP-binding proteins (G proteins), including... -
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- Inhibition of corneal neovascularization by rapamycin
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Kwon YS, Kim JC
- KMID: 1111410
- Exp Mol Med.
- 2006 Apr;38(2):173-179.
The purpose of this study was to determine whether rapamycin could inhibit corneal angiogenesis induced by basic fibroblast growth factor (bFGF). Using human dermal microvascular endothelial cells (HDMECs), we examined... -
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- Mechanism of Humoral and Cellular Immune Modulation Provided by Porcine Sertoli Cells
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Lee HM, Oh BC, Lim DP, Lee DS, Lim HG, Park CS, Lee JR
- KMID: 1786893
- J Korean Med Sci.
- 2008 Jun;23(3):514-520.
- doi: 10.3346/jkms.2008.23.3.514
The understanding of main mechanisms that determine the ability of immune privilege related to Sertoli cells (SCs) will provide clues for promoting a local tolerogenic environment. In this study, we... -
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- Regulation of Glomerular Endothelial Cell Proteoglycans by Glucose
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Ha TS, Duraisamy , Faulkner J, Kasinath B
- KMID: 1733484
- J Korean Med Sci.
- 2004 Apr;19(2):245-252.
- doi: 10.3346/jkms.2004.19.2.245
The presence of heparan sulfate proteoglycan (HSPG) in anionic sites in the lamina rara interna of glomerular basement membrane suggests that the proteoglycan may be deposited by the glomerular endothelial... -
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- Monocrotaline-induced pulmonary hypertension correlates with upregulation of connective tissue growth factor expression in the lung
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Lee YS, Byun J, Kim JA, Lee JS, Kim KL, Suh YL, Kim JM, Jang HS, Lee JY, Shin IS, Suh W, Jeon ES, Kim DK
- KMID: 1033098
- Exp Mol Med.
- 2005 Feb;37(1):27-35.
Pulmonary hypertension (PH) is characterized by structural and functional changes in the lung including proliferation of vascular smooth muscle cells (VSMCs) and excessive collagen synthesis. Although connective tissue growth factor... -
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- Tissue Responses to Endovascular Stent Grafts for Saccular Abdominal Aortic Aneurysms in a Canine Model
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Kim HB, Choi YH, So YH, Min SK, Kim HC, Kim YI, Park JH, Chung JW
- KMID: 1778822
- J Korean Med Sci.
- 2012 Oct;27(10):1170-1176.
- doi: 10.3346/jkms.2012.27.10.1170
We investigated tissue responses to endoskeleton stent grafts for saccular abdominal aortic aneurysms (AAAs) in canines. Saccular AAAs were made with Dacron patch in 8 dogs, and were excluded by... -
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- A serum-stable branched dimeric anti-VEGF peptide blocks tumor growth via anti-angiogenic activity
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Kim JW, Kim TD, Hong BS, Kim OY, Yoon WH, Chae CB, Gho YS
- KMID: 1104211
- Exp Mol Med.
- 2010 Jul;42(7):514-523.
- doi: 10.3858/emm.2010.42.7.052
Angiogenesis is critical and indispensable for tumor progression. Since VEGF is known to play a central role in angiogenesis, the disruption of VEGF-VEGF receptor system is a promising target for... -
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- Tissue engineering of heart valves by recellularization of glutaraldehyde-fixed porcine valves using bone marrow-derived cells
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Kim SS, Lim SH, Cho SW, Gwak SJ, Hong YS, Chang BC, Park MH, Song KW, Choi CY, Kim BS
- KMID: 1094153
- Exp Mol Med.
- 2006 Jun;38(3):273-283.
To increase the biocompatibility and durability of glutaraldehyde (GA)-fixed valves, a biological coating with viable endothelial cells (ECs) has been proposed. However, stable EC layers have not been formed successfully... -
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- Cathepsin L derived from skeletal muscle cells transfected with bFGF promotes endothelial cell migration
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Chung JH, Im EK, Jin T, Lee SM, Kim SH, Choi EY, Shin MJ, Lee KH, Jang Y
- KMID: 1104387
- Exp Mol Med.
- 2011 Apr;43(4):179-188.
- doi: 10.3858/emm.2011.43.4.022
Gene transfer of basic fibroblast growth factor (bFGF) has been shown to induce significant endothelial migration and angiogenesis in ischemic disease models. Here, we investigate what factors are secreted from... -
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