- Neurophyisological and Neurocognitive Endophenotypes for Schizophrenia Genetics Research
-
Joo YH
- KMID: 2315798
- Psychiatry Investig.
- 2008 Dec;5(4):199-202.
There is growing interest in the genetic analysis of schizophrenia using endophenotypes rather than clinical diagnosis or symptom dimensions. Endophenotypes could be alternative phenotypes for the clinical phenotypes. With their... -
- CITED
-
- Close
- SHARE
-
- Close
- P50 and Schizophrenia
-
Lee SH, Seo HS, Chung YC
- KMID: 1511821
- Korean J Biol Psychiatry.
- 2006 Aug;13(3):137-143.
One of the most widely recognized neurophysiologic endophenotypes for schizophrenia is deficient gating or inhibition of the P50 component of the auditory event-related potential(ERP). A deficit in P50 sensory gating... -
- CITED
-
- Close
- SHARE
-
- Close
- Neuroimaging Findings in Subjects at High Risk for Developing Schizophrenia
-
Choi JS, Kwon JS
- KMID: 2341481
- J Korean Neuropsychiatr Assoc.
- 2008 Sep;47(5):430-440.
The pathophysiology of schizophrenia may be influenced by interaction of genetic, neurodevelopmental, environmental and/or psychological factors, which make it difficult to elucidate the etiology of the disorders through clinical phenomenology.... -
- CITED
-
- Close
- SHARE
-
- Close
- Shared and Distinct Neurocognitive Endophenotypes of Schizophrenia and Psychotic Bipolar Disorder
-
Kim D, Kim J, Koo T, Yun H, Won S
- KMID: 2171069
- Clin Psychopharmacol Neurosci.
- 2015 Apr;13(1):94-102.
- doi: 10.9758/cpn.2015.13.1.94
OBJECTIVE: Schizophrenia and bipolar disorder are characterized by the presence of neurocognitive impairments on the psychosis continuum. The present study aimed to explore the shared and distinct endophenotypes between these... -
- CITED
-
- Close
- SHARE
-
- Close
- At Risk State for Psychosis: Related Issues and Future Directions
-
Roh D, Kim CH
- KMID: 2299893
- Korean J Biol Psychiatry.
- 2011 Nov;18(4):203-209.
In medicine, general clinical practice moves in the direction of early detection and intervention for the prevention of progressive disease. In psychiatry, research in subjects with the risk syndrome for... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparison of Cognitive Control Deficits in Patients with Schizophrenia and Their Unaffected First-Degree Relatives
-
Yun H, Woo S, Lee SW, Won S
- KMID: 2379387
- J Korean Neuropsychiatr Assoc.
- 2017 May;56(2):61-67.
- doi: 10.4306/jknpa.2017.56.2.61
OBJECTIVES: This study aimed to identify the differences in the profiles of cognitive control deficits among schizophrenic patients and endophenotypes. METHODS: The study examined three groups: remitted patients with schizophrenia (n=54),... -
- CITED
-
- Close
- SHARE
-
- Close
- The Study About Intra-Familial Transmission of the Neurological Soft Signs in Schizophrenia
-
Yoo S, Choi Y, Lee S, Shin C, Kim S, Son J
- KMID: 1481599
- Korean J Biol Psychiatry.
- 2008 May;15(2):83-90.
OBJECTIVES: Neurological soft signs have been regarded as endophenotypes associated with the genetic basis of schizophrenia. This study was to investigate the intra-familial correlations of the neurological soft signs according... -
- CITED
-
- Close
- SHARE
-
- Close
- Neuropsychological and Behavioral Profiles in Attention-Deficit Hyperactivity Disorder Children of Parents with a History of Mood Disorders: A Pilot Study
-
Park S, Hong KE, Yang YH, Kang J, Park EJ, Ha K, Park M, Yoo HJ
- KMID: 2316333
- Psychiatry Investig.
- 2014 Jan;11(1):65-75.
OBJECTIVE: We aimed to investigate the neurocognitive and behavioral endophenotypes of premorbid mood disorder. We compared intelligence, neuropsychological functioning, and behavioral problems among three groups: 1) a high-risk group [attention-deficit... -
- CITED
-
- Close
- SHARE
-
- Close
- Genetic Studies of Psychiatric Disorders: The Basic Concepts and Methods of Quantitative Genetics
-
Joo EJ, Kim YS
- KMID: 2340432
- J Korean Neuropsychiatr Assoc.
- 2000 Mar;39(2):257-272.
Quantitative medical genetics including genetic epidemiological studies, linkage studies, and association studies are the basis for molecular genetic studies to find the susceptible genes or responsible mutations for psychiatric disorders.... -
- CITED
-
- Close
- SHARE
-
- Close
- Comparing Intelligence Test Profiles to Assess Tourette's Disorder with Attention-Deficit Hyperactivity Disorder
-
Kim WH, Park TW, Park J, Chung SK, Yang JC, Park JI, Kim EJ, Cho EC, Park JC
- KMID: 2369529
- J Korean Acad Child Adolesc Psychiatry.
- 2017 Jan;28(1):25-30.
- doi: 10.5765/jkacap.2017.28.1.25
OBJECTIVES: The study compared the intelligence test profiles of Tourette's Disorder (TD), attention-deficit hyperactivity disorder (ADHD), and TD with ADHD (TD+ADHD) groups. METHODS: The Korean Wechsler Intelligence Scale for Children-third edition... -
- CITED
-
- Close
- SHARE
-
- Close
- Genome-Wide Association Scan of Korean Autism Spectrum Disorders with Language Delay: A Preliminary Study
-
Cho SC, Yoo HJ, Park M, Cho IH, Kim BN, Kim JW, Shin MS, Park TW, Son JW, Chung US, Kim HW, Yang YH, Kang JO, Yang SY, Kim SA
- KMID: 2315930
- Psychiatry Investig.
- 2011 Mar;8(1):61-66.
OBJECTIVE: Communication problems are a prevalent symptom of autism spectrum disorders (ASDs), which have a genetic background. Although several genome-wide studies on ASD have suggested a number of candidate genes,... -
- CITED
-
- Close
- SHARE
-
- Close
- No Association between (AAT)n Repeat Polymorphisms in the Cannabinoid Receptor 1 Gene and Smooth Pursuit Eye Movement Abnormality in Korean Patients with Schizophrenia
-
Kim MJ, Kim CR, Park JW, Pak DH, Shin HD, Choi IG, Hahn SW, Hwang J, Lee YJ, Woo SI
- KMID: 2361590
- Korean J Biol Psychiatry.
- 2016 Nov;23(4):148-156.
- doi: 10.0000/kjbp.2016.23.4.148
OBJECTIVES: According to previous studies, the cannabinoid receptor 1 (CNR1) gene could be an important candidate gene for schizophrenia. Some studies have linked the (AAT)n trinucleotide repeat polymorphism in CNR1... -
- CITED
-
- Close
- SHARE
-
- Close
- Riluzole Selective Antioxidant Effects in Cell Models Expressing Amyotrophic Lateral Sclerosis Endophenotypes
-
Sala G, Arosio A, Conti E, Beretta S, Lunetta C, Riva N, Ferrarese , Tremolizzo L
- KMID: 2457408
- Clin Psychopharmacol Neurosci.
- 2019 Aug;17(3):438-442.
- doi: 10.9758/cpn.2019.17.3.438
OBJECTIVE: Until recently, riluzole was the only drug licensed for amyotrophic lateral sclerosis (ALS). In spite of its efficacy, the mechanism of action remains elusive, and both blocking of glutamate... -
- CITED
-
- Close
- SHARE
-
- Close
- Prepulse Inhibition of Startle Response: Recent Advances in Human Studies of Psychiatric Disease
-
Takahashi , Hashimoto , Iwase M, Ishii R, Kamio Y, Takeda M
- KMID: 2171253
- Clin Psychopharmacol Neurosci.
- 2011 Dec;9(3):102-110.
Prepulse inhibition (PPI) is considered to be one of the most promising neurophysiological indexes for translational research in psychiatry. Impairment of PPI has been reported in several psychiatric diseases, particularly... -
- CITED
-
- Close
- SHARE
-
- Close
- Genetic and Neurobiological Etiologies of Alcohol Dependence
-
Kim SG, Moon ES
- KMID: 2341037
- J Korean Neuropsychiatr Assoc.
- 2004 Nov;43(6):626-632.
The etiologies of alcohol dependence may be divided into three factors:biological, psychological, and social factors. Among these, many of the current articles deal with the genetic factors, due to rapid... -
- CITED
-
- Close
- SHARE
-
- Close
- The Contingent Negative Variation in Remitted Paediatric Bipolar Patients: No Evidence of Abnormality
-
Banerjee N, Sinha VK, Jayaswal M, Desarkar P
- KMID: 2316268
- Psychiatry Investig.
- 2013 Jun;10(2):196-199.
Although the Contingent Negative Variation (CNV) paradigm has been useful in schizophrenia, limited research involving such paradigm in subjects with Bipolar Disorder (BD) has produced contradictory findings. To the best... -
- CITED
-
- Close
- SHARE
-
- Close
- A Study of Neurological Soft Signs in Patients with Schizophrenia and Their Unaffected Siblings
-
Cho JW, Kim SH, Lee YS
- KMID: 2361594
- Korean J Biol Psychiatry.
- 2016 Nov;23(4):179-184.
- doi: 10.0000/kjbp.2016.23.4.179
OBJECTIVES: This study was conducted to investigate the possibility of neurological soft signs as an endophenotype for schizophrenia by examining neurological soft signs in patients, their unaffected siblings and normal... -
- CITED
-
- Close
- SHARE
-
- Close
- Brain Theranostics and Radiotheranostics: Exosomes and Graphenes In Vivo as Novel Brain Theranostics
-
Suh M, Lee DS
- KMID: 2431978
- Nucl Med Mol Imaging.
- 2018 Dec;52(6):407-419.
- doi: 10.1007/s13139-018-0550-9
Brain disease is one of the greatest threats to public health. Brain theranostics is recently taking shape, indicating the treatments of stroke, inflammatory brain disorders, psychiatric diseases, neurodevelopmental disease, and... -
- CITED
-
- Close
- SHARE
-
- Close
- Understanding of Neural Mechanism of Mood Disorders: Focused on Neuroimaging Findings
-
Kim YR, Lee KU
- KMID: 1502559
- Korean J Biol Psychiatry.
- 2011 Feb;18(1):15-24.
Mood disorder is unlikely to be a disease of a single brain region or a neurotransmitter system. Rather, it is now generally viewed as a multidimensional disorder that affects many... -
- CITED
-
- Close
- SHARE
-
- Close
- Theory of Mind Deficits in Schizophrenia Patients and Their First-Degree Relatives
-
Lee JI, Lee SH, Kim SY, Bae SM
- KMID: 2341528
- J Korean Neuropsychiatr Assoc.
- 2009 Mar;48(2):86-91.
OBJECTIVES : Theory of mind (ToM) is the ability to conceptualize other people's mental states in order to explain their behavior. This study compared the ToM ability of schizophrenia patients,... -
- CITED
-
- Close
- SHARE
-
- Close
